AMASTATIN HYDROCHLORIDE

Product Name: AMASTATIN HYDROCHLORIDE
CAS No.: 100938-10-1
Chemical Name: AMASTATIN HYDROCHLORIDE
Synonyms: AMASTATIN;AMASTATIN HCL;AMASTATIN HYDROCHLORIDE;AMASTATIN HYDROCHLORIDE HYDRATE;H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL;Amastatin hydrate hydrochloride;4-formylphenyl-O-β-d-allopyranoside;N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&;Amastatinhydrochloridebiochemikasynthetic;(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL
CBNumber: CB0194817
Molecular Formula: C21H39ClN4O8
Formula Weight: 511.01
MOL File: 100938-10-1.mol

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AMASTATIN HYDROCHLORIDE Property

Melting point:: 202-205 °C
storage temp.: -20°C
solubility: methanol: 5 mg/mL, clear, colorless
form: White to off-white powder.
color: White to off-white
BRN: 8888370

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Safety

WGK Germany: 3
F: 10
HS Code: 2924190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A1276
Product name: Amastatin hydrochloride hydrate
Purity: ≥97% (HPLC)
Packaging: 0.5mg
Price: $177
Updated: 2024/03/01

Sigma-Aldrich

Product number: A1276
Product name: Amastatin hydrochloride hydrate
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $282
Updated: 2024/03/01

Cayman Chemical

Product number: 16719
Product name: Amastatin (hydrochloride)
Purity: ≥95%
Packaging: 500μg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 16719
Product name: Amastatin (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $60
Updated: 2024/03/01

Sigma-Aldrich

Product number: A1276
Product name: Amastatin hydrochloride hydrate
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $1010
Updated: 2024/03/01

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AMASTATIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.[Cayman Chemical]

General Description

Chemical structure: peptide

Biochem/physiol Actions

It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.

storage

+4°C

AMASTATIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMASTATIN HYDROCHLORIDE Suppliers

China 74 Europe 1 Germany 3 Switzerland 1 United Kingdom 5 United States 14 USA 1 Global 99

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Beijing NuoqiYa Biotechnology Co., Ltd.

Tel: 4000-819-385 010-62329685 13718666987
Fax: 010-62340519
Country: China
ProdList: 1971
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

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View Lastest Price from AMASTATIN HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: AMASTATIN HYDROCHLORIDE 100938-10-1
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

100938-10-1, AMASTATIN HYDROCHLORIDERelated Search:

N-(2-AMINOETHYL)-L-ASPARTIC ACID GLYCYLGLYCINE HYDROCHLORIDE L-Homoserine L-Aspartic acid hydrochloride D-Leucinol H-VAL-NH2 HCL 1,3-Diamino-2-propanol H-BETA-ALA-NH2 HCL (R)-HOMO-BETA-ALANINE HYDROCHLORIDE H-VAL-ASP-OH AC-VAL-NHME H-ALA-ALA-NH2 HCL AC-VAD-CHO (S)-(-)-LACTAMIDE H-VAL-BETA-ALA-OH BETA-HOMOALANINE HYDROCHLORIDE AMASTATIN,AMASTATIN, STREPTOMYCES SPECIES H-ALA-VAL-NH2 HCL

[(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP HYDROCHLORIDE

(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL

AMASTATIN

AMASTATIN HCL

AMASTATIN HYDROCHLORIDE

AMASTATIN HYDROCHLORIDE HYDRATE

H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL

N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&

Amastatinhydrochloridebiochemikasynthetic

(2s,3r)-3-amino-2-hydroxy-5-methylhexanoyl-val-val-asp hydrochloride hydrate

(Amino-2-hydroxy-5-methyl-hexanoyl)-L-valyl-L-valyl-L-aspartic acid hydrochloride salt

(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrate hydrochloride

Amastatin hydrate hydrochloride

L-Aspartic acid,N-[(2S,3R)-3-amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-,monohydrochloride (9CI)

4-formylphenyl-O-β-d-allopyranoside

100938-10-1

C21H38N4O8HCl

C21H38N4O8HClxH2O

C21H38N4O8ClH

BioChemical

Antibiotics

Antibiotics A to Z

Antibiotics A-F

peptides

inhibitor

Pepetides