Salicyluric acid
- Product Name
- Salicyluric acid
- CAS No.
- 487-54-7
- Chemical Name
- Salicyluric acid
- Synonyms
- NSC 524135;salicylurate;SALICYLGYCINE;SALICYLGLYCINE;salicyluricaci;SALICYLURIC ACID;Salicyloylglycine;TIMTEC-BB SBB000337;NSC 524135-13C2,15N;n-salicyloyl-glycin
- CBNumber
- CB0292276
- Molecular Formula
- C9H9NO4
- Formula Weight
- 195.17
- MOL File
- 487-54-7.mol
Salicyluric acid Property
- Melting point:
- 164-169 °C
- Boiling point:
- 331.83°C (rough estimate)
- Density
- 1.3544 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- Store at 0°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Powder, Crystals or Chunks
- pka
- 3.68±0.10(Predicted)
- color
- White to light yellow
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 487-54-7(CAS DataBase Reference)
- EPA Substance Registry System
- Glycine, N-(2-hydroxybenzoyl)- (487-54-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36/37/39-27-26
- RTECS
- MR8160000
- HS Code
- 29242998
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304IF INHALED:
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362Take off contaminated clothing and wash before reuse.
P403Store in a well-ventilated place.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 49861
- Product name
- o-Hydroxyhippuric acid
- Purity
- analytical standard
- Packaging
- 50mg
- Price
- $64.2
- Updated
- 2024/03/01
- Product number
- H942885
- Product name
- 2-HydroxyHippuricAcid
- Packaging
- 5g
- Price
- $190
- Updated
- 2021/12/16
- Product number
- 279114
- Product name
- 2-Hydroxy hippuric acid
- Packaging
- 1g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- OR4276
- Product name
- N-(2-Hydroxybenzoyl)glycine
- Packaging
- 250mg
- Price
- $27
- Updated
- 2021/12/16
- Product number
- 4658-1-X2
- Product name
- [(2-Hydroxybenzoyl)amino]acetic acid
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
Salicyluric acid Chemical Properties,Usage,Production
Description
Salicyluric acid is an N-acylglycine in which the acyl group is specified as 2-hydroxybenzoyl. It has a role as a uremic toxin and a human xenobiotic metabolite. It is a N-acylglycine and a secondary carboxamide. It is functionally related to a glycine. It is a conjugate acid of a salicylurate.
Chemical Properties
Light gray crystalline powder
Uses
Metabolite of Salicylic Acid (S088125).
2-Hydroxyhippuric acid is a phenol marker. Can be associated with dietary intake or bacterial overgrowth.
Indicators of Detoxification: A conjugate of the amino acid glycine and hydroxybenzoic acid (salicylic acid). Intake of aspirin (salicylates) or the growth of salicylate-producing gastrointestinal bacteria may elevate levels. Also increased after the ingestion of the artificial sweetener aspartame (Nutrasweet).
Definition
ChEBI: An N-acylglycine in which the acyl group is specified as 2-hydroxybenzoyl.
Synthesis
The synthesis of Salicyluric acid is as follows:
To a solution of 5 g of glycine in 50ml of 10%NaOH was stirred at room temperature upon slowaddition of salicyloyl chloride, and the resultingmixture was stirred overnight. Progress of the reaction was followed by TLC (hexane : ethylacetate, 7 : 3).Then the reaction mixture was treated with crushed iceupon stirring. Concentrated HCl was added dropwiseand stirring was continued until the mixture turnedacidic. For removing the residual benzoic acid the mixture was treated with 10-12 mL of CCl4, boiled and then filtered. A pinkish white solid was obtained, yield 90%, mp 165°C.
Salicyluric acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Salicyluric acid manufacturers
- Product
- 2-HYDROXYHIPPURIC ACID 487-54-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-HYDROXYHIPPURIC ACID 487-54-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2019-12-17