ChemicalBook > CAS DataBase List > D-Trp(34) neuropeptide Y

D-Trp(34) neuropeptide Y

Product Name
D-Trp(34) neuropeptide Y
CAS No.
153549-84-9
Chemical Name
D-Trp(34) neuropeptide Y
Synonyms
D-Trp(34) neuropeptide Y;Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-D-Trp-Arg-Tyr-NH2
CBNumber
CB91340911
Molecular Formula
C196H289N55O56
Formula Weight
4311.72676
MOL File
153549-84-9.mol
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D-Trp(34) neuropeptide Y Property

storage temp. 
Store at -20°C
solubility 
Soluble to 0.20 mg/ml in 20% acetonitrile
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
3436
Product name
[D-Trp34] Neuropeptide Y
Packaging
200U
Price
$339
Updated
2021/12/16
ApexBio Technology
Product number
B7408
Product name
[D-Trp34] Neuropeptide Y
Packaging
200ug
Price
$534
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364077
Product name
[D-Trp34]-Neuropeptide Y
Purity
> 95%
Packaging
1mg
Price
$708.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364077
Product name
[D-Trp34]-Neuropeptide Y
Purity
> 95%
Packaging
5mg
Price
$1756.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364077
Product name
[D-Trp34]-Neuropeptide Y
Purity
> 95%
Packaging
10mg
Price
$2624.8
Updated
2021/12/16
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D-Trp(34) neuropeptide Y Chemical Properties,Usage,Production

Uses

[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats[1][2].

in vivo

[D-Trp34]-Neuropeptide Y (0, 8 and 16 μg/rat; I.C.V) stimulats food intake to the same extent in both lean and obese rats 1 h after injection at a dose of 16 μg in male Zucker rats[2].

IC 50

NPY Y5 receptor

References

[1] E M Parker, et al. [D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake. Peptides. 2000 Mar;21(3):393-9. DOI:10.1016/s0196-9781(00)00156-x
[2] Bernard Beck, et al. Responsiveness of obese Zucker rats to [D-Trp34]-NPY supports the targeting of Y5 receptor for obesity treatment. Nutr Neurosci. Oct-Dec 2007;10(5-6):211-4. DOI:10.1080/10284150701676222

D-Trp(34) neuropeptide Y Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Trp(34) neuropeptide Y Suppliers

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