Tris(2-aminoethyl)amine

Product Name: Tris(2-aminoethyl)amine
CAS No.: 4097-89-6
Chemical Name: Tris(2-aminoethyl)amine
Synonyms: TREN;TAEA;tri(2-aminoethyl)amine;tris(aminoethyl)amine;trenhp;Tris(2-aminoethyL;Tris(2-aMinoethyl)a;Trientine Impurity 5;Triaminotriethyl-amine;N1,N1-Bis(2-aminoethyl)
CBNumber: CB0235693
Molecular Formula: C6H18N4
Formula Weight: 146.23
MOL File: 4097-89-6.mol

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Tris(2-aminoethyl)amine Property

Melting point:: -16 °C
Boiling point:: 114 °C/15 mmHg (lit.)
Density: 0.976 g/mL at 20 °C (lit.)
vapor density: 5 (vs air)
vapor pressure: 0.02 mm Hg ( 20 °C)
refractive index: n20/D 1.497(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), DMSO (Slightly)
form: saline suspension
pka: 10.00±0.10(Predicted)
color: Clear yellow
Specific Gravity: 0.977
Water Solubility: Miscible with water.
Sensitive: Hygroscopic
BRN: 1739626
Stability:: Stable. Hygroscopic. Absorbs carbon dioxide from the air. Incompatible with strong acids, strong oxidizing agents.
CAS DataBase Reference: 4097-89-6(CAS DataBase Reference)
EPA Substance Registry System: 1,2-Ethanediamine, N,N-bis(2-aminoethyl)- (4097-89-6)

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Safety

Hazard Codes: T,Xi
Risk Statements: 22-24-34-36/37/38-10
Safety Statements: 26-36/37/39-45-16
RIDADR: UN 2922 8/PG 2
WGK Germany: 3
RTECS: KH8587082
F: 3-10-23
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29211990
Toxicity: mouse,LD50,oral,1800mg/kg (1800mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONBEHAVIORAL: ATAXIAGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA","Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 223, 1999.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 225630
Product name: Tris(2-aminoethyl)amine
Purity: 96%
Packaging: 10ml
Price: $54.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 225630
Product name: Tris(2-aminoethyl)amine
Purity: 96%
Packaging: 100ml
Price: $266
Updated: 2024/03/01

TCI Chemical

Product number: T1243
Product name: Tris(2-aminoethyl)amine
Purity: >98.0%(T)
Packaging: 5mL
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: T1243
Product name: Tris(2-aminoethyl)amine
Purity: >98.0%(T)
Packaging: 25mL
Price: $105
Updated: 2024/03/01

Alfa Aesar

Product number: B21789
Product name: Tris(2-aminoethyl)amine, 97%
Packaging: 25g
Price: $75.6
Updated: 2024/03/01

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Tris(2-aminoethyl)amine Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

Tris(2-aminoethyl)amine is a tetradentate chelating ligand and forms stable complexes with transition metals. It is also used as a carbon dioxide absorbent. Further, it acts as a reagent for cleavage of the fluorenylmethyloxycarbonyl (Fmoc) group in peptide synthesis. It reacts with aryl isocyanates and isothiocyanates to give tris-urea and -thiourea derivatives.

Definition

ChEBI: Tris(2-aminoethyl)amine is a tetramine.

General Description

Tris(2-aminoethyl)amine (TREN) is a water soluble tripodal ligand that is majorly used in co-ordination chemistry. It has three aminoethylgroups that attach with the surface atoms to provide a scaffold assembly.

Reactivity Profile

Tris(2-aminoethyl)amine (tren) is a commercially available tripodal amine, which has found wide application as a ligand in the preparation of metal complexes. Due to the tripodal arrangement of donor atoms, tren and various N-functionalised derivatives have been commonly employed in the preparation of trigonal bipyramidal metal complexes. More elaborate or extended tren ligands have been formed via substitution or condensation reactions with aldehydes. Metal complexes prepared therefrom have been employed in catalysis and oxygen binding studies. They have also been used to stabilise redox active oxoanions, such as thiosulfate, and to prepare cyano-bridged heteropolynuclear clusters with ferromagnetic properties. Less well explored are aryl-substituted tren ligand structures. However, some have been employed in the formation of transition metal amido complexes, which have been demonstrated to act as catalysts in dinitrogen reduction (Mo V and Cr complexes) and which have been tested in alkene epoxidation reactions (Fe and Mn complexes). Aryl-substituted tren-based ligands are generally synthesised via aryl substitution reactions using commercially available ArF compounds in 28– 99% yields. A different pathway to these aryl-substituted tren compounds involves Pd-mediated aromatic coupling, limited to commercially available ArBr compounds, affording the products 27–90% yields. More extended tren structures have been prepared via a two-step synthesis of the starting ArBr compound followed by Pd-mediated aromatic coupling in lower but acceptable overall yields of 36–45%. Given the versatility and demonstrated utility of these ligands, considerable benefit would be derived from new synthetic strategies that would broaden the range of accessible aryl-substituted tren ligands[2].

Hazard

A poison by ingestion and skin contact.

Safety Profile

A poison by ingestion and skin contact. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

For a separation from a mixture containing 62% TRIEN, see entry under triethylenetetramine. Also purify it by conversion to the hydrochloride (see below), recrystallise it and regenerate the free base [Xie & Hendrickson J Am Chem Soc 109 6981 1987]. [Beilstein 4 H 256, 4 II 695, 4 III 545, 4 IV 1250.]

References

[1] Bengang Zhang. “Highly Branched Tannin-Tris(2-aminoethyl)amine-Urea Wood Adhesives.” Polymers 15 4 (2023).
[2] Ann Almes?ker . “One-pot synthesis of tripodal tris(2-aminoethyl)amine derivatives from seven molecular components.” Tetrahedron Letters 50 16 (2009): Pages 1847-1850.

Tris(2-aminoethyl)amine Preparation Products And Raw materials

Raw materials

Congo Red Sodium hypochlorite Ammonium hydroxide Acrylamide 1,2-Dichloroethane Hydrochloric acid Methanol Sodium hydroxide

Preparation Products

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Tris(2-aminoethyl)amine Suppliers

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View Lastest Price from Tris(2-aminoethyl)amine manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: TRIS(2-AMINOETHYL)AMINE 4097-89-6
Price: US $500.00/bag
Min. Order: 1bag
Purity: 0.99
Supply Ability: 1TON
Release date: 2024-12-03

Shaanxi Dideu New Materials Co. Ltd

Product: TRIS(2-AMINOETHYL)AMINE 4097-89-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2024-11-19

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: TRIS(2-AMINOETHYL)AMINE 4097-89-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.8
Supply Ability: 10000kg
Release date: 2023-08-15

4097-89-6, Tris(2-aminoethyl)amineRelated Search:

Tris(m-methylanilino)melamine Tropine-3-thiol hydrochloride 1-(2-(5-(DIMETHYLAMINO)-1-NAPTHALENESULFONAMIDO)ETHYL)-1,4,7,10-TETRAAZACYCLODODECANE, TETRAHYDROCHLORIDE, DIHYDRATE Aspoxicillin Draflazine 2,8,9-TRIMETHYL-2,5,8,9-TETRAAZA-1-PHOSPHABICYCLO[3.3.3]UNDECANE CYCLEN-GLYOXAL TRIS(2-AMINOETHYL)AMINE TRIS(2-AMINOETHYL)AMINE POLYMER-BOUND,TRIS(2-AMINOETHYL)AMINE, POLYMER-SUPPORTED Ethylenediamine TRIS(2-(ISOPROPYLAMINO)ETHYL)AMINE DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL (DISULFIDE BRIDGE: 2-7) 2,8,9-Tri-i-butyl-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OH (DISULFIDE BRIDGE: 2-7) TRIS(2-DIMETHYLAMINOETHYL)AMINE N,N,N'-tris(2-aminoethyl)ethylenediamine TRIS(2-(METHYLAMINO)ETHYL)AMINE 97 2,8,9-TRI-I-PROPYL-2,5,8,9-TETRAAZA-1-PHOSPHABICYCLO[3.3.3]UNDECANE

tris(aminoethyl)amine

tris(beta-aminoethyl)amine

2,2',2''-Triaminotriethylamine,97%TREN

2,2'',2 -TRIAMINOTRIETHYLAMINE TREN

2,2μ,2μμ-Nitrilotriethylamine, 2,2μ,2μμ-Triaminotriethylamine, TAEA

2,2',2''-Nitrilotris(ethane-1-amine)

2,2',2''-Nitrilotrisethanamine

Tris(2-aminoethyl)amine ,95%

Tris(2-aMinoethyl)aMine, 96% 100ML

Tris(2-aMinoethyl)aMine, 96% 5ML

Tris(2-aminoethyl)amine,96%

Tris(2-aMinoethyl)a

Tris(2-aMinoethyl)aMine 96%

N1,N1-Bis(2-aminoethyl)

TAEA

TRIS(2-AMINOETHYL)AMINE

TREN

2,2',2''-TRIAMINOTRIETHYLAMINE

2,2',2''-NITRILOTRIETHYLAMINE

N1,N1-Bis-(2-amino-ethyl)-ethane-1,2-diamine

nitrilotris(ethylamine)

trenhp

tri(2-aminoethyl)amine

Triaminotriethyl-amine

2,2',2''-Triaminotriethylamine, min. 98% TREN

2,2’,2’’-nitrilotris(ethylamine)

2,2’,2’’-triaminotris(ethylamine)

4-(2-Aminoethyl)diethylene triamine

4-(2-aminoethyl)-diethylenetriamin

4-(2-Aminoethyl)diethylenetriamine

beta,beta’,beta’’-triaminotriethylamine

Tris(2-aminoethyL

1,2-Ethanediamine, N1,N1-bis(2-aminoethyl)-

Trientine Impurity 5

Tris(2-aminoethyl)amine, 98+%,

4097-89-6

C6H18N4

NCH2CH2NH23

NH2CH2CH23N

Building Blocks

Nitrogen Compounds

Organic Building Blocks

Polyamines