Veratric Acid

Product Name: Veratric Acid
CAS No.: 93-07-2
Chemical Name: Veratric Acid
Synonyms: VERATRIC ACID;NSC 7721;AKOS 220-15;reratric acid;VERATRIC ACID(RG);AKOS BBS-00003717;Veratrumenoic acid;Veratric acid (8CI);RARECHEM AL BO 0042;DiMethoxybenzoic aci
CBNumber: CB0176264
Molecular Formula: C9H10O4
Formula Weight: 182.17
MOL File: 93-07-2.mol

More

Less

Veratric Acid Property

Melting point:: 179-182 °C(lit.)
Boiling point:: 275.56°C (rough estimate)
Density: 1.2481 (rough estimate)
refractive index: 1.4500 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: 0.5g/l
pka: 4.35±0.10(Predicted)
form: Crystalline Powder
color: Almost white to beige or reddish
Water Solubility: slightly soluble
Merck: 14,9953
BRN: 518285
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: DAUAQNGYDSHRET-UHFFFAOYSA-N
LogP: 1.610
CAS DataBase Reference: 93-07-2(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 3,4-dimethoxy-(93-07-2)
EPA Substance Registry System: Benzoic acid, 3,4-dimethoxy- (93-07-2)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: DG8598750
TSCA: Yes
HS Code: 29189090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D131806
Product name: 3,4-Dimethoxybenzoic acid
Purity: ≥99%
Packaging: 100g
Price: $86.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.45140
Product name: 3,4-Dimethoxybenzoic acid
Purity: Msynth?plus
Packaging: 250G
Price: $179
Updated: 2022/05/15

Sigma-Aldrich

Product number: 8.45140
Product name: 3,4-Dimethoxybenzoic acid
Purity: Msynth?plus
Packaging: 1KG
Price: $575
Updated: 2022/05/15

TCI Chemical

Product number: D0631
Product name: 3,4-Dimethoxybenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: D0631
Product name: 3,4-Dimethoxybenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $197
Updated: 2024/03/01

More

Less

Veratric Acid Chemical Properties,Usage,Production

Description

Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits and has antioxidant and anti-inflammatory activities. It also acts as a protective agent against hypertension-associated cardiovascular remodeling. Veratric acid reduces upregulated COX-2 expression and levels of PGE2 and IL-6 after UVB irradiation. This compound could be reduced to veratrine aldehyde, and alcohol was performed with enzyme extracts from a wood-degrading basidiomycete, Polystictus (Trametes) versicolor[1].

Chemical Properties

white to slightly yellow powder

Uses

3,4-Dimethoxybenzoic acid plays an important role in producing antibiotics and various dyes. They are used as intermediates for pharmaceuticals (especially for antipyretic analgesic, antirheumatism) and other organic synthesis. It is used as matrix for ionization of peptides, proteins and carbohydrates.

Uses

3,4-Dimethoxybenzoic acid is a derivative of Protocatechuic Acid.3,4-Dimethoxybenzoic acid is a reagent used in the production of antimicrobial agents, antifeedants, and a variety of other biologically active compounds.

Definition

ChEBI: A member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 26, p. 299, 1978 DOI: 10.1248/cpb.26.299
Tetrahedron Letters, 43, p. 4985, 2002 DOI: 10.1016/S0040-4039(02)00929-2

in vitro

Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation, and HDAC3 expression in RAW264.7 cells.
Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.
Veratric acid reduces upregulated COX-2 expression and levels of PGE2, and IL-6 after UVB irradiation.

Purification Methods

Crystallise the acid from Et2O, H2O or aqueous acetic acid. It has m 180-181o after sublimation at 80o/1mm. [Beilstein 10 H 393, 10 I 188, 10 II 261, 10 III 1404, 10 IV 1406.]

References

[1] Gross, Georg G. “From lignins to tannins: Forty years of enzyme studies on the biosynthesis of phenolic compounds.” Phytochemistry 69 18 (2008): Pages 3018-3031.

Veratric Acid Preparation Products And Raw materials

Raw materials

Preparation Products

5,6-DIMETHOXYISOBENZOFURAN-1(3H)-ONE

More

Less

Veratric Acid Suppliers

Americas 1 Belgium 1 Canada 1 China 457 China Hong Kong 1 Czech Republic 1 Europe 4 France 4 Germany 6 India 82 Japan 7 Slovakia 1 South Korea 1 Switzerland 4 Ukraine 2 United Kingdom 13 United States 61 USA 1 Global 648

Beijing Century Richap Chemistry Co., Ltd.

Tel: 010-64446226
Fax: +86 10 64455595
Email: info@bj-newcenturychem.com
Country: China
ProdList: 111
Advantage: 55

Nanjing Tianyi Chemical Technology Co., Ltd

Tel: 15150528611
Fax: 151-5052-8611
Email: 779881375@qq.com
Country: China
ProdList: 68
Advantage: 58

Beijing Leaderherb Bio-Tech. Co., LTD.

Tel: 010-010-51288246
Email: 300abc@sina.com
Country: China
ProdList: 68
Advantage: 58

Changzhou Zeyuan Pharmaceutical Technology Co., Ltd

Tel: 190-26388314 19015480862
Email: 2589694173@qq.com
Country: China
ProdList: 255
Advantage: 58

Hubei huizepu Pharmaceutical Technology Co., Ltd

Tel: 027-19371-3712 19371278702
Fax: QQ：2462856504
Email: n17762444226@163.com
Country: China
ProdList: 3004
Advantage: 58

Zibo Run Hang Seng material Technology Co., LTD

Tel: 13561657928 13561657928
Email: 2388773670@qq.com
Country: China
ProdList: 303
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

More

Less

View Lastest Price from Veratric Acid manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: 3,4-Dimethoxybenzoic acid 93-07-2
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-05-14

Jinan Finer Chemical Co., Ltd

Product: 3,4-Dimethoxybenzoic acid 93-07-2
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%
Supply Ability: 100mt/year
Release date: 2021-07-08

Hebei Weibang Biotechnology Co., Ltd

Product: 3,4-Dimethoxybenzoic acid 93-07-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-10-31

93-07-2, Veratric AcidRelated Search:

3-Methoxybenzoic acid 2-Methoxybenzoic acid 2,6-Dimethoxybenzaldehyde Dimethoxymethane Folic acid 1,1-Dimethoxyethane Glycine Dimethyldimethoxysilane Citric acid Ethyl 2-(Chlorosulfonyl)acetate 4-Methoxybenzoic acid Diphenyldimethoxysilane 4-[2-(DIMETHYLAMINO)ETHOXY]BENZONITRILE Itopride N-Oxide ETHYL 3,4-DIMETHOXYBENZOATE 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE 3,4-DIMETHOXYBENZOYL CHLORIDE Ascoric Acid Veratric Acid

NSC 7721

Protocatechuic Acid Dimethyl Ether Veratric Acid

(2R)-2,7,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol

3,4-DiMethoxybenzoic acid, 99+% 100GR

3,4-DIMETHOXYBENZOIC ACID FOR SYNTHESIS

DiMethoxybenzoic aci

3,4- twoMethoxybenzoic acid

3,4-DIMETHOXYBENZOIC ACID (VERATRIC ACID)

3,4-Bis(methyloxy)benzoic acid

Veratric acid (8CI)

3,4-DIMETHOXYBENZOIC ACID, 99+%

3,4-DIMETHOXYENZIOC ACID

3,4-DimethoxbenzoicAcid99%

3,4-Dimethoxybenzoic

Benzoic acid, 3,4-dimethoxy-

VERATRIC ACID(RG)

reratric acid

3,4-DIMETHOXY BENZOIC ACID (VERATRIC ACID) ,99+%

3,4-Dimethoxybenzoic acid≥ 99% (Titration)

DIMETHYLPROTOCATECHUIC ACID

RARECHEM AL BO 0042

PROTOCATECHUIC ACID DIMETHYL ETHER

3,4-DIMETHOXYBENZOIC ACID

AKOS 220-15

AKOS BBS-00003717

VERATRIC ACID

3,4-dimethoxy-benzoicaci

3,4-Dimethylprotocatechuic acid

3,4-dimethylprotocatechuicacid

Veratrumenoic acid

3,4-Dimethoxybenzoic Acid &gt

3,4-Dimethoxybenzoic Acid (Veratric

Mebeverine Impurity D

Itopride Impurity 15

Mebeverine EP Impurity D

3,4-Dimethoxy benzoic acid (Veratric acid- 98%)

Veratric acid（3,4-Dimethoxybenzoic acid）

3,4-Dimethoxybenzoic acid CAS：93-07-2

Mebeverine Hydrochloride Impurity D

Mebeverine Hydrochloride EP Impurity D

VERATRIC ACID ITOPRIDE/MEBEVERINE

Resulinic acid (3, 4-dimethoxybenzoic acid)

93-07-2

1993-7-2

93-7-2

1993-07-2

193-07-2

34152

CAS:1993-07-2

CH3O2C6H3COOH

CH3O2C6H3CO2H

Building Blocks

C9

Carboxylic Acids

Carbonyl Compounds

Organic Building Blocks

intermediate

Aromatics