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Mutant IDH1 inhibitor

Product Name
Mutant IDH1 inhibitor
CAS No.
1429180-08-4
Chemical Name
Mutant IDH1 inhibitor
Synonyms
SCHEMBL14831541;Mutant IDH1 inhibitor;Mutant IDH1 inhibitor,Mutant IDH-1 inhibitor,inhibit,Isocitrate Dehydrogenase (IDH),Inhibitor;(S)-3-(2-(((S)-1-(4-((4-Acetylpiperazin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one;(4S)-3-[2-[[(1S)-1-[4-[(4-Acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-2-oxazolidinone;2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4-acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
CBNumber
CB02682017
Molecular Formula
C25H34N6O3
Formula Weight
466.58
MOL File
1429180-08-4.mol
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Mutant IDH1 inhibitor Property

storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 34 mg/mL (72.87 mM)
form 
Powder
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
5mg
Price
$205
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
50mg
Price
$1050
Updated
2021/12/16
ChemScene
Product number
CS-2102
Product name
MutantIDH1inhibitor
Purity
98.69%
Packaging
100mg
Price
$1800
Updated
2021/12/16
Crysdot
Product number
CD31003521
Product name
MutantIDH1inhibitor
Purity
98+%
Packaging
10mg
Price
$445
Updated
2021/12/16
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Mutant IDH1 inhibitor Chemical Properties,Usage,Production

Description

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.

in vitro

In Vitro:Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].

References

References:[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404

Mutant IDH1 inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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Mutant IDH1 inhibitor Suppliers

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1429180-08-4, Mutant IDH1 inhibitorRelated Search:


  • Mutant IDH1 inhibitor
  • (4S)-3-[2-[[(1S)-1-[4-[(4-Acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-2-oxazolidinone
  • SCHEMBL14831541
  • 2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4-acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
  • Mutant IDH1 inhibitor,Mutant IDH-1 inhibitor,inhibit,Isocitrate Dehydrogenase (IDH),Inhibitor
  • (S)-3-(2-(((S)-1-(4-((4-Acetylpiperazin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one
  • 1429180-08-4