CCT129202
- Product Name
- CCT129202
- CAS No.
- 942947-93-5
- Chemical Name
- CCT129202
- Synonyms
- CS-407;CCT129202;CCT129202 USP/EP/BP;CCT129202 (CCT-129202;2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-1H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(th;1-Piperazineacetamide, 4-[6-chloro-2-[4-(dimethylamino)phenyl]-3H-imidazo[4,5-b]pyridin-7-yl]-N-2-thiazolyl-;2-[4-[6-Chloro-2-(4-dimethylaminophenyl)-3H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]-N-(thiazol-2-yl)acetamide
- CBNumber
- CB02561464
- Molecular Formula
- C23H25ClN8OS
- Formula Weight
- 497.02
- MOL File
- 942947-93-5.mol
CCT129202 Property
- Density
- 1.427
- storage temp.
- Store at -20°C
- solubility
- DMSO : 1 mg/mL (2.01 mM; Need ultrasonic)
- form
- Powder
- pka
- 9.26±0.50(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 29053
- Product name
- CCT129202
- Packaging
- 1mg
- Price
- $50
- Updated
- 2024/03/01
- Product number
- 29053
- Product name
- CCT129202
- Packaging
- 10mg
- Price
- $365
- Updated
- 2024/03/01
- Product number
- 29053
- Product name
- CCT129202
- Packaging
- 5mg
- Price
- $195
- Updated
- 2024/03/01
- Product number
- CS-0206
- Product name
- CCT129202
- Purity
- 98.24%
- Packaging
- 100mg
- Price
- $935
- Updated
- 2021/12/16
- Product number
- KIN0000931
- Product name
- CCT-129202
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $1127.86
- Updated
- 2021/12/16
CCT129202 Chemical Properties,Usage,Production
Biological Activity
CCT129202 is an ATP-competitive pan-Aurora inhibitor with IC50s of 0.042 μM, 0.198 μM and 0.227 μM for Aurora A, Aurora B and Aurora C, respectively, and has a weaker effect on FGFR3, GSK3β, PDGFRβ, etc.
in vivo
CCT129202 at a dose of 100 mg/kg subcutaneously injected HCT116 colon xenografts in athymic mice, after 30 minutes, caused a ~50% decrease in histone H3 phosphorylation, and after 9 days of treatment, significantly inhibited tumor growth, compared with the control group , inhibited by 57.7%.
target
Aurora A
CCT129202 Preparation Products And Raw materials
Raw materials
Preparation Products
CCT129202 Suppliers
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- 02118516225986 18516225986
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- China
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- +86 (531) 88811783
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- +86 (531) 55696010 QQ 1762738062
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- Country
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View Lastest Price from CCT129202 manufacturers
- Product
- CCT129202 942947-93-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08