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PDZ1 DOMAIN INHIBITOR PEPTIDE

Product Name
PDZ1 DOMAIN INHIBITOR PEPTIDE
CAS No.
1315378-73-4
Chemical Name
PDZ1 DOMAIN INHIBITOR PEPTIDE
Synonyms
PDZ1 DOMAIN INHIBITOR PEPTIDE;Tyr-Lys-cyclo(Lys-Thr-Glu-β-Ala)-Val;L-Valine, L-tyrosyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-alanyl-, (5→3)-lactam
CBNumber
CB0239060
Molecular Formula
C38H61N9O11
Formula Weight
819.96
MOL File
1315378-73-4.mol
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PDZ1 DOMAIN INHIBITOR PEPTIDE Property

Boiling point:
1304.2±65.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
solubility 
Soluble to 1 mg/ml in 5% acetonitrile / Water and to 4 mg/ml in DMSO
pka
3.36±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
Tyr-Lys-Lys-Thr-Glu-Ala-Val (Lactam bridge:Lys3-Glu5)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2207
Product name
PDZ1Domaininhibitorpeptide
Packaging
1
Price
$168
Updated
2021/12/16
ApexBio Technology
Product number
B5271
Product name
PDZ1Domaininhibitorpeptide
Packaging
1mg
Price
$377
Updated
2021/12/16
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PDZ1 DOMAIN INHIBITOR PEPTIDE Chemical Properties,Usage,Production

Uses

PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain[1].

References

[1] Andrea Piserchio, et al. Targeting specific PDZ domains of PSD-95; structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Chem Biol. 2004 Apr;11(4):469-73. DOI:10.1016/j.chembiol.2004.03.013

PDZ1 DOMAIN INHIBITOR PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PDZ1 DOMAIN INHIBITOR PEPTIDE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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Creative Peptides
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BOC Sciences
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