Formoterol fumarate dihydrate

Product Name: Formoterol fumarate dihydrate
CAS No.: 183814-30-4
Chemical Name: Formoterol fumarate dihydrate
Synonyms: Formoterol fumarate dihydrate;Unii-W34shf8J2k;Formoterol hemifumar;forMaMide fuMarate dihydrate;Formoterol Fumarate (100 mg);Formoterol fumarate 2-hydrate;Arformoterol Fumarate Dihydrate;Formoterol Hemifumarate Dihydrate;Formoterol hemifumarate monohydrate;Formoterol fumarate dihydrate, >=99%
CBNumber: CB02130563
Molecular Formula: C23H28N2O8
Formula Weight: 460.48
MOL File: 183814-30-4.mol

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Formoterol fumarate dihydrate Property

Melting point:: 116-120°C
storage temp.: 2-8°C
solubility: DMSO: soluble20mg/mL
form: solid
color: white to off-white
InChIKey: RATSWNOMCHFQGJ-XODSYJLDSA-N
SMILES: C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 |&1:8,22,r|
CAS DataBase Reference: 183814-30-4

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Safety

RIDADR: UN 2811 6.1 / PGII
WGK Germany: 3
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H332Harmful if inhaled

H370Causes damage to organs

H373May cause damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F9552
Product name: Formoterol fumarate dihydrate
Purity: >98% (HPLC)
Packaging: 10mg
Price: $221
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2703
Product name: Formoterol fumarate
Purity: PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial,certifiedrefer
Packaging: 500MG
Price: $400
Updated: 2024/03/01

Sigma-Aldrich

Product number: F0372000
Product name: Formoterol fumarate dihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10mg
Price: $181
Updated: 2022/05/15

Sigma-Aldrich

Product number: F9552
Product name: Formoterol fumarate dihydrate
Purity: >98% (HPLC)
Packaging: 50mg
Price: $761
Updated: 2024/03/01

Sigma-Aldrich

Product number: F0372000
Product name: Formoterol fumarate dihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: f0372000
Price: $153
Updated: 2024/03/01

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Formoterol fumarate dihydrate Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Formoterol is a selective β2-adrenergic receptor agonist. Formoterol is used as an antiasthmatic.

Uses

ForMoterol FuMarate Dihydrate is a selective β2-adrenergic receptor agonist,it is used as an antiasthmatic.

Biological Activity

Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.

Biochem/physiol Actions

β2-Adrenoreceptor agonist.

Drug interactions

The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].

References

[1] Aagaard, Lise . "A worldwide yearly survey of new data in adverse drug reactions." (2014).

Formoterol fumarate dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Formoterol fumarate dihydrate Suppliers

Canada 1 China 170 Finland 1 India 20 Israel 1 Italy 5 Spain 1 United Kingdom 3 United States 10 USA 1 Global 213

Shandong Risen-Sun Pharmaceutical Co., Ltd

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View Lastest Price from Formoterol fumarate dihydrate manufacturers

Sinoway Industrial co., ltd.

Product: Formoterol Fumarate Dihydrate 183814-30-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20TONS
Release date: 2024-12-23

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Formoterol Fumarate Monohydrate/ dihydrate 183814-30-4
Price: US $0.00/g/Bag
Min. Order: 10g
Purity: 98.5%min; JP14
Supply Ability: 20kg/month
Release date: 2021-06-03

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Formoterol Fumarate Dihydrate 183814-30-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 TONS
Release date: 2022-11-07

183814-30-4, Formoterol fumarate dihydrateRelated Search:

CHLOROPHOSPHONAZO III Chlorantraniliprole 1-Hydroxyethylidene-1,1-diphosphonic acid Arformoterol tartrate Fumaric acid Dimethyl fumarate Formoterol Ketotifen fumarate Benzamide 4-Ethyl-5-fluoro-6-hydroxypyrimidine N,N-Dimethylformamide Formamide Ferrous fumarate Formoterol fumarate FOROXYMITHINE FUMARATE Formoterol fumarate dihydrate

Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-, (2E)-2-butenedioate (2:1) (salt), dihydrate

Unii-W34shf8J2k

(±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate

Formoterol fumarate dihydrate ,98.5%

(r*,r*)-n-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate

Formoterol fumarate dihydrate

Formoterol Fumarate (100 mg)

forMaMide fuMarate dihydrate

N-(2-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide fuMarate dihydrate

Formoterol fumarate dihydrate, >=99%

(R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrateChemicalBook

R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate

Formoterol hemifumarate monohydrate

Formoterol fumarate dihydrate Solution in Methanol, 100μg/mL

Formoterol Fumarate Monohydrate/ dihydrate

Formoterol hemifumar

Formoterol fumarate dihydrateQ: What is Formoterol fumarate dihydrate Q: What is the CAS Number of Formoterol fumarate dihydrate Q: What is the storage condition of Formoterol fumarate dihydrate

Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate

Formoterol fumarate 2-hydrate

Formoterol hemifumarate salt monohydrate

Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate

Arformoterol Fumarate Dihydrate

Formoterol Hemifumarate Dihydrate

C13919000 FormoteroLfumaratEdihydrate

183814-30-4

183818-30-4

C19H24N2O4189C4H4O4

C23H32N2O10

C42H52N4O122H2O

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