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Ropivacaine hydrochloride

Product Name
Ropivacaine hydrochloride
CAS No.
132112-35-7
Chemical Name
Ropivacaine hydrochloride
Synonyms
ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
CBNumber
CB0369811
Molecular Formula
C17H26N2O.ClH.H2O
Formula Weight
328.88
MOL File
132112-35-7.mol
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Ropivacaine hydrochloride Property

Melting point:
267-269°C
alpha 
D20 -7.28° (c = 2 in water)
storage temp. 
2-8°C
solubility 
H2O: soluble5mg/mL, clear
form 
powder
color 
white to off-white
optical activity
[α]/D -9 to -12, c = 1 in methanol
InChIKey
VSHFRHVKMYGBJL-CKUXDGONSA-N
CAS DataBase Reference
132112-35-7(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
26/27/28-41
Safety Statements 
22-36/37/39-45-39-26
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2933399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R0283
Product name
Ropivacaine hydrochloride monohydrate
Purity
≥98% (HPLC)
Packaging
10mg
Price
$84.1
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2303
Product name
Ropivacaine hydrochloride
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500MG
Price
$253
Updated
2024/03/01
Sigma-Aldrich
Product number
1605500
Product name
Ropivacaine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Cayman Chemical
Product number
21422
Product name
Ropivacaine (hydrochloride hydrate)
Purity
≥98%
Packaging
25mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
21422
Product name
Ropivacaine (hydrochloride hydrate)
Purity
≥98%
Packaging
50mg
Price
$117
Updated
2024/03/01
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Ropivacaine hydrochloride Chemical Properties,Usage,Production

Description

(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.

Chemical Properties

White Solid

Uses

Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.

Uses

Anesthetic (local).

Definition

ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.

General Description

Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Ropivacaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ropivacaine hydrochloride manufacturers

Apeloa production Co.,Limited
Product
Ropivacaine Hcl 132112-35-7
Price
US $1.00/g
Min. Order
1g
Purity
0.98
Supply Ability
1000
Release date
2024-04-26
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
Mepivacaine hydrochloride 132112-35-7
Price
US $1.00/mg
Min. Order
1000mg
Purity
99
Supply Ability
5ton/month
Release date
2022-02-17
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
Ropivacaine hydrochloride 132112-35-7
Price
US $1.00/mg
Min. Order
1000mg
Purity
99
Supply Ability
5ton/month
Release date
2022-02-18

132112-35-7, Ropivacaine hydrochloride Related Search:

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  • 132112-35-7
  • 13112-35-7
  • CAS NO.98717-15
  • 132115-35-7
  • C17H26N2OxHCL
  • C17H26N2OHCl
  • C17H26N2OHCLH2O
  • C17H28N2O2HCl
  • C17H26N2O2HClH2O
  • C17H26N2OClHH2O
  • Inhibitors
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
  • 132112-35-7