ChemicalBook > CAS DataBase List > IDO-IN-3
IDO-IN-3
- Product Name
- IDO-IN-3
- CAS No.
- 2070018-30-1
- Chemical Name
- IDO-IN-3
- Synonyms
- IDO-IN-3;IDO inhibitor 3;IDO IN 3,IDOIN3;1,2,5-Oxadiazole-3-carboximidamide, 4-[(2-aminoethyl)amino]-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-
- CBNumber
- CB03041413
- Molecular Formula
- C11H12BrFN6O2
- Formula Weight
- 359.15
- MOL File
- 2070018-30-1.mol
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IDO-IN-3 Property
- Boiling point:
- 570.8±60.0 °C(Predicted)
- Density
- 1.86±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Ethanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 7?+-.0.69(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28432
- Product name
- IDO-IN-3
- Packaging
- 8mg
- Price
- $1207
- Updated
- 2024/03/01
AK Scientific
- Product number
- 9224EM
- Product name
- Ido-IN-3
- Packaging
- 8mg
- Price
- $1443
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-4600
- Product name
- IDO-IN-3
- Purity
- 99.88%
- Packaging
- 50mg
- Price
- $2160
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-4600
- Product name
- IDO-IN-3
- Purity
- 99.88%
- Packaging
- 2mg
- Price
- $276
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-4600
- Product name
- IDO-IN-3
- Purity
- 99.88%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
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IDO-IN-3 Chemical Properties,Usage,Production
Description
IDO-IN-3 is an inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1; IC50s = 290 and 98 nM for the human recombinant enzyme in a cell-free assay and in HeLa cells, respectively).
Uses
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
IC 50
IDO: 290 nM (IC50); IDO: 98 nM (IC50, in HeLa cell)
References
[1] Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491. DOI:10.1021/acsmedchemlett.6b00391
IDO-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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