7-(TRIFLUOROMETHYL)QUINOLINE
- Product Name
- 7-(TRIFLUOROMETHYL)QUINOLINE
- CAS No.
- 325-14-4
- Chemical Name
- 7-(TRIFLUOROMETHYL)QUINOLINE
- Synonyms
- 7-Trrfluoromethylquinoline;7-(TRIFLUOROMETHYL)QUINOLINE;Quinoline, 7-(trifluoromethyl)-;7-(Trifluoromethyl)quinoline,97%
- CBNumber
- CB0347770
- Molecular Formula
- C10H6F3N
- Formula Weight
- 197.16
- MOL File
- 325-14-4.mol
7-(TRIFLUOROMETHYL)QUINOLINE Property
- Melting point:
- 65-67°C
- Boiling point:
- 236.6℃ (762 Torr)
- Density
- 1.311±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 2.55±0.14(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 325-14-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- T895680
- Product name
- 7-(Trifluoromethyl)quinoline
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3H32-3-0W
- Product name
- 7-(Trifluoromethyl)quinoline
- Purity
- 97%
- Packaging
- 10g
- Price
- $832
- Updated
- 2021/12/16
- Product number
- N530
- Product name
- 7-(Trifluoromethyl)quinoline
- Packaging
- 1g
- Price
- $215
- Updated
- 2021/12/16
- Product number
- PC520509
- Product name
- 7-(Trifluoromethyl)quinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 023763
- Product name
- 7-(Trifluoromethyl)quinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $123
- Updated
- 2021/12/16
7-(TRIFLUOROMETHYL)QUINOLINE Chemical Properties,Usage,Production
Chemical Properties
yellow powder
Synthesis
98-16-8
56-81-5
325-14-4
1. Concentrated sulfuric acid (13.7 g, 0.14 mol) was slowly added dropwise to glycerol (8.63 g, 0.094 mol) at a controlled temperature not exceeding 70 °C. 2. m-Trifluoromethylaniline (5.00 g, 0.031 mol) was added to the above mixture, and the reaction was heated up to 85 °C, and kept at 85 °C for 40 min. 3. Potassium iodide (0.30 g, 1.80 mmol), iodine (0.34 g, 1.34 mmol), and water (1.50 mL) were added in sequence, and the reaction system was heated up to 135 °C for 4 hours. 4. 1.80 mmol), iodine (0.34 g, 1.34 mmol) and water (1.50 mL) were added sequentially, and the reaction system was heated to 135 °C and the reaction was sustained for 4 h. 4. Upon completion of the reaction, it was cooled to room temperature, and the reaction mixture was quenched by pouring it into iced water and filtered through diatomaceous earth. 5. The filtrate was adjusted to a pH of 7 with ammonia, pumped, and the filtrate was extracted with ethyl acetate. 6. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure.7. The residue was purified by column chromatography to afford 7-trifluoromethylquinoline (3.50 g, 69% yield).
References
[1] Patent: CN108409649, 2018, A. Location in patent: Paragraph 0042; 0043; 0044
[2] Patent: US2010/234340, 2010, A1. Location in patent: Page/Page column 21
7-(TRIFLUOROMETHYL)QUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
7-(TRIFLUOROMETHYL)QUINOLINE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44734
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 2000
- Advantage
- 58
- Tel
- 021-57171705 13817537615
- Fax
- QQ3095748324
- sales@run-biotech.com
- Country
- China
- ProdList
- 2353
- Advantage
- 58
- Tel
- +86 0510-85629785
- Fax
- +86 0510-85625359
- Country
- China
- ProdList
- 2327
- Advantage
- 58
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
View Lastest Price from 7-(TRIFLUOROMETHYL)QUINOLINE manufacturers
- Product
- 7-(TRIFLUOROMETHYL)QUINOLINE 325-14-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 7-(TRIFLUOROMETHYL)QUINOLINE 325-14-4
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-02-04