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Pamoic acid disodium salt

Product Name
Pamoic acid disodium salt
CAS No.
6640-22-8
Chemical Name
Pamoic acid disodium salt
Synonyms
PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
CBNumber
CB0247382
Molecular Formula
C23H17NaO6
Formula Weight
412.37
MOL File
6640-22-8.mol
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Pamoic acid disodium salt Property

Melting point:
300 °C
Density 
1.55[at 20℃]
vapor pressure 
0.001Pa at 25℃
storage temp. 
Desiccate at RT
solubility 
insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO
form 
solid
color 
Pale yellow
Water Solubility 
43g/L at 20℃
LogP
-3.2 at 20℃
CAS DataBase Reference
6640-22-8(CAS DataBase Reference)
EPA Substance Registry System
2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-37/38-41-48
Safety Statements 
24/25-45-36/37/39-26-22
WGK Germany 
3
HS Code 
2918.29.7500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P5022
Product name
Pamoic acid disodium salt
Packaging
25g
Price
$101
Updated
2024/03/01
TCI Chemical
Product number
P1059
Product name
Pamoic Acid Disodium Salt Monohydrate
Purity
>98.0%(HPLC)
Packaging
25g
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
P1059
Product name
Pamoic Acid Disodium Salt Monohydrate
Purity
>98.0%(HPLC)
Packaging
250g
Price
$295
Updated
2024/03/01
Tocris
Product number
4298
Product name
Pamoic acid disodium salt
Purity
≥99%(HPLC)
Packaging
50
Price
$101
Updated
2021/12/16
TRC
Product number
P173503
Product name
Pamoic acid disodium salt
Packaging
50mg
Price
$100
Updated
2021/12/16
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Pamoic acid disodium salt Chemical Properties,Usage,Production

Chemical Properties

pale yellow to yellow powder

Uses

Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.

Flammability and Explosibility

Not classified

Biological Activity

Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.

Pamoic acid disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Pamoic acid disodium salt Suppliers

Americas 1 Belgium 1 CHINA 101 Europe 3 Germany 3 India 10 Japan 3 South Korea 1 Switzerland 2 United Kingdom 11 United States 30 USA 1 Global 167
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from Pamoic acid disodium salt manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Pamoic Acid Disodium Salt Monohydrate 6640-22-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

6640-22-8, Pamoic acid disodium saltRelated Search:

Sodium Phosphate, Dibasic Sodium phosphate dibasic dodecahydrate Pamoic acid 1,1'-METHYLENEDI-2-NAPHTHOL 2,2'-METHYLENEDIPHENOL 2-Naphthoic acid Sodium diacetate 2-Naphthalenemethanol 3-Hydroxy-2-naphthoic acid Sodium salicylate 3-Methylsalicylic acid 1,3-DIMETHYLNAPHTHALENE Pamoic acid disodium salt 2-HYDROXY-3-NAPHTHOIC ACID SODIUM SALT EMBONIC ACID 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT 3,3'-DICARBOXYDIPHENYLMETHANE 3-METHYLSALICYLIC ACID SODIUM SALT

  • PAMOIC ACID DISODIUM SALT 98+%
  • DisodiumPamoate98%
  • DISODIUMEMBONATE
  • 4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate
  • 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt
  • Disodium 4-[(3-carboxylato-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate
  • 1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid sodium) salt
  • 1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid)disodium salt
  • Embonic Acid Disodium Salt 4,4'-Methylenebis(3-hydroxy-2-naphthoic Acid Sodium Salt)
  • PaMoic Acid DisodiuM Salt&nbsp
  • 2-Naphthalenecarboxylicacid, 4,4'-Methylenebis[3-hydroxy-, sodiuM salt (1:2)
  • Pamoic acid disodium salt hydrate
  • Sodium 4,4'-methylenebis(3-hydroxy-2-naphthoate)
  • EMBONIC ACID DISODIUM SALT
  • PAMOIC ACID DISODIUM SALT
  • PAMOIC ACID NA
  • sodium pamoate
  • 4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID) DISODIUM SALT
  • 4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID SODIUM SALT)
  • 2,2'-DIHYDROXY-1,1'-DINAPHTHYLMETHANE-3,3'-DICARBOXYLIC ACID DISODIUM SALT
  • 1,1'-METHYLENE-BIS[2-HYDROXY-3-NAPHTHOIC ACID] DISODIUM SALT
  • disodium 4,4'-methylenebis[3-hydroxy-2-naphthoate]
  • PAMOIC ACID DISODIUM
  • PAMOIC ACID DISODIUM SALT 98%
  • 4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) disodium salt
  • PamoicAcidDisodiumSaltMonohydrate&gt
  • isodium,3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate
  • Cyprofuram Impurity 1
  • Sodium 4,4'-methylenebis(3-hydroxy-2-naphthoate)
  • 6640-22-8
  • C23H14Na2O6
  • C23H14O6Na2
  • C23H16O62Na
  • C23H14Na2O6H2O
  • C23H16O6Na
  • C23H16Na2O6
  • C23H14O62Na