ChemicalBook > CAS DataBase List > Pamoic acid disodium salt

Pamoic acid disodium salt

Product Name: Pamoic acid disodium salt
CAS No.: 6640-22-8
Chemical Name: Pamoic acid disodium salt
Synonyms: PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
CBNumber: CB0247382
Molecular Formula: C23H17NaO6
Formula Weight: 412.37
MOL File: 6640-22-8.mol

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Pamoic acid disodium salt Property

Melting point:: 300 °C
Density: 1.55[at 20℃]
vapor pressure: 0.001Pa at 25℃
storage temp.: Desiccate at RT
solubility: insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO
form: solid
color: Pale yellow
Water Solubility: 43g/L at 20℃
LogP: -3.2 at 20℃
CAS DataBase Reference: 6640-22-8(CAS DataBase Reference)
EPA Substance Registry System: 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-37/38-41-48
Safety Statements: 24/25-45-36/37/39-26-22
WGK Germany: 3
HS Code: 2918.29.7500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P5022
Product name: Pamoic acid disodium salt
Packaging: 25g
Price: $107
Updated: 2025/07/31

TCI Chemical

Product number: P1059
Product name: Pamoic Acid Disodium Salt Monohydrate
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $61
Updated: 2025/07/31

TCI Chemical

Product number: P1059
Product name: Pamoic Acid Disodium Salt Monohydrate
Purity: >98.0%(HPLC)
Packaging: 250g
Price: $295
Updated: 2025/07/31

Tocris

Product number: 4298
Product name: Pamoic acid disodium salt
Purity: ≥99%(HPLC)
Packaging: 50
Price: $101
Updated: 2021/12/16

TRC

Product number: P173503
Product name: Pamoic acid disodium salt
Packaging: 50mg
Price: $100
Updated: 2021/12/16

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Pamoic acid disodium salt Chemical Properties,Usage,Production

Chemical Properties

pale yellow to yellow powder

Uses

Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.

Flammability and Explosibility

Not classified

Biological Activity

Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.

in vivo

Pamoic acid disodium (0-100 mg/kg; s.c.; once) induces a dose-related antinociception in the abdominal constriction test^[1].

Animal Model:	Swiss-Webster mice (30–35 g)^[1]
Dosage:	25, 50, and 100 mg/kg
Administration:	Subcutaneous injection, once
Result:	Elicited dose-related antinociception, the dose causing 50% antinociception being 40.5 mg/kg.

Pamoic acid disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pamoic acid disodium salt manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4,4"-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pamoic Acid Disodium Salt Monohydrate 6640-22-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt 6640-22-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

6640-22-8, Pamoic acid disodium saltRelated Search:

Sodium Phosphate, Dibasic Sodium phosphate dibasic dodecahydrate Pamoic acid 1,1'-METHYLENEDI-2-NAPHTHOL 2,2'-METHYLENEDIPHENOL 2-Naphthoic acid Sodium diacetate 2-Naphthalenemethanol 3-Hydroxy-2-naphthoic acid Sodium salicylate 3-Methylsalicylic acid 1,3-DIMETHYLNAPHTHALENE Pamoic acid disodium salt 2-HYDROXY-3-NAPHTHOIC ACID SODIUM SALT EMBONIC ACID 2-NAPHTHALENECARBOXYLIC ACID SODIUM SALT 3,3'-DICARBOXYDIPHENYLMETHANE 3-METHYLSALICYLIC ACID SODIUM SALT

PAMOIC ACID DISODIUM SALT 98+%

DisodiumPamoate98%

DISODIUMEMBONATE

4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate

2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt

Disodium 4-[(3-carboxylato-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate

1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid sodium) salt

1,1'-Methylenebis(2-hydroxy-3-naphthalenecarboxylic acid)disodium salt

Embonic Acid Disodium Salt 4,4'-Methylenebis(3-hydroxy-2-naphthoic Acid Sodium Salt)

PaMoic Acid DisodiuM Salt&nbsp

2-Naphthalenecarboxylicacid, 4,4'-Methylenebis[3-hydroxy-, sodiuM salt (1:2)

Pamoic acid disodium salt hydrate

Sodium 4,4'-methylenebis(3-hydroxy-2-naphthoate)

EMBONIC ACID DISODIUM SALT

PAMOIC ACID DISODIUM SALT

PAMOIC ACID NA

sodium pamoate

4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID SODIUM SALT)

2,2'-DIHYDROXY-1,1'-DINAPHTHYLMETHANE-3,3'-DICARBOXYLIC ACID DISODIUM SALT

1,1'-METHYLENE-BIS[2-HYDROXY-3-NAPHTHOIC ACID] DISODIUM SALT

disodium 4,4'-methylenebis[3-hydroxy-2-naphthoate]

PAMOIC ACID DISODIUM

PAMOIC ACID DISODIUM SALT 98%

4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) disodium salt

PamoicAcidDisodiumSaltMonohydrate&gt

isodium,3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate

4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt

3-carboxy-1-[(3-carboxy-2-oxidonaphthalen-1-yl)methyl]naphthalen-2-olate

Cyprofuram Impurity 1

Disodium 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate)

4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) disodium salt

6640-22-8

C23H14Na2O6

C23H14O6Na2

C23H16O62Na

C23H14Na2O6H2O

C23H16O6Na

C23H16Na2O6

C23H14O62Na