ChemicalBook > CAS DataBase List > Mutant IDH1 inhibitor

Mutant IDH1 inhibitor

Product Name
Mutant IDH1 inhibitor
CAS No.
1429180-08-4
Chemical Name
Mutant IDH1 inhibitor
Synonyms
SCHEMBL14831541;Mutant IDH1 inhibitor;Mutant IDH1 inhibitor,Mutant IDH-1 inhibitor,inhibit,Isocitrate Dehydrogenase (IDH),Inhibitor;(S)-3-(2-(((S)-1-(4-((4-Acetylpiperazin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one;(4S)-3-[2-[[(1S)-1-[4-[(4-Acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-2-oxazolidinone;2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4-acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
CBNumber
CB02682017
Molecular Formula
C25H34N6O3
Formula Weight
466.58
MOL File
1429180-08-4.mol
More
Less

Mutant IDH1 inhibitor Property

storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 34 mg/mL (72.87 mM)
form 
Powder
color 
White to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
5mg
Price
$205
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
50mg
Price
$1050
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
100mg
Price
$1800
Updated
2021/12/16
Crysdot
Product number
CD31003521
Product name
MutantIDH1inhibitor
Purity
98+%
Packaging
10mg
Price
$445
Updated
2021/12/16
More
Less

Mutant IDH1 inhibitor Chemical Properties,Usage,Production

Description

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.

in vitro

In Vitro:Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].

References

References:[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404

Mutant IDH1 inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Mutant IDH1 inhibitor Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Beckham Medical Technology Co., Ltd
Tel
021-13816613772 13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
442
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58

1429180-08-4, Mutant IDH1 inhibitorRelated Search:


  • Mutant IDH1 inhibitor
  • (4S)-3-[2-[[(1S)-1-[4-[(4-Acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-2-oxazolidinone
  • SCHEMBL14831541
  • 2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4-acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
  • Mutant IDH1 inhibitor,Mutant IDH-1 inhibitor,inhibit,Isocitrate Dehydrogenase (IDH),Inhibitor
  • (S)-3-(2-(((S)-1-(4-((4-Acetylpiperazin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one
  • 1429180-08-4