2-Bromo-3-fluorophenol

Product Name: 2-Bromo-3-fluorophenol
CAS No.: 443-81-2
Chemical Name: 2-Bromo-3-fluorophenol
Synonyms: Bromo-3-fluorophenol;3-Fluoro-2-bromophenol;2-BROMO-3-FLUOROPHENOL;Phenol, 2-bromo-3-fluoro-;2-Bromo-3-fluorophenol ISO 9001：2015 REACH
CBNumber: CB0378327
Molecular Formula: C6H4BrFO
Formula Weight: 191
MOL File: 443-81-2.mol

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2-Bromo-3-fluorophenol Property

Boiling point:: 123 °C(Press: 50 Torr)
Density: 1.764±0.06 g/cm3(Predicted)
refractive index: 1.56
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
pka: 7.43±0.10(Predicted)
color: Colorless to Light yellow to Light orange
CAS DataBase Reference: 443-81-2(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 26-36/37/39
RIDADR: UN1760
HazardClass: 8
HS Code: 2908190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5224
Product name: 2-Bromo-3-fluorophenol
Purity: >98.0%(GC)
Packaging: 1g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: B5224
Product name: 2-Bromo-3-fluorophenol
Purity: >98.0%(GC)
Packaging: 5g
Price: $175
Updated: 2025/07/31

TRC

Product number: B685170
Product name: 2-Bromo-3-fluorophenol
Packaging: 10g
Price: $385
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB33796
Product name: 2-Bromo-3-fluorophenol
Packaging: 10g
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 072862
Product name: 2-Bromo-3-fluorophenol
Purity: 95+%
Packaging: 100g
Price: $650
Updated: 2021/12/16

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2-Bromo-3-fluorophenol Chemical Properties,Usage,Production

Description

2-Bromo-3-fluorophenol is a chemical intermediate commonly used in organic synthesis and laboratory research. It can be used to prepare monofluorophenol.

Chemical Properties

light yellow liquid

Uses

2-Bromo-3-fluorophenol has been used as a reactant in the preparation of diaryl ethers.

Synthesis

324769-11-1

443-81-2

1. 120 mL of isopropanol, 200 mL of 6M hydrochloric acid and 81 g (345 mmol) of 1-(methoxymethoxy)-2-bromo-3-fluorophenol were mixed and stirred for 2.5 hours at room temperature. 2. Upon completion of the reaction, the reaction mixture was partitioned. 400 ml of methyl tert-butyl ether and 120 ml of 5N sodium hydroxide were added. 3. The organic phase was separated, washed with saturated aqueous sodium chloride solution and then dried over anhydrous sodium sulfate. 4. The dried organic phase is concentrated under pressure to give an oily residue. 5. purify the residue by silica gel column chromatography and collect the fraction containing 2-bromo-3-fluorophenol. 6. Concentrate the combined fractions under pressure to give 55.1 g (84% yield) of the target compound 2-bromo-3-fluorophenol as a colorless oil.

References

[1] Patent: EP1204660, 2004, B1. Location in patent: Page 19

2-Bromo-3-fluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-3-fluorophenol Suppliers

Americas 1 China 142 Europe 2 Germany 1 India 3 Japan 1 Ukraine 1 United Kingdom 9 United States 22 Global 182

J & K SCIENTIFIC LTD.

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Energy Chemical

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Accela ChemBio Co.,Ltd.

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View Lastest Price from 2-Bromo-3-fluorophenol manufacturers

Honest Joy Holdings Limited

Product: 2-Bromo-3-fluorophenol 443-81-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.5%
Supply Ability: 100 tons
Release date: 2022-02-21

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-3-fluorophenol 443-81-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-3-fluorophenol 443-81-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

443-81-2, 2-Bromo-3-fluorophenolRelated Search:

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Bromo-3-fluorophenol

2-BROMO-3-FLUOROPHENOL

3-Fluoro-2-bromophenol

Phenol, 2-bromo-3-fluoro-

2-Bromo-3-fluorophenol ISO 9001：2015 REACH

443-81-2

441-81-2

Aromatic Phenols

pharmacetical

Phenol&Thiophenol&Mercaptan

Aromatics, Miscellaneous Reagents