ChemicalBook > CAS DataBase List > Ropivacaine hydrochloride

Ropivacaine hydrochloride

Product Name
Ropivacaine hydrochloride
CAS No.
132112-35-7
Chemical Name
Ropivacaine hydrochloride
Synonyms
ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
CBNumber
CB0369811
Molecular Formula
C17H26N2O.ClH.H2O
Formula Weight
328.88
MOL File
132112-35-7.mol
More
Less

Ropivacaine hydrochloride Property

Melting point:
267-269°C
alpha 
D20 -7.28° (c = 2 in water)
storage temp. 
2-8°C
solubility 
H2O: soluble5mg/mL, clear
form 
powder
color 
white to off-white
optical activity
[α]/D -9 to -12, c = 1 in methanol
InChIKey
VSHFRHVKMYGBJL-CKUXDGONSA-N
CAS DataBase Reference
132112-35-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
T,Xi
Risk Statements 
26/27/28-41
Safety Statements 
22-36/37/39-45-39-26
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2933399090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R0283
Product name
Ropivacaine hydrochloride monohydrate
Purity
≥98% (HPLC)
Packaging
10mg
Price
$84.1
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2303
Product name
Ropivacaine hydrochloride
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500MG
Price
$253
Updated
2024/03/01
Sigma-Aldrich
Product number
1605500
Product name
Ropivacaine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Cayman Chemical
Product number
21422
Product name
Ropivacaine (hydrochloride hydrate)
Purity
≥98%
Packaging
25mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
21422
Product name
Ropivacaine (hydrochloride hydrate)
Purity
≥98%
Packaging
50mg
Price
$117
Updated
2024/03/01
More
Less

Ropivacaine hydrochloride Chemical Properties,Usage,Production

Description

(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.

Chemical Properties

White Solid

Uses

Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.

Uses

Anesthetic (local).

Definition

ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.

General Description

Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Ropivacaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ropivacaine hydrochloride Suppliers

Canada 2 China 328 Europe 2 France 1 Germany 2 India 15 Italy 2 South Africa 1 South Korea 1 Switzerland 1 United Kingdom 8 United States 33 Global 396
CHENGHUI PHARMACEUTICAL GROUP LTD
Tel
0531-58897070 15254140813
Fax
0531-58897046
Email
market@jnchsd.com
Country
China
ProdList
213
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Jinan Chenghui Shuangda biological Co., LTD
Tel
0531-58897003 15550412551
Fax
0531-58897003
Email
market@jnchsd.com
Country
China
ProdList
211
Advantage
62
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2871
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Vientiane Tianjin Hengyuan Technology Co., Ltd.
Tel
15722085254
Fax
022-26358246
Email
phytochemical@126.com
Country
China
ProdList
813
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.
Tel
027-59420981,18702770802
Fax
027-83322098
Country
China
ProdList
1975
Advantage
50
Changzhou Josen Pharmaceutical Chemical Co., Ltd.
Tel
0519-85286950 15380036950
Fax
0519-83214720
Email
info@josenchem.com
Country
China
ProdList
55
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Wuhan Kai Lun new material Chemical Co Ltd
Tel
025-87787262
Fax
025-87787262
Country
China
ProdList
496
Advantage
58
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Jinan Jianfeng Chemical Co., Ltd.
Tel
18954159893
Email
demi@pharmachemm.com
Country
China
ProdList
175
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Zhejiang Haiqiang Chemical Co.,Ltd
Tel
0571-86050367 0571-86960370 0571-86050387
Fax
0571-86940780
Email
info@chinahaiqiangchem.com
Country
China
ProdList
462
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
More
Less

View Lastest Price from Ropivacaine hydrochloride manufacturers

Hebei Miaoyin Technology Co.,Ltd
Product
Ropivacaine hydrochloride 132112-35-7
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000
Release date
2023-04-06
HangZhou RunYan Pharma Technology Co.,LTD.
Product
Ropivacaine HCL 132112-35-7
Price
US $0.00-0.00/g
Min. Order
10g
Purity
99% HPLC
Supply Ability
1000kg
Release date
2024-11-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ropivacaine hydrochloride 132112-35-7
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%-101%;EP
Supply Ability
500KGS
Release date
2021-06-17

132112-35-7, Ropivacaine hydrochloride Related Search:

Bupivacaine Ropivacaine 1-AdaMantanethylaMine Topotecan hydrochloride Ropivacaine mesylate N,N-Dimethylformamide Buflomedil hydrochloride Donepezil Hydrochloride Ifosfamide OXONIC ACID POTASSIUM SALT N-(2,6-dimethylphenyl)-N-propylamine Levobupivacaine Propitocaine hydrochloride (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide) Etidocaine Linocaine hydrochloride 2',6'-Pipecoloxylidide Mepivacaine hydrochloride

  • (S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine monohydrochloride monohydrate
  • (S)-1-propyl-2',6'-dimethylanilinoformoxylpiperidine,monohydrochloride,monohydrate
  • (S)-Ropivaxaine hydrochloride
  • (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
  • Ropivacaine hydrochloride
  • (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide Hydrochloride Hydrate
  • LEA-103
  • (S)-ropivacaine hydrochloride hydrate
  • Ropivacaine Hydrochloride (200 mg)
  • 1-methy1-1h-tetrazol-5-ylthiol
  • Ropivacaine Hcl monohydrate
  • (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate
  • Ropivacaine Hydrochloride, USP
  • Ropivacaine-(S) Hydrochloride
  • Ropivacaine HCl.H2O
  • Ropivacaine hydrochloride hydrate
  • LEA-103 HCl
  • 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, hydrochloride (1:1), (2S)-
  • Ropivacaine hydrochloride (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
  • (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate
  • Naropin hydrochloride monohydrate
  • S-ROPIVACAINE HCL
  • (S)-ROPIVACAINE HYDROCHLORIDE
  • ROPIVACAINE HYDROCHLORIDE MONOHYDRATE
  • ROPIVCACAINE HYDROCHLORIDE
  • ROPIVACAINE HCL
  • (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride hydrate
  • Ropivacaine hydrochloride USP/EP/BP
  • Ropivacaine hydrochloride Naropin
  • Ropivacaine Hydrochloride (1605500)
  • Ropivacaine HCl hydrate
  • Ropivacaine HCI
  • 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, hydrochloride, hydrate (1:1:1), (2S)-
  • Ropivacaini Hydrochloridum Monohydricum
  • (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-Piperidinecarboxamide hydrochloride hydrate (1:1:1)
  • Ropivacaine HCl (mono)
  • Ropivacaine HCl H2O IP/USP/BP/EP
  • 132112-35-7
  • 13112-35-7
  • CAS NO.98717-15
  • 132115-35-7
  • C17H26N2OxHCL
  • C17H26N2OHCl
  • C17H26N2OHCLH2O
  • C17H28N2O2HCl
  • C17H26N2O2HClH2O
  • C17H26N2OClHH2O
  • Inhibitors
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
  • 132112-35-7