Y 11

Product Name: Y 11
CAS No.: 1086639-59-9
Chemical Name: Y 11
Synonyms: Y 11;NSC206142;1-(2-Hydroxyethyl)-3,5,7-triaza-1-azaniatricyclo[3.3.1.13,7]decane bromide;1-(2-Hydroxyethyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane BroMide;3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(2-hydroxyethyl)-, broMide
CBNumber: CB02603010
Molecular Formula: C8H17BrN4O
Formula Weight: 265.15078
MOL File: 1086639-59-9.mol

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Y 11 Property

storage temp.: -20°C
solubility: H2O: soluble25mg/mL, clear
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 36/37/39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0968
Product name: Y11
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $94.6
Updated: 2022/05/15

Cayman Chemical

Product number: 18521
Product name: Y11
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18521
Product name: Y11
Purity: ≥95%
Packaging: 5mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 18521
Product name: Y11
Purity: ≥95%
Packaging: 10mg
Price: $151
Updated: 2024/03/01

Cayman Chemical

Product number: 18521
Product name: Y11
Purity: ≥95%
Packaging: 25mg
Price: $321
Updated: 2024/03/01

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Y 11 Chemical Properties,Usage,Production

Uses

Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397. At 100 μM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.[Cayman Chemical]

Uses

Y 11 is a potent inhibitor of focal adhesion kinase (FAK); Y 11 prevents FAK autophosphorylation at the Y397 site (IC50 ~ 50 nM in an in vitro kinase assay). Displays selectivity for FAK over a panel of other kinases (concentration used in assay = 1 μM). Y 11 decreases cell viability in a number of cancer cell lines; blocks colony formation in SW620 and BT474 cell lines.

Y 11 Preparation Products And Raw materials

Raw materials

Preparation Products

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Y 11 Suppliers

China 42 India 1 United Kingdom 2 United States 6 Global 51

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

ApexBio Technology

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Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

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Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

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Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Riedel-de Haen AG

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Country: United States
ProdList: 6773
Advantage: 87

1086639-59-9, Y 11Related Search:

Y16 1,2,4,5-BENZENETETRAMINE TETRAHYDROCHLORIDE

Y 11

3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(2-hydroxyethyl)-, broMide

1-(2-Hydroxyethyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane BroMide

NSC206142

1-(2-Hydroxyethyl)-3,5,7-triaza-1-azaniatricyclo[3.3.1.13,7]decane bromide

1086639-59-9

C8H17N4OBr