ChemicalBook > CAS DataBase List > 6-bromoimidazo[1,2-a]pyrazin-8-amine

6-bromoimidazo[1,2-a]pyrazin-8-amine

Application

Product Name: 6-bromoimidazo[1,2-a]pyrazin-8-amine
CAS No.: 117718-84-0
Chemical Name: 6-bromoimidazo[1,2-a]pyrazin-8-amine
Synonyms: PAB 12;2-a]pyrazin-8-aMine;6-bromoimidazo[1,2-a]pyrazin-8-amine;6-bromo-8-imidazo[1,2-a]pyrazinamine;8-bromoimidazo[1,2-a]pyrazin-6-amine;6-Bromo-8-aminoimidazo[1,2-a]pyrazine;8-Amino-6-bromoimidazo[1,2-a]pyrazine;6-Bromoimidazo[1,2-a]pyrazin-8-ylamine;Imidazo[1,2-a]pyrazin-8-amine,6-bromo-
CBNumber: CB01562365
Molecular Formula: C6H5BrN4
Formula Weight: 213.03
MOL File: 117718-84-0.mol

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6-bromoimidazo[1,2-a]pyrazin-8-amine Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: Yellow to brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B701833
Product name: 6-Bromoimidazo[1,2-a]pyrazin-8-amine
Packaging: 100mg
Price: $220
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142646
Product name: 6-Bromoimidazo[1,2-a]pyrazin-8-amine
Packaging: 2g
Price: $256
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: B12903
Product name: 6-Bromoimidazo[1,2-a]pyrazin-8-amine
Purity: 95%
Packaging: 1g
Price: $300
Updated: 2021/12/16

Apolloscientific

Product number: OR300017
Product name: 8-Amino-6-bromoimidazo[1,2-a]pyrazine
Packaging: 1g
Price: $499
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142646
Product name: 6-Bromoimidazo[1,2-a]pyrazin-8-amine
Packaging: 5G
Price: $512
Updated: 2021/12/16

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6-bromoimidazo[1,2-a]pyrazin-8-amine Chemical Properties,Usage,Production

Application

6-bromoimidazo[1,2-a]pyrazin-8-amine are a type of synthetic building block with strong pharmacological activity among nitrogen-containing heterocyclic compounds. Heterocyclic compounds are a class of small molecule compounds with strong biological activity and are widely used in fields such as biomedicine, pesticides, and optoelectronic materials. In particular, 6-haloimidazo[1,2-A]pyrazine active small molecule compounds are a research hotspot for major pharmaceutical companies.

Synthesis

63744-22-9

117718-84-0

General procedure for the synthesis of 6-bromoimidazo[1,2-A]pyrazin-8-amine from 6,8-dibromo-imidazo[1,2-A]pyrazine: The product obtained from the preparation of Example 29 (1.80 g, 6.45 mmol) was mixed with concentrated aqueous NH4OH solution (27.0 mL) in a closed pressure vessel and reacted with stirring for 24 hrs at 90 °C. Upon completion of the reaction, the solvent was removed by evaporation and the resulting residue was purified by silica gel column chromatography with EtOAc as eluent. A white solid product (1.01 g, 73% yield) was finally obtained.LCMS analysis showed that MH+ = 213.

References

[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 18, p. 3353 - 3358
[2] Patent: US2004/63715, 2004, A1. Location in patent: Page/Page column 27
[3] Patent: WO2004/22562, 2004, A1. Location in patent: Page 28

6-bromoimidazo[1,2-a]pyrazin-8-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-bromoimidazo[1,2-a]pyrazin-8-amine manufacturers

Career Henan Chemical Co

Product: 6-bromoimidazo[1,2-a]pyrazin-8-amine 117718-84-0
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-14

117718-84-0, 6-bromoimidazo[1,2-a]pyrazin-8-amineRelated Search:

6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE 6-BROMOIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate 6-Bromo-imidazo[1,2-a]pyrimidine Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate 6-BROMO-THIAZOLO[5,4-B]PYRIDINE 6-Bromoimidazo[1,2-b]pyri... 6-BROMOTHIAZOLO[5,4-B]PYRAZINE 6-bromoH-imidazo[1,2-a]pyridine-2-carboxylic acid 6-Bromoimidazo[1,2-a]pyridine 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE 6-Bromo-2-mercaptothiazolo[4,5-b]pyridine 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID Thiazolo[4,5-b]pyridin-2-aMine, 6-broMo- Imidazo[1,2-a]pyrazin-8-amine (9CI) 6-Bromoimidazo[1,2-a]pyrazine 6-BROMO-8-MORPHOLINOIMIDAZOL[1,2-A]PYRAZINE IMIDAZO[1,2-A]PYRAZINE

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8-Amino-6-bromoimidazo[1,2-a]pyrazine

Imidazo[1,2-a]pyrazin-8-amine,6-bromo-

2-a]pyrazin-8-aMine

8-bromoimidazo[1,2-a]pyrazin-6-amine

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6-Bromoimidazo[1,2-a]pyrazin-8-ylamine

117718-84-0

CHIRAL CHEMICALS