6-bromoimidazo[1,2-a]pyrazin-8-amine
Application- Product Name
- 6-bromoimidazo[1,2-a]pyrazin-8-amine
- CAS No.
- 117718-84-0
- Chemical Name
- 6-bromoimidazo[1,2-a]pyrazin-8-amine
- Synonyms
- PAB 12;2-a]pyrazin-8-aMine;6-bromoimidazo[1,2-a]pyrazin-8-amine;6-bromo-8-imidazo[1,2-a]pyrazinamine;8-bromoimidazo[1,2-a]pyrazin-6-amine;6-Bromo-8-aminoimidazo[1,2-a]pyrazine;8-Amino-6-bromoimidazo[1,2-a]pyrazine;6-Bromoimidazo[1,2-a]pyrazin-8-ylamine;Imidazo[1,2-a]pyrazin-8-amine,6-bromo-
- CBNumber
- CB01562365
- Molecular Formula
- C6H5BrN4
- Formula Weight
- 213.03
- MOL File
- 117718-84-0.mol
6-bromoimidazo[1,2-a]pyrazin-8-amine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Yellow to brown Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B701833
- Product name
- 6-Bromoimidazo[1,2-a]pyrazin-8-amine
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- FB142646
- Product name
- 6-Bromoimidazo[1,2-a]pyrazin-8-amine
- Packaging
- 2g
- Price
- $256
- Updated
- 2021/12/16
- Product number
- B12903
- Product name
- 6-Bromoimidazo[1,2-a]pyrazin-8-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- OR300017
- Product name
- 8-Amino-6-bromoimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $499
- Updated
- 2021/12/16
- Product number
- FB142646
- Product name
- 6-Bromoimidazo[1,2-a]pyrazin-8-amine
- Packaging
- 5G
- Price
- $512
- Updated
- 2021/12/16
6-bromoimidazo[1,2-a]pyrazin-8-amine Chemical Properties,Usage,Production
Application
6-bromoimidazo[1,2-a]pyrazin-8-amine are a type of synthetic building block with strong pharmacological activity among nitrogen-containing heterocyclic compounds. Heterocyclic compounds are a class of small molecule compounds with strong biological activity and are widely used in fields such as biomedicine, pesticides, and optoelectronic materials. In particular, 6-haloimidazo[1,2-A]pyrazine active small molecule compounds are a research hotspot for major pharmaceutical companies.
Synthesis
63744-22-9
117718-84-0
General procedure for the synthesis of 6-bromoimidazo[1,2-A]pyrazin-8-amine from 6,8-dibromo-imidazo[1,2-A]pyrazine: The product obtained from the preparation of Example 29 (1.80 g, 6.45 mmol) was mixed with concentrated aqueous NH4OH solution (27.0 mL) in a closed pressure vessel and reacted with stirring for 24 hrs at 90 °C. Upon completion of the reaction, the solvent was removed by evaporation and the resulting residue was purified by silica gel column chromatography with EtOAc as eluent. A white solid product (1.01 g, 73% yield) was finally obtained.LCMS analysis showed that MH+ = 213.
References
[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 18, p. 3353 - 3358
[2] Patent: US2004/63715, 2004, A1. Location in patent: Page/Page column 27
[3] Patent: WO2004/22562, 2004, A1. Location in patent: Page 28
6-bromoimidazo[1,2-a]pyrazin-8-amine Preparation Products And Raw materials
Raw materials
Preparation Products
6-bromoimidazo[1,2-a]pyrazin-8-amine Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 6-bromoimidazo[1,2-a]pyrazin-8-amine manufacturers
- Product
- 6-bromoimidazo[1,2-a]pyrazin-8-amine 117718-84-0
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-14