Metaxalone

ChemicalBook > CAS DataBase List > Metaxalone

Product Name: Metaxalone
CAS No.: 1665-48-1
Chemical Name: Metaxalone
Synonyms: Zorane;AHR-438;Skelaxi;NSC2351;cl39,148;SKELAXIN;NSC 2351;NSC-2351;CL 39,148;Metaxalon
CBNumber: CB0175959
Molecular Formula: C12H15NO3
Formula Weight: 221.25
MOL File: 1665-48-1.mol

Less

Metaxalone Property

Melting point:: 121-1230C
Boiling point:: 225°C/1.5mmHg(lit.)
Density: 1.1514 (rough estimate)
refractive index: 1.5200 (estimate)
Flash point:: 9 °C
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: ≥2mg/mL (warmed to 60 °C)
pka: 12.26±0.40(Predicted)
form: powder
color: white to tan
BCS Class: 2
InChIKey: IMWZZHHPURKASS-UHFFFAOYSA-N
CAS DataBase Reference: 1665-48-1(CAS DataBase Reference)
NIST Chemistry Reference: Metaxalone(1665-48-1)
EPA Substance Registry System: 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]- (1665-48-1)

Less

Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany: 3
RTECS: RQ3850000
HS Code: 2934990002
Hazardous Substances Data: 1665-48-1(Hazardous Substances Data)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3036
Product name: Metaxalone
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $173
Updated: 2024/03/01

Sigma-Aldrich

Product number: M-074
Product name: Metaxalone solution
Purity: 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1396149
Product name: Metaxalone
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $174.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: M-143
Product name: Metaxalone-D6 solution
Purity: 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $124
Updated: 2022/05/15

TCI Chemical

Product number: M2578
Product name: Metaxalone
Purity: >98.0%(GC)
Packaging: 1g
Price: $39
Updated: 2024/03/01

Less

Metaxalone Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Originator

Skelaxin,Robins,US,1962

Uses

It is a muscle relaxant used to relax muscles and relieve pain

Uses

muscle relaxant (skeletal)

Uses

For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes.

Uses

Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical]

Definition

ChEBI: Metaxalone is an aromatic ether.

Manufacturing Process

Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C.

Therapeutic Function

Muscle relaxant

Metaxalone Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Metaxalone Suppliers

Americas 1 Canada 3 China 136 Europe 3 Germany 1 India 23 Italy 4 Japan 1 South Korea 1 United Kingdom 4 United States 36 Global 213

Nanjing LuoDa Chemical Co., Ltd

Tel: 025-66016961 13382082786
Fax: 025-52204547
Country: China
ProdList: 278
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD.

Tel: 86-029-85456576
Fax: 86-029-85456576-808
Email: daisy_wang@vip.163.com
Country: China
ProdList: 292
Advantage: 55

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4576
Advantage: 55

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1958
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4528
Advantage: 56

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16687
Advantage: 50

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Watson Biotechnology Co.,Ltd

Tel: 027-027-59207879 18140587686
Fax: QQ：1972026995
Email: kf@3600chem.com
Country: China
ProdList: 4699
Advantage: 55

Weifang QianJin Fine Chemical Co., Ltd.

Tel: 0536-2457064 13031698386
Fax: 0536-8897109
Email: 1577399715@qq.COM
Country: China
ProdList: 1691
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Raw material medicin reagent co.,Ltd

Tel: 025-57798860
Email: sales@njromanme.com
Country: China
ProdList: 4534
Advantage: 58

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Shenzhen Simeiquan Biotechnology Co. Ltd

Tel: 18126413629 0755-23311925 2355327053
Fax: 0755-23311925
Email: abel@ycgmp.com
Country: China
ProdList: 5115
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6120
Advantage: 58

Wuhan Wsem Biological Co., Ltd.

Tel: 027-83778876 13667159345
Fax: 027-83778876
Email: 13667159345@163.com
Country: China
ProdList: 1941
Advantage: 55

Wellman Pharmaceutical Group Limited

Tel: 027-027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 3979
Advantage: 58

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9980
Advantage: 55

Shenzhen Newcore Chemical Technology Co., Ltd.

Tel: 13612807752
Email: ncchemical@163.com
Country: China
ProdList: 290
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9974
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19806
Advantage: 60

Hubei widely chemical technology Co., Ltd.

Tel: 027-83778895 18602735115
Fax: 027-51119224
Email: 18602735115@163.com
Country: China
ProdList: 1994
Advantage: 64

Foshan DaoQi Biological Co., Ltd.

Tel: 18062666947
Fax: 18062666959
Email: 2355880548@qq.com
Country: China
ProdList: 4229
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9968
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 6912
Advantage: 58

Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-87576359 17691182729
Fax: 029-88380327
Email: 1018@dideu.com
Country: China
ProdList: 1982
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

Guangzhou Tomums Life Science Co., Ltd.

Tel: 020-31155029 18902330969
Fax: 020-31155029
Email: sales@tomums.cn
Country: China
ProdList: 4698
Advantage: 58

Xi'an MC Biotech, Co., Ltd.

Tel: 029-89275612 +8618991951683
Fax: 8618991951683
Email: mcbio_sales@163.com
Country: China
ProdList: 2255
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: 0551-65418671
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34572
Advantage: 58

Less

View Lastest Price from Metaxalone manufacturers

Shanghai Affida new material science and technology center

Product: Metaxalone 1665-48-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100KG
Release date: 2024-04-15

Zhuozhou Wenxi import and Export Co., Ltd

Product: Metaxalone 1665-48-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Metaxalone 1665-48-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

1665-48-1, MetaxaloneRelated Search:

Bensulfuron methyl Nabumetone Methylparaben Diethoxydimethylsilane N,N-Dimethyldodecylamine Linezolid Poly(dimethylsiloxane) Dimethyl sulfoxide Thiophanate-methyl N,N-Dimethylformamide Methyl acetate Kresoxim-methyl Chlormezanone METSULFURON METHYL Methyl salicylate Metandienone Dimethyldimethoxysilane Methyl

5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one

2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-

2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]-

5-((3,5-dimethylphenoxy)methyl)-2-oxazolidinon

5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone

5-((3,5-xylyloxy)methyl)-2-oxazolidinon

5-((3,5-Xylyloxy)methyl)-2-oxazolidinone

5-(3,5-Xyloloxymethyl)oxazolidin-2-one

5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one

AHR-438

CL 39,148

cl39,148

Metaxalon

Metazalone

Metazolone

Methaxalonum

Methoxolone

Zorane

5-(3,5-xylyloxymethyl)-2-oxazolidone

Metaxalowe

METAXALONE

METAXALONE-D6

METAXOLONE

SKELAXIN

METAXALONE 99.0%

Metaxolene(DCPDAcetate)

Skelaxi

5-[(3,5-Dimethylphenoxy)methyl]oxazolidin-2-one-d6

AHR-438-d6

Skelaxin-d

5-(3,5-Dimethylphenoxy)methyl-2-Oxazolidinone(Metaxalone)

Skelaxin-d6

Metaxalone solution

NSC 170959

Metaxalone-D6 solution

Metaxalone (200 mg)

(5R)-5-(3,5-diMethylphenoxyMethyl)-1,3-oxazolidin-2-one

Metaxalone-D

AHR438;NSC170959;SKELAXIN

Metaxalone &gt

Metaxalone USP/EP/BP

Metaxalone (AHR438

MetaxaloneQ: What is Metaxalone Q: What is the CAS Number of Metaxalone Q: What is the storage condition of Metaxalone Q: What are the applications of Metaxalone

Metaxalone (1396149)

NSC 2351

NSC2351

NSC-2351

Beauty he methadone

Methaxadone

Metaxalone, ≥ 98.0%

1665-48-1

1665-45-1

C12H9D6NO3

SKELAXON

Various Metabolites and Impurities

Metabolites & Impurities

Isotope Labeled Compounds

Isotope Labelled Compounds