D-Trp(34) neuropeptide Y
- Product Name
- D-Trp(34) neuropeptide Y
- CAS No.
- 153549-84-9
- Chemical Name
- D-Trp(34) neuropeptide Y
- Synonyms
- D-Trp(34) neuropeptide Y;Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-D-Trp-Arg-Tyr-NH2
- CBNumber
- CB91340911
- Molecular Formula
- C196H289N55O56
- Formula Weight
- 4311.72676
- MOL File
- 153549-84-9.mol
D-Trp(34) neuropeptide Y Property
- storage temp.
- Store at -20°C
- solubility
- Soluble to 0.20 mg/ml in 20% acetonitrile
- form
- Powder
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 3436
- Product name
- [D-Trp34] Neuropeptide Y
- Packaging
- 200U
- Price
- $339
- Updated
- 2021/12/16
- Product number
- B7408
- Product name
- [D-Trp34] Neuropeptide Y
- Packaging
- 200ug
- Price
- $534
- Updated
- 2021/12/16
- Product number
- orb364077
- Product name
- [D-Trp34]-Neuropeptide Y
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $708.9
- Updated
- 2021/12/16
- Product number
- orb364077
- Product name
- [D-Trp34]-Neuropeptide Y
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $1756.1
- Updated
- 2021/12/16
- Product number
- orb364077
- Product name
- [D-Trp34]-Neuropeptide Y
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $2624.8
- Updated
- 2021/12/16
D-Trp(34) neuropeptide Y Chemical Properties,Usage,Production
Uses
[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats[1][2].
in vivo
[D-Trp34]-Neuropeptide Y (0, 8 and 16 μg/rat; I.C.V) stimulats food intake to the same extent in both lean and obese rats 1 h after injection at a dose of 16 μg in male Zucker rats[2].
IC 50
NPY Y5 receptor
References
[1] E M Parker, et al. [D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake. Peptides. 2000 Mar;21(3):393-9. DOI:10.1016/s0196-9781(00)00156-x
[2] Bernard Beck, et al. Responsiveness of obese Zucker rats to [D-Trp34]-NPY supports the targeting of Y5 receptor for obesity treatment. Nutr Neurosci. Oct-Dec 2007;10(5-6):211-4. DOI:10.1080/10284150701676222
D-Trp(34) neuropeptide Y Preparation Products And Raw materials
Raw materials
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