ChemicalBook > CAS DataBase List > 3-METHYL-1H-INDAZOLE

3-METHYL-1H-INDAZOLE

Product Name
3-METHYL-1H-INDAZOLE
CAS No.
3176-62-3
Chemical Name
3-METHYL-1H-INDAZOLE
Synonyms
3-METHYL-1H-INDAZOLE;1H-Indazole, 3-methyl-;Benzenamine,N,N,3,9-tetramethyl-;1-Propanone,1-(3,9-dichlorophenyl)-
CBNumber
CB0303785
Molecular Formula
C8H8N2
Formula Weight
132.16
MOL File
3176-62-3.mol
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3-METHYL-1H-INDAZOLE Property

Melting point:
113°C
Boiling point:
234.08°C (rough estimate)
Density 
1.1083 (rough estimate)
refractive index 
1.6013 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
14.39±0.40(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M336748
Product name
3-Methyl-1H-indazole
Packaging
500mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
072395
Product name
3-Methyl-1H-indazole
Purity
95+%
Packaging
5g
Price
$78
Updated
2021/12/16
Matrix Scientific
Product number
072395
Product name
3-Methyl-1H-indazole
Purity
95+%
Packaging
1g
Price
$24
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-B4
Product name
3-Methyl-1H-indazole
Packaging
250mg
Price
$33
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-B4
Product name
3-Methyl-1H-indazole
Packaging
1g
Price
$100
Updated
2021/12/16
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3-METHYL-1H-INDAZOLE Chemical Properties,Usage,Production

Description

3-Methyl-1H-indazole is a heterocyclic alkyl compound containing nitrogen and three methyl groups. It is used as an intermediate in the synthesis of other compounds. It has been shown to have anti-inflammatory properties in vitro. It also inhibits neutrophil chemotaxis and may be used to treat inflammatory diseases such as trigeminal neuralgia or heart disease. 3-Methyl-1H-indazole has also been shown to inhibit histamine H3 receptor activity, which may account for its effects on eye diseases and bladder cancer.

Uses

3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli[1].

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
Synthesis, p. 982, 1984

References

[1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003.

3-METHYL-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-METHYL-1H-INDAZOLE Suppliers

Pure Chemistry Scientific Inc.
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View Lastest Price from 3-METHYL-1H-INDAZOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-METHYL-1H-INDAZOLE 3176-62-3
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-08
Career Henan Chemical Co
Product
3-METHYL-1H-INDAZOLE 3176-62-3
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19