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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE

Product Name
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
CAS No.
207671-42-9
Chemical Name
PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
Synonyms
LUTIDINIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE;2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE;2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE;PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE;2,4-Pyridinedicarboxylicacid, hydrate (1:1);2,4-Pyridinedicarboxylic acid Monohydrate 98%
CBNumber
CB0356837
Molecular Formula
C7H7NO5
Formula Weight
185.13
MOL File
207671-42-9.mol
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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Property

Melting point:
246-248 °C (dec.)(lit.)
storage temp. 
Store at -20°C
solubility 
DMSO: 1.4 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form 
A crystalline solid
BRN 
131631
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P63395
Product name
2,4-Pyridinedicarboxylic acid monohydrate
Purity
98%
Packaging
5g
Price
$48.6
Updated
2024/03/01
Cayman Chemical
Product number
11138
Product name
2,4-Pyridinedicarboxylic Acid (hydrate)
Packaging
1g
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
11138
Product name
2,4-Pyridinedicarboxylic Acid (hydrate)
Packaging
5g
Price
$122
Updated
2024/03/01
TRC
Product number
P992035
Product name
2,4-Pyridinedicarboxylic acid monohydrate
Packaging
50mg
Price
$60
Updated
2021/12/16
TRC
Product number
P992035
Product name
2,4-Pyridinedicarboxylic acid monohydrate
Packaging
100mg
Price
$75
Updated
2021/12/16
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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Chemical Properties,Usage,Production

Description

2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. As a 2-OG mimic, it blocks the activity of 2-OG oxygenases, which include certain lysine demethylases and a variety of hydroxylases (e.g., prolyl, collagen, lysyl). 2,4-PDCA inhibits several Jumonji domain-containing lysine demethylases when used at low micromolar concentrations. Through its effects on hydroxylases, including prolyl hydroxlase 1 (IC50 = 1.5 μM), 2,4-PDCA modulates hypoxia-inducible factor turnover, collagen synthesis, and plant cell wall formation. It can inhibit zinc-dependent enzymes, like metallo-β-lactamase. 2,4-PDCA also affects and is translocated by organic anion transporters.

PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Suppliers

China 31 France 1 Germany 1 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 10 Global 48
BOC Sciences
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207671-42-9, PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATERelated Search:

2,2'-Bipyridine-5,5'-dicarboxylic acid 3,4-Pyridinedicarboxylic acid Pyridine-2,4,6-tricarboxylic acid 4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester 7,9-DIMETHOXYCARBONYL-2-ETHOXYCARBONYL-5-METHOXY-1H-PYRROLO-[2,3-F]QUINOLINE 7,9-DIMETHOXYCARBONYL-2-ETHOXYCARBONYL-1H-PYRROLO-[2,3-F]QUINOLINE-4,5-DIONE 4,5-DIHYDRO-4,5-DIOXO-1H-PYRROLO[2,3-F]QUINOLINE-2,7,9-TRICARBOXYLIC ACID, 5,5-DIMETHYL KETAL PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Pyrroloquinoline quinone TRIMETHYL 5-HYDROXY-2,3,4-PYRIDINETRICARBOXYLATE Pyrroloquinoline quinone disodium salt

  • PYRIDINE-2,4-DICARBOXYLIC ACID HYDRATE
  • 2,4-PYRIDINEDICARBOXYLIC ACID MONOHYDRATE
  • 2,4-PYRIDINECARBOXYLIC ACID MONOHYDRATE
  • PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE
  • LUTIDINIC ACID MONOHYDRATE
  • 2,4-Pyridinedicarboxylicacid, hydrate (1:1)
  • 2,4-Pyridinedicarboxylic acid Monohydrate 98%
  • 207671-42-9
  • C7H5NO4H2O
  • Building Blocks
  • C7 and C8
  • Heterocyclic Building Blocks
  • Pyridines
  • Building Blocks
  • C7
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • C7 and C8
  • Heterocyclic Building Blocks
  • Pyridines