Motesanib

Product Name: Motesanib
CAS No.: 453562-69-1
Chemical Name: Motesanib
Synonyms: D06678;CS-1108;motesanib;Motesanib Base;AMG 706; AMG-706;AMG-706(Motesanib);Motesanib (AMG-706) Base);2,4-Imidazolidinedione,5-(3-bromophenyl)-6-methyl-;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
CBNumber: CB01518524
Molecular Formula: C22H23N5O
Formula Weight: 373.45
MOL File: 453562-69-1.mol

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Motesanib Property

Melting point:: 147-150°C
Boiling point:: 517.3±50.0 °C(Predicted)
Density: 1.251
storage temp.: Refrigerator
solubility: DMSO (Slightly), Methanol (Slightly)
form: White powder solid.
pka: 11.75±0.40(Predicted)
color: Pale Yellow

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M732500
Product name: Motesanib
Packaging: 50mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 017881
Product name: Motesanib
Packaging: 5mg
Price: $496
Updated: 2021/12/16

Adipogen Life Sciences

Product number: SYN-1055-M100
Product name: Motesanib
Purity: ≥95%
Packaging: 100mg
Price: $1069
Updated: 2021/12/16

AK Scientific

Product number: X4931
Product name: Motesanib
Packaging: 500mg
Price: $1265
Updated: 2021/12/16

Matrix Scientific

Product number: 132644
Product name: N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide
Purity: 97%
Packaging: 250mg
Price: $630
Updated: 2021/12/16

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Motesanib Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

Uses

Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.

Definition

ChEBI: Motesanib is a pyridinecarboxamide.

target

VEGFR1

Motesanib Preparation Products And Raw materials

Raw materials

Preparation Products

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Motesanib Suppliers

Canada 1 China 119 Germany 1 India 2 United Kingdom 3 United States 18 Global 144

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

ChemieTek

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Email: info@chemietek.com
Country: United States
ProdList: 219
Advantage: 50

United States Biological

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Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Creative Enzymes

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Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Matrix Scientific

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Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

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View Lastest Price from Motesanib manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: motesanib 453562-69-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

Career Henan Chemical Co

Product: Motesanib 453562-69-1
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kgs
Release date: 2020-01-02

453562-69-1, MotesanibRelated Search:

Xylene Imiquimod Dacthal Dimethyl fumarate N,N-Dimethylformamide Dimethyl carbonate Dimethyl sulfoxide Dimethyl sulfate Dimethyl phthalate Dimethyl ether ETHANE 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE Compound 23 ERK Inhibitor 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID Motesanib

CS-1108

AMG 706; AMG-706

N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide

3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-

Motesanib Base

AMG-706(Motesanib)

Motesanib (AMG-706) Base)

motesanib

N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide

N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide

N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706

D06678

2,4-Imidazolidinedione,5-(3-bromophenyl)-6-methyl-

453562-69-1

API

Inhibitors

Antineoplastic