ChemicalBook > CAS DataBase List > 2,5-Difluoronitrobenzene

2,5-Difluoronitrobenzene

Product Name: 2,5-Difluoronitrobenzene
CAS No.: 364-74-9
Chemical Name: 2,5-Difluoronitrobenzene
Synonyms: 1,4-DIFLUORO-2-NITROBENZENE;AKOS BBS-00006468;2,5-Difluoronitroben;3,5-diflurobenzalcohol;2,5-Difluotonitrobenzene;2,5-DIFLUORONITROBENZENE;1,4-difluoro-2-nitro-benzen;2,5-Difluoro-1-nitrobenzene;2,5-Difluoronitrobenzene98%;1-Nitro-2,5-difluorobenzene
CBNumber: CB0219938
Molecular Formula: C6H3F2NO2
Formula Weight: 159.09
MOL File: 364-74-9.mol

Less

2,5-Difluoronitrobenzene Property

Melting point:: -11.7 °C (lit.)
Boiling point:: 206.5 °C (lit.)
Density: 1.467 g/mL at 25 °C (lit.)
refractive index: n20/D 1.509(lit.)
Flash point:: 194 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
color: Clear yellow
Specific Gravity: 1.467
Water Solubility: insoluble
BRN: 2210200
InChI: InChI=1S/C6H3F2NO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H
InChIKey: XNJAYQHWXYJBBD-UHFFFAOYSA-N
SMILES: C1(F)=CC=C(F)C=C1[N+]([O-])=O
CAS DataBase Reference: 364-74-9(CAS DataBase Reference)
NIST Chemistry Reference: 2,5-Difluoronitrobenzene(364-74-9)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 2810
WGK Germany: 3
RTECS: CZ5715000
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29049090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196622
Product name: 2,5-Difluoronitrobenzene
Purity: 97%
Packaging: 25g
Price: $42.6
Updated: 2025/07/31

TCI Chemical

Product number: D1700
Product name: 2,5-Difluoronitrobenzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $141
Updated: 2025/07/31

TRC

Product number: D447738
Product name: 2,5-Difluoronitrobenzene
Packaging: 500mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC2860
Product name: 2,5-Difluoronitrobenzene
Purity: 98%
Packaging: 50g
Price: $24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4654-3-08
Product name: 2,5-Difluoronitrobenzene
Purity: 98%
Packaging: 25g
Price: $25
Updated: 2021/12/16

Less

2,5-Difluoronitrobenzene Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

2,5-Difluoronitrobenzene was used in the synthesis of :

N-alkylated 2-arylaminobenzimidazoles
quinoxalinones
N-(2-nitro-4-fluorophenyl)-l,2,3,4-tetrahydroisoquinoline

Synthesis

98-95-3

402-67-5

369-34-6

364-74-9

350-46-9

1493-27-2

GENERAL STEPS: In a FEP or PFA reactor fitted with a PTFE-lined magnetic stir bar and connected to a gas scrubber bottle, substituted benzene (0.95-1.10 mmol), 1,1,1,3,3-pentafluorobutane (2 mL per mL of C6H5R), and BF3-Et2O (1.3-1.5 mmol/mmol C6H5R) were added. The mixture was stirred at 0-5 °C (ice bath) for 10-15 min, followed by batchwise addition of XeF2 (1.2-1.3 mmol/mmol C6H5R). After each addition, the mixture was stirred at 22-25 °C for 3-5 min and recooled. After the addition was completed, the dark solution was continued to be stirred at 22-25 °C for 15-30 min. At the end of the reaction, the reaction was quenched by the addition of 10% aqueous KHCO3, the upper organic layer was separated and filtered through a short column packed with silica gel (40-60 μm) and subsequently dried with magnesium sulfate. The final products were analyzed by 19F NMR and GC/MS. The major products are listed in the table and the others are as follows (with GC/MS data).

References

[1] Russian Journal of Organic Chemistry, 2016, vol. 52, # 10, p. 1400 - 1407
[2] Zh. Org. Khim., 2016, vol. 52, # 10, p. 1412 - 1419,8

2,5-Difluoronitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2,5-Difluoronitrobenzene Suppliers

Americas 1 Belgium 2 China 242 Europe 6 France 1 Germany 5 India 7 Italy 1 Japan 5 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 13 United States 42 Global 334

Nantong Haigine Pharma Technology Co., Ltd

Tel: 00-0513-86266699-8010 19040080082
Fax: QQ1355175393
Email: sales@haigine.com
Country: China
ProdList: 64
Advantage: 58

Zhejiang Xieshi New Materials Co., Ltd.,

Tel: 15715833231
Email: sales09@xieshichem.com
Country: China
ProdList: 183
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Shanghai Na Qian Chemical Technology Co. Ltd.

Tel: 13598610367
Fax: QQ:2468833170
Email: 2841375912@qq.com
Country: China
ProdList: 2788
Advantage: 52

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Less

View Lastest Price from 2,5-Difluoronitrobenzene manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2,5-Difluoronitrobenzene 364-74-9
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-08

Shaanxi Dideu Medichem Co. Ltd

Product: 2,5-Difluoronitrobenzene 364-74-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20T
Release date: 2024-06-11

Honest Joy Holdings Limited

Product: 2,5-Difluoronitrobenzene 364-74-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.5%
Supply Ability: 100 tons
Release date: 2022-02-18

364-74-9, 2,5-DifluoronitrobenzeneRelated Search:

4-Fluoronitrobenzene 2,4-Dinitrophenylhydrazine 1-Fluoro-2-nitrobenzene 1,4-DIFLUORO-2-METHYL-5-NITROBENZENE 2,3,4,6-TETRAFLUORONITROBENZENE PENTAFLUORONITROBENZENE 2,6-DIFLUORONITROBENZENE Nitrobenzene 3,4-DIFLUORONITROBENZENE 1,3-Dinitrobenzene 3,5,6-Trifluoro-2-nitroaniline 2,3,4,5-TETRAFLUORO-6-NITROBENZOIC ACID 1,2,4-Trifluoro-5-nitrobenzene 4-BROMO-2,5-DIFLUORONITROBENZENE 2,5-Difluoro-4-nitrobenzoic acid 2,3,4,5-Tetrafluoronitrobenzene 3-CHLORO-2,4-DIFLUORONITROBENZENE 2,3,5,6-TETRAFLUORONITROBENZENE

1,4-difluoro-2-nitro-benzen

Benzene, 1,4-difluoro-2-nitro-

1,4-DIFLUORO-2-NITROBENZENE

2,5-DIFLUORONITROBENZENE

2, 5 - two fluorine nitrobenzene

2,5-Difluotonitrobenzene

AKOS BBS-00006468

2,5-Difluoro-1-nitrobenzene

Benzene, 1,4-difluoro-2-nitro- (6CI,7CI,8CI,9CI)

3,5-diflurobenzalcohol

2,5-Difluoronitrobenzene 98%

2,5-Difluoronitrobenzene98%

1-Nitro-2,5-difluorobenzene

2,5-Difluoronitrobenzene,99%

2,5-Difluoronitroben

2,5-Difluoronitrobenzene &gt

2,5-Difluoronitrobenzene ISO 9001：2015 REACH

high quality 2,5-Difluoronitrobenzene

364-74-9

Nitrogen Compounds

Organic Building Blocks

Nitro Compounds

Building Blocks

Fluorine series

HALIDE

Anilines, Aromatic Amines and Nitro Compounds

Miscellaneous