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Pamoic acid disodium salt

Product Name
Pamoic acid disodium salt
CAS No.
6640-22-8
Chemical Name
Pamoic acid disodium salt
Synonyms
PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
CBNumber
CB0247382
Molecular Formula
C23H17NaO6
Formula Weight
412.37
MOL File
6640-22-8.mol
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Pamoic acid disodium salt Property

Melting point:
300 °C
Density 
1.55[at 20℃]
vapor pressure 
0.001Pa at 25℃
storage temp. 
Desiccate at RT
solubility 
insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO
form 
solid
color 
Pale yellow
Water Solubility 
43g/L at 20℃
LogP
-3.2 at 20℃
CAS DataBase Reference
6640-22-8(CAS DataBase Reference)
EPA Substance Registry System
2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-37/38-41-48
Safety Statements 
24/25-45-36/37/39-26-22
WGK Germany 
3
HS Code 
2918.29.7500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P5022
Product name
Pamoic acid disodium salt
Packaging
25g
Price
$101
Updated
2024/03/01
TCI Chemical
Product number
P1059
Product name
Pamoic Acid Disodium Salt Monohydrate
Purity
>98.0%(HPLC)
Packaging
25g
Price
$61
Updated
2024/03/01
TCI Chemical
Product number
P1059
Product name
Pamoic Acid Disodium Salt Monohydrate
Purity
>98.0%(HPLC)
Packaging
250g
Price
$295
Updated
2024/03/01
Tocris
Product number
4298
Product name
Pamoic acid disodium salt
Purity
≥99%(HPLC)
Packaging
50
Price
$101
Updated
2021/12/16
TRC
Product number
P173503
Product name
Pamoic acid disodium salt
Packaging
50mg
Price
$100
Updated
2021/12/16
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Pamoic acid disodium salt Chemical Properties,Usage,Production

Chemical Properties

pale yellow to yellow powder

Uses

Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.

Flammability and Explosibility

Not classified

Biological Activity

Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.

Pamoic acid disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Pamoic acid disodium salt Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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86-21-61259102
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market03@meryer.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com
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Energy Chemical
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Shandong Xiya Chemical Co., Ltd
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0539-6365991
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3007715519@qq.com
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Maya High Purity Chemicals
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+86 (573) 82222445 (0)18006601000 452520369
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+86 (573) 82222643
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sales@maya-r.com
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Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
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+86-571-82880190
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Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
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021-57711696
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marketing_china@spectrumchemical.com
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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03-36680489
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03-3668-0520
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Sales-JP@TCIchemicals.com
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Japan
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View Lastest Price from Pamoic acid disodium salt manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Pamoic Acid Disodium Salt Monohydrate 6640-22-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

6640-22-8, Pamoic acid disodium saltRelated Search:


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