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Cetrorelix acetate

Product Name
Cetrorelix acetate
CAS No.
120287-85-6
Chemical Name
Cetrorelix acetate
Synonyms
CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
CBNumber
CB0316370
Molecular Formula
C70H92ClN17O14
Formula Weight
1431.04
MOL File
120287-85-6.mol
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Cetrorelix acetate Property

Melting point:
>259°C (dec.)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly, Heated), Methanol (Very Slightly)
form 
Solid
pka
9.82±0.15(Predicted)
color 
White to Off-White
InChIKey
SBNPWPIBESPSIF-MHWMIDJBSA-N
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Safety

Hazardous Substances Data
120287-85-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Tocris
Product number
3536
Product name
Cetrorelix acetate
Packaging
1
Price
$224
Updated
2021/12/16
Usbiological
Product number
163043
Product name
Cetrorelix Acetate
Packaging
5mg
Price
$375
Updated
2021/12/16
Usbiological
Product number
254921
Product name
Cetrorelix Acetate
Packaging
1mg
Price
$480
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
1mg
Price
$695.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
5mg
Price
$1480.7
Updated
2021/12/16
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Cetrorelix acetate Chemical Properties,Usage,Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

brand name

Cetrotide (Serono).

Cetrorelix acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cetrorelix acetate Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Creative Peptides
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Email
info@creative-peptides.com
Country
United States
ProdList
6083
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Alfa Chemistry
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Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
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BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
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United States
ProdList
19553
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Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
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58
Protheragen-ING
Tel
+16313385890
Email
info@protheragen-ing.com
Country
United States
ProdList
3868
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Wilshire Chemical Company Inc.
Tel
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WilshrChem@AOL.COM
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United States
ProdList
3498
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58
Selleck Chemicals LLC
Tel
--
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Email
info@selleckchem.com
Country
United States
ProdList
824
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60
Focus Synthesis LLC
Tel
--
Fax
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Email
acd@focussynthesis.com
Country
United States
ProdList
2487
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Waterstone Technology, LLC
Tel
--
Fax
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Email
sales@waterstonetech.com
Country
United States
ProdList
6786
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3B Scientific Corporation
Tel
--
Fax
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Email
sales@3bsc.com
Country
United States
ProdList
6718
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47
BioWorld
Tel
--
Fax
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Email
save@bio-WORLD.com
Country
United States
ProdList
148
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AnaSpec, Inc.
Tel
--
Fax
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Email
service@anaspec.com
Country
United States
ProdList
4871
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View Lastest Price from Cetrorelix acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cetrorelix acetate 120287-85-6
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2021-10-28
Shanghai Affida new material science and technology center
Product
Cetrorelix acetate 120287-85-6
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99
Supply Ability
50000KG/month
Release date
2024-04-12
Hebei Fengjia New Material Co., Ltd
Product
Cetrorelix acetate 120287-85-6
Price
US $6.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-09-10

120287-85-6, Cetrorelix acetateRelated Search:


  • AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH
  • Cetrorelix acetate
  • CETRORELIX
  • CETRORELIX ACID
  • CETRIZINEDIHYDROCHLORIDE
  • N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2
  • Cetrorelixum
  • Cetrorelixum [inn-latin]
  • Unii-oon1hfz4ba
  • Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt
  • D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-
  • Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2
  • Cetrorelix?Acetate impurity
  • Cetrorelix acetate USP/EP/BP
  • Cetrorelix(Cetrorelix acetate)
  • Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2
  • 120287-85-6
  • 20287-85-6
  • C70H92ClN17O14
  • C70H92CIN17O14C2H4O2
  • Peptide
  • GYL