ChemicalBook > CAS DataBase List > 2-(Cyanomethyl)benzimidazole

2-(Cyanomethyl)benzimidazole

Product Name: 2-(Cyanomethyl)benzimidazole
CAS No.: 4414-88-4
Chemical Name: 2-(Cyanomethyl)benzimidazole
Synonyms: 2-(1H-benzo[d]imidazol-2-yl)acetonitrile;1h-benzimidazole-2-acetonitrile;AKOS BC-1506;96.0%(GC&AURORA KA-5429;IFLAB-BB F0266-2601;LABOTEST-BB LT00159463;2-kyanmethylbenzimidazol;CYANOMETHYLBENZIMIDAZOLE;2-cyanomethyl-benzimidazol
CBNumber: CB0351933
Molecular Formula: C9H7N3
Formula Weight: 157.17
MOL File: 4414-88-4.mol

Less

2-(Cyanomethyl)benzimidazole Property

Melting point:: 200-205 °C (dec.)(lit.)
Boiling point:: 271.83°C (rough estimate)
Density: 1.2279 (rough estimate)
refractive index: 1.5330 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 11.01±0.10(Predicted)
color: White to Brown
Water Solubility: Insoluble in water.
BRN: 128461
InChIKey: BWOVACANEIVHST-UHFFFAOYSA-N
CAS DataBase Reference: 4414-88-4(CAS DataBase Reference)
EPA Substance Registry System: 1H-Benzimidazole-2-acetonitrile (4414-88-4)

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39-24/25
RIDADR: 3276
WGK Germany: 3
RTECS: DD5650000
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29332900
Toxicity: LD50 ivn-mus: 56 mg/kg CSLNX* NX#04148

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B5291
Product name: (2-Benzimidazolyl)acetonitrile
Purity: 97%
Packaging: 10g
Price: $97.2
Updated: 2025/07/31

TCI Chemical

Product number: B2821
Product name: (2-Benzimidazolyl)acetonitrile
Purity: >96.0%(GC)(T)
Packaging: 5g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: B2821
Product name: (2-Benzimidazolyl)acetonitrile
Purity: >96.0%(GC)(T)
Packaging: 25g
Price: $151
Updated: 2025/07/31

TRC

Product number: C990120
Product name: 2-(Cyanomethyl)benzimidazole
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C990120
Product name: 2-(Cyanomethyl)benzimidazole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Less

2-(Cyanomethyl)benzimidazole Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE FINE CRYSTALLINE POWDER

Uses

2-Benzimidazoleacetonitrile, is used as a pharmaceutical intermediate. It is also used as an intermediate in organic synthesis.

Safety Profile

Poison by intravenous route. Seealso NITRILES. When heated to decomposition it emitstoxic fumes of NOx.

Synthesis

105-56-6

95-54-5

4414-88-4

To the dry solid of o-phenylenediamine (1.08 g, 10 mmol) was added ethyl cyanoacetate (1.13 g, 10 mmol). The reaction mixture was placed in an oil bath and heated at 120 °C for 30 min, followed by cooling to room temperature. Upon completion of the reaction, the product was collected by filtration and ground with diethyl ether for purification. Finally, recrystallization was carried out from ethanol to give 2-cyanomethylbenzimidazole.

References

[1] Chemical and Pharmaceutical Bulletin, 2018, vol. 66, # 3, p. 309 - 318
[2] ChemMedChem, 2016, vol. 11, # 5, p. 539 - 548
[3] European Journal of Medicinal Chemistry, 2017, vol. 126, p. 853 - 869
[4] European Journal of Medicinal Chemistry, 2017, vol. 136, p. 270 - 282
[5] Chinese Chemical Letters, 2010, vol. 21, # 5, p. 519 - 523

2-(Cyanomethyl)benzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

COUMARIN 7 Solvent Red 196 Coumarin 30 Solvent Red 197

Less

2-(Cyanomethyl)benzimidazole Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 151 Europe 3 Germany 10 India 7 Japan 6 Russia 2 Slovakia 2 South Korea 1 Switzerland 4 Ukraine 2 United Kingdom 16 United States 51 Global 261

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
Fax: 010-60270825
Email: elainezt@sina.com
Country: China
ProdList: 1390
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Suzhou Guide Fine Material Co.Ltd.

Tel: 0512-66627360 13914021065
Fax: 0512-66627360
Email: 706938434@qq.com
Country: China
ProdList: 239
Advantage: 60

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5645
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Shanghai Dano Pharmaceutical Co., LTD(China)

Tel: 0592-6266840 15750707980
Email: sales@chemsdano.com
Country: China
ProdList: 357
Advantage: 57

Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.

Tel: 0515-89701588 13770166955
Fax: 0515-87400189
Email: orgunion@orgunion.com
Country: China
ProdList: 620
Advantage: 55

Aloespharm Co., Ltd.

Tel: 021-20960837
Fax: 021-20960837
Email: market@aloespharm.com
Country: China
ProdList: 1302
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai eliv pharmaceutical Co.,Ltd.

Tel: 021-50158063
Fax: 021-6153 1846
Email: sales@elivpharma.com
Country: China
ProdList: 477
Advantage: 58

Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.

Tel: 027-65388397 18164111589
Fax: 027-65388397
Email: 3321478047@qq.com
Country: China
ProdList: 2007
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Quzhou AMK BioTech Co., Ltd

Tel: 0570-3081766 18357083060
Fax: 0570-3072337
Email: sales@qzamkbio.com
Country: China
ProdList: 1051
Advantage: 55

Suzhou TaCheng Pharmaceutical Co., Ltd.

Tel: 0512-68253519 18260240186
Fax: 0512-68253519
Email: 122141838@qq.com
Country: China
ProdList: 76
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4740
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13856024262
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2992
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Less

View Lastest Price from 2-(Cyanomethyl)benzimidazole manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (2-Benzimidazolyl)acetonitrile 4414-88-4
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(Cyanomethyl)benzimidazole 4414-88-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(Cyanomethyl)benzimidazole 4414-88-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

4414-88-4, 2-(Cyanomethyl)benzimidazoleRelated Search:

Phenformin Acetonitrile 2-Phenylbenzimidazole-5-sulfonic acid 2-GUANIDINOBENZIMIDAZOLE 2-Phenylbenzimidazole 2-Methylbenzimidazole 5-Nitrobenzimidazole Benzimidazole 2-Chloromethylbenzimidazole (1-Methyl-1H-benzoimidazol-2-yl)acetonitrile 2-(1H-BENZIMIDAZOL-2-YL)-4-CHLORO-3-OXOBUTANENITRILE Alkyl benzimidazole benzimidazolone 2-(Cyanomethyl)benzimidazole AKOS BC-1508 BUTTPARK 125\40-73 AURORA 12449 2-(1H-BENZO[D]IMIDAZOL-2-YL)-2-(5-BROMO-2-CHLORO-6-METHYLPYRIMIDIN-4-YL)ACETONITRILE

2-Benzimidazoleacetonitrile,99%

2-Kyanmethylbenzimidazol [Czech]

2-(1H-benzimidazol-2-yl)ethanenitrile

1h-benzimidazole-2-acetonitrile

2-nitrile methylbenzimidazole

5-(CYANOMETHYL)BENZIMIDAZOLE,99%

1H-Benzimidazole-2-acetonitrile(9CI)

1H-benzimidazol-2-ylacetonitrile

(1H-Benzimidazole-2-yl)acetonitrile

2-(Cyanomethyl)-1H-benzoimidazole

2-(Cyanomethyl)benzimidazole,99%

BenziMidazole-2-acetonitrile

2-(Cyanomethyl)-1H-benzimidazole

(Benzimidazol-2-yl)acetonitrile

2-(1H-1,3-benzodiazol-2-yl)acetonitrile

2-BENZIMIDAZOLYACETONITRILE

(2-BenziMidazolyl)acetonitrile, 96.0%(GC&T

2-benzimidazolyl-acetonitril

2-cyanomethyl-benzimidazol

2-kyanmethylbenzimidazol

AURORA KA-5429

IFLAB-BB F0266-2601

LABOTEST-BB LT00159463

2-BENZIMIDAZOLE-ACETONITRILE

2-BENZIMIDAZOLYLACETONITRILE

2-(CYANOMETHYL)BENZIMIDAZOLE

(1H-BENZOIMIDAZOL-2-YL)-ACETONITRILE

1H-1,3-BENZIMIDAZOL-2-YLMETHYL CYANIDE

Benzimidazolylacetonitrile

AKOS BC-1506

(benzimidazol-2-yl)ethanenitrile

2-(1H-benzo[d]imidazol-2-yl)acetonitrile

2-CYANOMETHYLBENZIMIDAZOLE (2-BENZIMIDAZOLYLACETONITRILE)

CYANOMETHYLBENZIMIDAZOLE

(2-Benzimidazolyl)acetonitrile &gt

96.0%(GC&amp

4414-88-4

C9H7N3

Building Blocks

Benzimidazoles

Heterocyclic Building Blocks

Oxidation

Synthetic Reagents

Imidazol&Benzimidazole

Electronic Chemicals

Benzimidazoles

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

BENZIMIDAZOLE

Intermediates of Dyes and Pigments