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SCIADOPITYSIN

Product Name
SCIADOPITYSIN
CAS No.
521-34-6
Chemical Name
SCIADOPITYSIN
Synonyms
Nsc 45108;SCIADOPITYSIN;Einecs 208-311-5;SCIADOPITYSIN(SH);4',4''',7-Trimethoxyamentoflavone;AMENTOFLAVONE-7,4',4'-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4''-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4'''-TRIMETHYL ETHER;Sciadopitysin, 95%, from Ginkgo biloba L.;AMENTOFLAVONE-7,4'',4''-TRIMETHYL ETHER WITH HPLC
CBNumber
CB0273404
Molecular Formula
C33H24O10
Formula Weight
580.54
MOL File
521-34-6.mol
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SCIADOPITYSIN Property

Melting point:
296-298°C
Boiling point:
839.6±65.0 °C(Predicted)
Density 
1.445±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in ethanol and methan
form 
powder
pka
6.16±0.40(Predicted)
color 
Light yellow
LogP
5.500 (est)
CAS DataBase Reference
521-34-6
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Safety

Safety Statements 
24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27900
Product name
Sciadopitysin
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27900
Product name
Sciadopitysin
Packaging
50mg
Price
$841
Updated
2024/03/01
Cayman Chemical
Product number
27900
Product name
Sciadopitysin
Packaging
10mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
27900
Product name
Sciadopitysin
Packaging
25mg
Price
$513
Updated
2024/03/01
Usbiological
Product number
300938
Product name
Sciadopitysin
Packaging
20mg
Price
$462
Updated
2021/12/16
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SCIADOPITYSIN Chemical Properties,Usage,Production

Description

Sciadopitysin is a biflavonoid originally isolated from G. biloba and has diverse biological activities. It reduces cytotoxicity induced by amyloid-β (1-42) (Aβ42; ) in PC12 cells (EC50 = 9.84 μM). Sciadopitysin (0.1-10 μM) decreases methylglyoxal-induced insulin secretion, production of reactive oxygen species (ROS), cardiolipin peroxidation, and cytotoxicity in RIN-m5F pancreatic β-cells. It inhibits P-glycoprotein (P-gp; IC50 = 53.42 μM) and increases cellular toxicity of paraquat and paclitaxel in MDR1-MDCKII cells. Sciadopitysin inhibits RANKL-induced mRNA expression of the osteoclast-specific genes CTSK, TRAP, and MMP-9, activation of NF-κB, and osteoclastogenesis in a mouse model of LPS-induced bone loss.

Definition

ChEBI: A biflavonoid that is a 7, 4', 4'''-trimethyl ether derivative of amentoflavone.

target

ROS | MMP(e.g.TIMP) | NO | TNF-α | ATPase | cAMP | Beta Amyloid

SCIADOPITYSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SCIADOPITYSIN Suppliers

China 120 France 1 Germany 2 Japan 1 United Kingdom 6 United States 12 USA 1 Global 143
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View Lastest Price from SCIADOPITYSIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Sciadopitysin 521-34-6
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-19
Career Henan Chemical Co
Product
SCIADOPITYSIN 521-34-6
Price
US $350.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
10000kg
Release date
2018-07-27

521-34-6, SCIADOPITYSINRelated Search:

4-Phenylphenol 3-Biphenylmethanol SCIADOPITYSIN 2-METHOXYBIPHENYL 3,3'-Dimethylbiphenyl 4-METHOXY-3-METHYLBENZYL ALCOHOL 4'-Hydroxy-3'-methylacetophenone 2-Phenylphenol 1-(2-Hydroxy-5-methylphenyl)ethanone 2,4-Dihydroxy-3-methylbenzaldehyde 2,4,6-TRIHYDROXY-1,3-DIMETHYL BENZENE 2,2'-DIMETHOXYBIPHENYL 4',7-DIMETHOXY-5-HYDROXYFLAVONE 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E) BILOBETIN 3-Phenylbenzaldehyde 4,6-DIMETHOXYSALICYLALDEHYDE 2',4'-DIHYDROXY-3'-METHYLACETOPHENONE

  • AMENTOFLAVONE-7,4',4'''-TRIMETHYL ETHER
  • AMENTOFLAVONE-7,4',4''-TRIMETHYL ETHER
  • AMENTOFLAVONE-7,4',4'-TRIMETHYL ETHER
  • SCIADOPITYSIN
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-4-benzopyrone
  • SCIADOPITYSIN(SH)
  • AMENTOFLAVONE-7,4'',4''-TRIMETHYL ETHER WITH HPLC
  • 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-methoxy-5-(4-oxo-5-hydroxy-7-methoxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one
  • 2-(4-Methoxyphenyl)-8-[6-methoxy-3-(4-oxo-5-hydroxy-7-methoxy-4H-1-benzopyran-2-yl)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
  • 4',4''',7-Trimethoxyamentoflavone
  • 5,5'',7''-Trihydroxy-4',4''',7-trimethoxy-3',8''-biflavone
  • 5,7-Dihydroxy-8-[2-methoxy-5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
  • 5,7-Dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-methoxyphenyl)-4-benzopyrone
  • Einecs 208-311-5
  • Nsc 45108
  • 4H-1-Benzopyran-4-one,5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)-
  • 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one
  • Sciadopitysin, 95%, from Ginkgo biloba L.
  • 521-34-6
  • C33H24O10
  • Tri-substituted Flavones