3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Product Name: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS No.: 63234-80-0
Chemical Name: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Synonyms: 3-(2-Chloroethyl)-6;Risperidone Impurity L;Paliperidone Impurity 26;Risperidone EP IMpurity L;Risperidone Chloro IMpurity;Risperidone Intermediate III;3-(2-Chloro-ethyl)-2-methyl-6,7,8,9-tetrahydro-;Risperidone Impurity 12(Risperidone EP Impurity L);-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one;Risperidone EP Impurity L (Risperidone Chloroethyl Impurity)
CBNumber: CB0359227
Molecular Formula: C11H15ClN2O
Formula Weight: 226.7
MOL File: 63234-80-0.mol

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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Property

Melting point:: 68.5-69.5 °C
Boiling point:: 337 °C
Density: 1.30
Flash point:: 157 °C
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.58±0.70(Predicted)
color: White to Off-White
InChI: InChI=1S/C11H15ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-7H2,1H3
InChIKey: CMWCQQUYLPYOMY-UHFFFAOYSA-N
SMILES: C12CCCCN1C(=O)C(CCCl)=C(C)N=2
CAS DataBase Reference: 63234-80-0(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
HS Code: 2933.99.9701
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2433
Product name: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $124
Updated: 2024/03/01

TCI Chemical

Product number: C2433
Product name: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $374
Updated: 2024/03/01

TRC

Product number: C366155
Product name: 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
Packaging: 5g
Price: $245
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20229
Product name: 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
Packaging: 250g
Price: $625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0020290
Product name: 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO [1,2-A] PYRIMIDINE-4-ONE
Purity: 95.00%
Packaging: 1G
Price: $739.2
Updated: 2021/12/16

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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Palladium hydroxide Toluene Phosphorus oxychloride Ethyl acetate Hydrochloric acid Hydrogen Dichloromethane 2-Acetylbutyrolactone 2-Aminopyridine Isopropyl alcohol PETROLEUM ETHER

Preparation Products

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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Suppliers

Americas 1 Canada 2 China 225 Europe 3 Germany 6 India 39 Japan 2 Switzerland 2 Ukraine 1 United Kingdom 12 United States 38 Global 331

Beijing Whale Technology Corporation Ltd.

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J & K SCIENTIFIC LTD.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Shanghai Feibo Chemical Technology Co., Ltd

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Syntechem Co.,Ltd

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View Lastest Price from 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one manufacturers

Hebei Mojin Biotechnology Co., Ltd

Product: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 63234-80-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-10-30

Sach biotech Co.,Ltd

Product: 3-2-(chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pirido[1,2-a]pirimidin-4-one 63234-80-0
Price: US $300.00-155.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 500kgs/month
Release date: 2024-07-10

Shaanxi Dideu Medichem Co. Ltd

Product: 3-(2-Chloroethyl)-2-Methyl-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-a]-Pyrimidin-4-One 63234-80-0
Price: US $21.00/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-04-30

63234-80-0, 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-oneRelated Search:

Methyl 2-hydroxyethyl cellulose Methyl acrylate 2,6-Lutidine Thiophanate-methyl Azamethiphos 4-Methylpyridine METHYL THIOPHENE-2-CARBOXYLATE Methyl acetate 2-Chloro-5-chloromethylpyridine Kresoxim-methyl Bensulfuron methyl Pirimiphos-methyl Methylparaben Methyl 2,4-Difluorobenzoyl Risperidone IMpurity Desfluoro Risperidone Risperidone Pyrimidinone-N-oxide 6-Fluoro-3-[1-bis-[2-(methyl-6,7,8,9-tetrahydropyridol[1,2,a]pyrimidin-4-one-3-yl)ethyl]piperidinium]benzisoxazole Iodide

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrididine-4-one (intermediate of Risperidone)

3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE

3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE

3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDINO[1,2-A]PYRIMIDINE-4-ONE

3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO(1,2A)PYRIMIDINE-4-ONE

3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRLDO[1,2-A]PYRIMDIN-4-ONE

3-2(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-alpha]pyrimnidin-4-one

3-2(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]PYRIMDIN-4-ONE

8-(CHLOROETHYL)-9-METHYL-6,10-DIAZABICYCLO[4.4.0]DECA-8,10-DIEN-7-ONE

3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-ALPHA]PYRIMIDIN-4-ONE

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2<br>-a]pyrimidin-4-one

3-(2-Chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrimidine-4-one

3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1, 2-A]-PYRIMIDIN-4-ONE ( RISPERIDONE INTERMEDIATE ).

3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]-PYRIMIDIN-4-ONE(RISPERIDONEINTERMEDIATE)

3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]-PYRIDIDINE-4-ONE

3-(2-chloroethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one

Risperidone Intermediate III

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-α]pyrimidin-4-one

3-(2-Chloro-ethyl)-2-methyl-6,7,8,9-tetrahydro-

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrimidin-4-one ,98%

3-(2-Chloroethyl)-6

3-(2-chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]py

Phenyl(4-piperidyl)Methanone3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one

Risperidone Chloro IMpurity

Risperidone EP IMpurity L

3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4Hpyrido[1,2-a]pyrimidin-4-one (piperidopyrimidinone intermediate)

Paliperidone Impurity 26

Risperidone Impurity 12(Risperidone EP Impurity L)

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one &gt

-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Risperidone Impurity L

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one ISO 9001：2015 REACH

Risperidone EP Impurity L (Risperidone Chloroethyl Impurity)

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-...

TIANFU-CHEM - 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, ≥ 98.0%

3-2-(chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pirido[1,2-a]pirimidin-4-one

63234-80-0

63274-80-0

62234-80-0

63274-80-0

C11H15ClN2O

Bases & Related Reagents

Intermediates & Fine Chemicals

Nucleotides

Pharmaceuticals

Intermediates

Nucleotides and Nucleosides

(intermediate of Risperidone)