2-Chlorocinnamic acid

ChemicalBook > CAS DataBase List > 2-Chlorocinnamic acid

2-Chlorocinnamic acid

Product Name: 2-Chlorocinnamic acid
CAS No.: 3752-25-8
Chemical Name: 2-Chlorocinnamic acid
Synonyms: AKOS BBB/195;AKOS B004073;AKOS BBS-00006452;Chlorocinnamicacid;RARECHEM BK HC T319;2-Chlorocinnamicaci;o-chloro-cinnamicaci;2-CLOROCINNAMIC ACID;O-CHLOROCINNAMIC ACID;OTAVA-BB BB0125160239
CBNumber: CB0278409
Molecular Formula: C9H7ClO2
Formula Weight: 182.6
MOL File: 3752-25-8.mol

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2-Chlorocinnamic acid Property

Melting point:: 208-210 °C(lit.)
Boiling point:: 260.71°C (rough estimate)
Density: 1.2377 (rough estimate)
refractive index: 1.5426 (estimate)
storage temp.: Room temperature.
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Water Solubility: Insoluble in water
form: powder to crystal
pka: 4.23(at 25℃)
color: White to Almost white
BRN: 1365198
InChIKey: KJRRTHHNKJBVBO-AATRIKPKSA-N
CAS DataBase Reference: 3752-25-8(CAS DataBase Reference)
NIST Chemistry Reference: 2-Chlorocinnamic acid(3752-25-8)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 36-26-36/37
WGK Germany: 3
RTECS: GD8450000
Hazard Note: Irritant
HS Code: 29124990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C0974
Product name: 2-Chlorocinnamic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $36
Updated: 2024/03/01

Alfa Aesar

Product number: L01606
Product name: 2-Chlorocinnamic acid, predominantly trans, 99%
Packaging: 25g
Price: $38.3
Updated: 2021/12/16

Alfa Aesar

Product number: L01606
Product name: 2-Chlorocinnamic acid, predominantly trans, 99%
Packaging: 100g
Price: $100
Updated: 2021/12/16

TRC

Product number: C428250
Product name: (E)-3-(2-Chlorophenyl)acrylicacid
Packaging: 2.5g
Price: $65
Updated: 2021/12/16

TRC

Product number: C428250
Product name: (E)-3-(2-Chlorophenyl)acrylicacid
Packaging: 500mg
Price: $45
Updated: 2021/12/16

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2-Chlorocinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder. Insoluble in water, soluble in ethanol, ethyl acetate and other organic solvents.

Uses

2-Chlorocinnamic acid is a kind of trans-cinnamate. It is used in organic synthesis.

Biological Functions

2-Chlorocinnamic acid is a cinnamic acid derivative that inhibits the hydroxylation of phenylpropanoids. It has been shown to inhibit the activity of cinnamic acid derivatives and their hydroxylation in cell lines, which is linked to the inhibition of cellulose acetate synthesis. 2-Chlorocinnamic acid also has an inhibitory effect on the chloride ion and water molecule. The chloride ion may be needed for the formation of hydrochloric acid, which is necessary for cellulose acetate hydrolysis, while water molecules are involved in many biochemical reactions. 2-Chlorocinnamic acid affects human cell lines at temperatures between 10°C and 37°C and at regiospecific sites. This oxidative dehalogenation reaction catalyzed by R. rubra was found to be regiospecific for 2-chlorocinnamic acid; the chloride ion was probably removed after the ring fission reaction.

Synthesis

O-chlorocinnamic acid is prepared by reacting o-phthalaldehyde with malonic acid.

2-Chlorocinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chlorocinnamic acid manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-Chlorocinnamic acid 3752-25-8
Price: US $32.00-1.10/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-22

Anhui Ruihan Technology Co., Ltd

Product: 2-Chlorocinnamic acid 3752-25-8
Price: US $30.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000t/year
Release date: 2023-09-07

Hebei Mojin Biotechnology Co., Ltd

Product: 3- (2-Chlorophenyl) Propenoic Acid 3752-25-8
Price: US $10.00/Kg/Drum
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000tons
Release date: 2021-10-19

3752-25-8, 2-Chlorocinnamic acidRelated Search:

4-(Diethylamino)salicylaldehyde Diphenolic acid Citric acid 2-Nitrocinnamic acid Ethyl cinnamate Pralmorelin alpha-Methylcinnamic acid Ethyl 4-methylcinnamate Methyl cinnamate Folic acid Glycine DL-α-Tocopherol Ethyl 2-(Chlorosulfonyl)acetate trans-Cinnamic acid 5-Chlorovaleric acid Cinnamic acid Octyl 4-methoxycinnamate Ascoric Acid

AKOS BBS-00006452

AKOS B004073

AKOS BBB/195

3-(2-CHLOROPHENYL)PROPENOIC ACID

3-(2-CHLORO-PHENYL)-ACRYLIC ACID

RARECHEM BK HC T319

OTAVA-BB BB0125160239

O-CHLOROCINNAMIC ACID

(2E)-3-(2-Chlorophenyl)-2-propenoic acid

2-Propenoic acid, 3-(2-chlorophenyl)-

3-(2-chlorophenyl)-2-propenoicaci

(2E)-3-(2-CHLOROPHENYL)ACRYLIC ACID

2-CHLOROCINNAMIC ACID

(E)-3-(2-chlorophenyl)-2-propenoate

3-(2-chlorophenyl)prop-2-enoic acid

3-(2-chlorophenyl)-2-propenoicacid

Cinnamic acid, o-chloro-

o-chloro-cinnamicaci

2-Chlorocinnamic acid, predominantly trans

Chlorocinnamicacid

2-CHLOROCINNAMIC ACID, 99%, PREDOMINANTL Y TRANS

2-CLOROCINNAMIC ACID

2-Chlorocinnamic acid, predominantly trans, 99.50%

ORTHO-CHLOROCINNAMICACID

2-CHLOROCINNAMIC ACID, 99.50%, PREDOMINANTLY TRANS

o-chlorocinnamic acid(2-

(E)-3-(2-Chlorophenyl)acrylic acid

2-Chlorocyciamic acid

3-(2-Chlorophenyl)acrylic acid, 3-(2-Chlorophenyl)prop-2-enoic acid

2-ChlorocycinnaMic acid

2-Chlorocinnamic Acid &gt

2-Chlorocinnamicaci

2-Chlorocinnamic acid USP/EP/BP

2-Chloro cinnamic acid,o-chloro-cinnamicaci,Chlorocinnamicacid,O-CHLOROCINNAMIC ACID,2-CLOROCINNAMIC ACID,2-ChlorocinnaMic

2-Chlorocinnamic acid-99%

3752-25-8 C9H7ClO2 2-Chlorocinnamic acid

3752-25-8

C6H5CHCClCOOH

C9H5CIO2

C9H6ClO2

Organic Building Blocks

Building Blocks

Carboxylic Acids

Carbonyl Compounds

CARBOXYLIC ACID

Aromatic Cinnamic Acids, Esters and Derivatives

Cinnamic acid

Acids & Esters

Chlorine Compounds

3752-25-8