Metaxalone

ChemicalBook > CAS DataBase List > Metaxalone

Product Name: Metaxalone
CAS No.: 1665-48-1
Chemical Name: Metaxalone
Synonyms: Zorane;AHR-438;Skelaxi;NSC2351;cl39,148;SKELAXIN;NSC 2351;NSC-2351;CL 39,148;Metaxalon
CBNumber: CB0175959
Molecular Formula: C12H15NO3
Formula Weight: 221.25
MOL File: 1665-48-1.mol

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Metaxalone Property

Melting point:: 121-1230C
Boiling point:: 225°C/1.5mmHg(lit.)
Density: 1.1514 (rough estimate)
refractive index: 1.5200 (estimate)
Flash point:: 9 °C
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: ≥2mg/mL (warmed to 60 °C)
pka: 12.26±0.40(Predicted)
form: powder
color: white to tan
BCS Class: 2
InChIKey: IMWZZHHPURKASS-UHFFFAOYSA-N
CAS DataBase Reference: 1665-48-1(CAS DataBase Reference)
NIST Chemistry Reference: Metaxalone(1665-48-1)
EPA Substance Registry System: 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]- (1665-48-1)

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany: 3
RTECS: RQ3850000
HS Code: 2934990002
Hazardous Substances Data: 1665-48-1(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3036
Product name: Metaxalone
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $173
Updated: 2024/03/01

Sigma-Aldrich

Product number: M-074
Product name: Metaxalone solution
Purity: 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1396149
Product name: Metaxalone
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $174.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: M-143
Product name: Metaxalone-D6 solution
Purity: 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $124
Updated: 2022/05/15

TCI Chemical

Product number: M2578
Product name: Metaxalone
Purity: >98.0%(GC)
Packaging: 1g
Price: $39
Updated: 2024/03/01

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Metaxalone Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Originator

Skelaxin,Robins,US,1962

Uses

It is a muscle relaxant used to relax muscles and relieve pain

Uses

muscle relaxant (skeletal)

Uses

For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes.

Uses

Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical]

Definition

ChEBI: Metaxalone is an aromatic ether.

Manufacturing Process

Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C.

Therapeutic Function

Muscle relaxant

Metaxalone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Metaxalone manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Metaxalone 1665-48-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Metaxalone 1665-48-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

Career Henan Chemical Co

Product: Metaxalone 1665-48-1
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-22

1665-48-1, MetaxaloneRelated Search:

Bensulfuron methyl Nabumetone Methylparaben Diethoxydimethylsilane N,N-Dimethyldodecylamine Linezolid Poly(dimethylsiloxane) Dimethyl sulfoxide Thiophanate-methyl N,N-Dimethylformamide Methyl acetate Kresoxim-methyl Chlormezanone METSULFURON METHYL Methyl salicylate Metandienone Dimethyldimethoxysilane Methyl

5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one

2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-

2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]-

5-((3,5-dimethylphenoxy)methyl)-2-oxazolidinon

5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone

5-((3,5-xylyloxy)methyl)-2-oxazolidinon

5-((3,5-Xylyloxy)methyl)-2-oxazolidinone

5-(3,5-Xyloloxymethyl)oxazolidin-2-one

5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one

AHR-438

CL 39,148

cl39,148

Metaxalon

Metazalone

Metazolone

Methaxalonum

Methoxolone

Zorane

5-(3,5-xylyloxymethyl)-2-oxazolidone

Metaxalowe

METAXALONE

METAXALONE-D6

METAXOLONE

SKELAXIN

METAXALONE 99.0%

Metaxolene(DCPDAcetate)

Skelaxi

5-[(3,5-Dimethylphenoxy)methyl]oxazolidin-2-one-d6

AHR-438-d6

Skelaxin-d

5-(3,5-Dimethylphenoxy)methyl-2-Oxazolidinone(Metaxalone)

Skelaxin-d6

Metaxalone solution

NSC 170959

Metaxalone-D6 solution

Metaxalone (200 mg)

(5R)-5-(3,5-diMethylphenoxyMethyl)-1,3-oxazolidin-2-one

Metaxalone-D

AHR438;NSC170959;SKELAXIN

Metaxalone &gt

Metaxalone USP/EP/BP

Metaxalone (AHR438

MetaxaloneQ: What is Metaxalone Q: What is the CAS Number of Metaxalone Q: What is the storage condition of Metaxalone Q: What are the applications of Metaxalone

Metaxalone (1396149)

NSC 2351

NSC2351

NSC-2351

Beauty he methadone

Methaxadone

Metaxalone, ≥ 98.0%

Skelaxin|||Methaxalonum|||Zorane|||NSC170959|||AHR438

1665-48-1

1665-45-1

C12H9D6NO3

SKELAXON

Various Metabolites and Impurities

Metabolites & Impurities

Isotope Labeled Compounds