2-(Cyanomethyl)benzimidazole

Product Name: 2-(Cyanomethyl)benzimidazole
CAS No.: 4414-88-4
Chemical Name: 2-(Cyanomethyl)benzimidazole
Synonyms: 2-(1H-benzo[d]imidazol-2-yl)acetonitrile;1h-benzimidazole-2-acetonitrile;AKOS BC-1506;96.0%(GC&AURORA KA-5429;IFLAB-BB F0266-2601;LABOTEST-BB LT00159463;2-kyanmethylbenzimidazol;CYANOMETHYLBENZIMIDAZOLE;2-cyanomethyl-benzimidazol
CBNumber: CB0351933
Molecular Formula: C9H7N3
Formula Weight: 157.17
MOL File: 4414-88-4.mol

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2-(Cyanomethyl)benzimidazole Property

Melting point:: 200-205 °C (dec.)(lit.)
Boiling point:: 271.83°C (rough estimate)
Density: 1.2279 (rough estimate)
refractive index: 1.5330 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 11.01±0.10(Predicted)
color: White to Brown
Water Solubility: Insoluble in water.
BRN: 128461
InChIKey: BWOVACANEIVHST-UHFFFAOYSA-N
CAS DataBase Reference: 4414-88-4(CAS DataBase Reference)
EPA Substance Registry System: 1H-Benzimidazole-2-acetonitrile (4414-88-4)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39-24/25
RIDADR: 3276
WGK Germany: 3
RTECS: DD5650000
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29332900
Toxicity: LD50 ivn-mus: 56 mg/kg CSLNX* NX#04148

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B5291
Product name: (2-Benzimidazolyl)acetonitrile
Purity: 97%
Packaging: 10g
Price: $97.2
Updated: 2025/07/31

TCI Chemical

Product number: B2821
Product name: (2-Benzimidazolyl)acetonitrile
Purity: >96.0%(GC)(T)
Packaging: 5g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: B2821
Product name: (2-Benzimidazolyl)acetonitrile
Purity: >96.0%(GC)(T)
Packaging: 25g
Price: $151
Updated: 2025/07/31

TRC

Product number: C990120
Product name: 2-(Cyanomethyl)benzimidazole
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C990120
Product name: 2-(Cyanomethyl)benzimidazole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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2-(Cyanomethyl)benzimidazole Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE FINE CRYSTALLINE POWDER

Uses

2-Benzimidazoleacetonitrile, is used as a pharmaceutical intermediate. It is also used as an intermediate in organic synthesis.

Safety Profile

Poison by intravenous route. Seealso NITRILES. When heated to decomposition it emitstoxic fumes of NOx.

Synthesis

105-56-6

95-54-5

4414-88-4

To the dry solid of o-phenylenediamine (1.08 g, 10 mmol) was added ethyl cyanoacetate (1.13 g, 10 mmol). The reaction mixture was placed in an oil bath and heated at 120 °C for 30 min, followed by cooling to room temperature. Upon completion of the reaction, the product was collected by filtration and ground with diethyl ether for purification. Finally, recrystallization was carried out from ethanol to give 2-cyanomethylbenzimidazole.

References

[1] Chemical and Pharmaceutical Bulletin, 2018, vol. 66, # 3, p. 309 - 318
[2] ChemMedChem, 2016, vol. 11, # 5, p. 539 - 548
[3] European Journal of Medicinal Chemistry, 2017, vol. 126, p. 853 - 869
[4] European Journal of Medicinal Chemistry, 2017, vol. 136, p. 270 - 282
[5] Chinese Chemical Letters, 2010, vol. 21, # 5, p. 519 - 523

2-(Cyanomethyl)benzimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

COUMARIN 7 Solvent Red 196 Coumarin 30 Solvent Red 197

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2-(Cyanomethyl)benzimidazole Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 151 Europe 3 Germany 10 India 7 Japan 6 Russia 2 Slovakia 2 South Korea 1 Switzerland 4 Ukraine 2 United Kingdom 16 United States 51 Global 261

Aronis

Tel: --
Fax: --
Email: aronis@aronis.ru
Country: Russia
ProdList: 6592
Advantage: 60

Chemical Block Ltd.

Tel: --
Fax: --
Email: orders@chemical-block.com
Country: Russia
ProdList: 3905
Advantage: 61

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View Lastest Price from 2-(Cyanomethyl)benzimidazole manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (2-Benzimidazolyl)acetonitrile 4414-88-4
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(Cyanomethyl)benzimidazole 4414-88-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(Cyanomethyl)benzimidazole 4414-88-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

4414-88-4, 2-(Cyanomethyl)benzimidazoleRelated Search:

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AURORA KA-5429

IFLAB-BB F0266-2601

LABOTEST-BB LT00159463

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AKOS BC-1506

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CYANOMETHYLBENZIMIDAZOLE

(2-Benzimidazolyl)acetonitrile &gt

96.0%(GC&amp

4414-88-4

C9H7N3

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