2-HYDROXY-5-IODO-BENZONITRILE

Application

Product Name: 2-HYDROXY-5-IODO-BENZONITRILE
CAS No.: 685103-95-1
Chemical Name: 2-HYDROXY-5-IODO-BENZONITRILE
Synonyms: 5-IODO-2-HYDROXYBENZONITRILE;2-HYDROXY-5-IODO-BENZONITRILE;Benzonitrile, 2-hydroxy-5-iodo-;2-HYDROXY-5-IODO-BENZONITRILE ISO 9001：2015 REACH
CBNumber: CB0366724
Molecular Formula: C7H4INO
Formula Weight: 245.02
MOL File: 685103-95-1.mol

More

Less

2-HYDROXY-5-IODO-BENZONITRILE Property

Melting point:: 115-117℃
Boiling point:: 321℃
Density: 2.09
Flash point:: 148℃
storage temp.: 2-8°C, protect from light, stored under nitrogen
pka: 6.55±0.18(Predicted)
Appearance: White to light yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: H999953
Product name: 2-Hydroxy-5-iodo-benzonitrile
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 6241CQ
Product name: 2-Hydroxy-5-iodo-benzonitrile
Packaging: 1g
Price: $172
Updated: 2021/12/16

AK Scientific

Product number: 6241CQ
Product name: 2-Hydroxy-5-iodo-benzonitrile
Packaging: 5g
Price: $365
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0049796
Product name: 2-HYDROXY-5-IODO-BENZONITRILE
Purity: 95.00%
Packaging: 1G
Price: $964.14
Updated: 2021/12/16

Chemenu

Product number: CM161684
Product name: 2-hydroxy-5-iodobenzonitrile
Purity: 95%
Packaging: 100g
Price: $1200
Updated: 2021/12/16

More

Less

2-HYDROXY-5-IODO-BENZONITRILE Chemical Properties,Usage,Production

Application

2-Hydroxy-5-iodobenzonitrile is an organic intermediate that can be used to prepare tert-butyl 4-((2-(aminomethyl)-4-iodophenoxy)methyl)piperidine-1-carboxylate. 4-((2-(aminomethyl)-4-iodophenoxy)methyl)piperidine-1-carboxylate and related derivatives have wide applications in medicinal chemistry and organic synthesis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x

Synthesis

(1)Synthesis of 5-iodo-2-hydroxybenzaldehyde oxime

Add 30g 5-iodo-2-hydroxybenzaldehyde to 270ml ethanol, dropwise add 17g hydroxylamine hydrochloride, room temperature stirring overnight, cooling, add water and ethyl acetate, extraction and partitioning, collection of the organic phase, drying, concentration, 23g 5-iodo-2-hydroxybenzaldehyde oxime was obtained.

(2) Synthesis of 2-hydroxy-5-iodobenzonitrile

Add 23g 5-iodo-2-hydroxybenzaldehyde oxime to 190ml acetic anhydride, heat and reflux stirring for 2 hours, concentrate, pour the residue into ice water, add ethyl acetate to extract the liquid, collect the organic phase, dry, concentrate, and get 16g 2-hydroxy-5-iodobenzonitrile separated by column.

2-HYDROXY-5-IODO-BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-HYDROXY-5-IODO-BENZONITRILE Suppliers

China 41 Germany 1 India 1 Switzerland 2 United Kingdom 5 United States 3 Global 53

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9996
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9805
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23884
Advantage: 60

685103-95-1, 2-HYDROXY-5-IODO-BENZONITRILERelated Search:

2-hydroxy-5-iodonicotinic acid 5-Chloro-2-hydroxypyrazine 5-FLUORO-2-HYDROXY-3-NITROPYRIDINE Ethyl 2-hydroxy-5-nitronicotinate 5-bromo-6-hydroxypyridine-3-carbonitrile 2-(4-BROMOPHENYL)PROPAN-2-OL 5-AMINOMETHYL-1H-PYRIDIN-2-ONE 2-HYDROXY-3-PHENYLPYRIDINE 5-IODO-3-(TRIFLUOROMETHYL)-2(1H)-PYRIDINONE 5-BROMO-3-CHLORO-2-HYDROXYPYRIDINE 3-BroMo-6-chloropyridin-2-ol 2-HYDROXY-5-METHYLPYRAZINE 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE 6-CHLORO-1,3-DIHYDRO-2H-IMIDAZO[4,5-B]PYRIDIN-2-ONE 3-Cyano-2-hydroxy-5-iodopyridine 2-HYDROXY-5-IODO-BENZONITRILE 5-iodo-2-methoxybenzonitrile AKOS B029124

5-IODO-2-HYDROXYBENZONITRILE

2-HYDROXY-5-IODO-BENZONITRILE

2-HYDROXY-5-IODO-BENZONITRILE ISO 9001：2015 REACH

Benzonitrile, 2-hydroxy-5-iodo-

685103-95-1

Aromatic Nitriles

Iodine Compounds