ChemicalBook > CAS DataBase List > Metaxalone
Metaxalone
- Product Name
- Metaxalone
- CAS No.
- 1665-48-1
- Chemical Name
- Metaxalone
- Synonyms
- Zorane;AHR-438;Skelaxi;NSC2351;cl39,148;SKELAXIN;NSC 2351;NSC-2351;CL 39,148;Metaxalon
- CBNumber
- CB0175959
- Molecular Formula
- C12H15NO3
- Formula Weight
- 221.25
- MOL File
- 1665-48-1.mol
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Metaxalone Property
- Melting point:
- 121-1230C
- Boiling point:
- 225°C/1.5mmHg(lit.)
- Density
- 1.1514 (rough estimate)
- refractive index
- 1.5200 (estimate)
- Flash point:
- 9 °C
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: ≥2mg/mL (warmed to 60 °C)
- pka
- 12.26±0.40(Predicted)
- form
- powder
- color
- white to tan
- BCS Class
- 2
- InChIKey
- IMWZZHHPURKASS-UHFFFAOYSA-N
- CAS DataBase Reference
- 1665-48-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Metaxalone(1665-48-1)
- EPA Substance Registry System
- 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]- (1665-48-1)
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Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 3
- RTECS
- RQ3850000
- HS Code
- 2934990002
- Hazardous Substances Data
- 1665-48-1(Hazardous Substances Data)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHR3036
- Product name
- Metaxalone
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 500MG
- Price
- $173
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M-074
- Product name
- Metaxalone solution
- Purity
- 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $166
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1396149
- Product name
- Metaxalone
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $174.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M-143
- Product name
- Metaxalone-D6 solution
- Purity
- 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $124
- Updated
- 2022/05/15
TCI Chemical
- Product number
- M2578
- Product name
- Metaxalone
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $39
- Updated
- 2024/03/01
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Metaxalone Chemical Properties,Usage,Production
Chemical Properties
White Crystalline Solid
Originator
Skelaxin,Robins,US,1962
Uses
It is a muscle relaxant used to relax muscles and relieve pain
Uses
muscle relaxant (skeletal)
Uses
For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes.
Uses
Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical]
Definition
ChEBI: Metaxalone is an aromatic ether.
Manufacturing Process
Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C.
Therapeutic Function
Muscle relaxant
Metaxalone Preparation Products And Raw materials
Raw materials
Preparation Products
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Metaxalone Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
- Tel
- --
- Fax
- --
- research@tlcpharmachem.com
- Country
- Canada
- ProdList
- 921
- Advantage
- 60
- Tel
- --
- Fax
- --
- research@synfine.com.
- Country
- Canada
- ProdList
- 768
- Advantage
- 42
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View Lastest Price from Metaxalone manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Metaxalone 1665-48-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Metaxalone 1665-48-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
Career Henan Chemical Co
- Product
- Metaxalone 1665-48-1
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-22
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