4-Bromo-2-fluorophenol

Product Name: 4-Bromo-2-fluorophenol
CAS No.: 2105-94-4
Chemical Name: 4-Bromo-2-fluorophenol
Synonyms: 4-Bromo-2-fluorophen;4-Brom-2-Fluorphenol;2-Fluor-4 bromophenol;2-Fluoro-4-BroMophonel;2-Fluoro-4-Bromophenol;4-BROMO-2-FLUOROPHENOL;2-Bromo-2-fluorophenol;4-Bromo-2-fluorophenol98%;Phenol, 4-bromo-2-fluoro-;4-Bromo-2-fluorophenol >
CBNumber: CB6257615
Molecular Formula: C6H4BrFO
Formula Weight: 191
MOL File: 2105-94-4.mol

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4-Bromo-2-fluorophenol Property

Boiling point:: 79 °C/7 mmHg (lit.)
Density: 1.744 g/mL at 25 °C (lit.)
refractive index: n20/D 1.566(lit.)
Flash point:: 210 °F
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
pka: 8.14±0.18(Predicted)
Specific Gravity: 1.744
color: Clear colorless to brown
BRN: 1861281
InChI: InChI=1S/C6H4BrFO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H
InChIKey: RYVOZMPTISNBDB-UHFFFAOYSA-N
SMILES: C1(O)=CC=C(Br)C=C1F
CAS DataBase Reference: 2105-94-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-37/39-36/37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29071990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 316296
Product name: 4-Bromo-2-fluorophenol
Purity: 98%
Packaging: 5g
Price: $25
Updated: 2023/01/07

Sigma-Aldrich

Product number: 316296
Product name: 4-Bromo-2-fluorophenol
Purity: 98%
Packaging: 25g
Price: $60.8
Updated: 2023/01/07

TCI Chemical

Product number: B1835
Product name: 4-Bromo-2-fluorophenol
Purity: >98.0%(GC)
Packaging: 5g
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: B1835
Product name: 4-Bromo-2-fluorophenol
Purity: >98.0%(GC)
Packaging: 25g
Price: $92
Updated: 2025/07/31

TRC

Product number: B692828
Product name: 4-Bromo-2-fluorophenol
Packaging: 5g
Price: $75
Updated: 2021/12/16

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4-Bromo-2-fluorophenol Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLORLESS TO BROWNISH LIQUID

Uses

4-Bromo-2-fluorophenol can be used as a starting material for the synthesis of:

4-Bromo-2-fluoro-6-iodoanisole via iodination and methylation.
2-Phenylpyran-4-ones for active cyclooxygenase-2 inhibitor evaluation.
1,4-Disubstituted 3-cyano-2-pyridones.
Dicationic imidazolium-based compounds.

Synthesis

367-12-4

2105-94-4

Example 5: Preparation of methyl 2-[4-(4-bromo-2-fluorophenoxy)phenoxy]propionate (STR29) 1. 2-Fluorophenol (22.4 g, 0.2 mol) was dissolved in dichloromethane (250 mL) under ice bath conditions and cooled to about 3 °C. 2. 2. bromine (31.97 g, 0.2 mol) was added slowly, keeping the reaction temperature at ice bath conditions. 3. the reaction mixture was stirred at ice bath temperature for 2 hours, followed by continued stirring at room temperature for 1 hour. 4. the reaction mixture was quenched by pouring into water (600 mL) containing excess sodium bisulfite. 5. The organic phase was separated and the aqueous phase was washed with additional dichloromethane (200 mL). 6. The organic extracts were combined, washed with saturated sodium bicarbonate solution and subsequently dried over anhydrous magnesium sulfate. 7. The solvent was removed by evaporation to afford the target product 2-fluoro-4-bromophenol as a colorless oil (34.5 g, 90% yield). 8. The structure of the product was confirmed to be as expected by NMR hydrogen spectroscopy (CDCl3).

References

[1] Patent: US4642338, 1987, A
[2] Patent: US4725683, 1988, A
[3] Patent: US4808750, 1989, A
[4] Patent: US4550192, 1985, A
[5] Chemistry - A European Journal, 2017, vol. 23, # 5, p. 1044 - 1047

4-Bromo-2-fluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-2-fluorophenol Suppliers

Americas 1 Belgium 2 CHINA 343 Europe 3 France 2 Germany 5 India 11 Italy 1 Japan 5 Slovakia 1 Switzerland 3 Ukraine 2 United Kingdom 21 United States 51 Global 451

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

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View Lastest Price from 4-Bromo-2-fluorophenol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Bromo-2-fluorophenol 2105-94-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Bromo-2-fluorophenol 2105-94-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-21

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Bromo-2-fluorophenol 2105-94-4
Price: US $10.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-23

2105-94-4, 4-Bromo-2-fluorophenolRelated Search:

3-Fluorophenol 3-Trifluoromethylphenol 2-Bromophenol 4-Bromo-2-fluorobenzoic acid 4-Bromophenol 4-Fluorophenol 4-Trifluoromethylphenol 3-Bromophenol 4-BROMO-2-CHLORO-6-FLUOROPHENOL 4-BROMO-2-CHLORO-6-FLUOROANISOLE 4-Bromo-2-fluoro-6-nitrophenol 4-Bromo-2,5-difluoroanisole 2-(4'-BROMO-2'-FLUOROPHENOXY)PROPANE 4-Bromo-2,6-difluoroanisole 4-BROMO-2,6-DIFLUOROPHENOL 4-Bromo-2-fluoroanisole 2,4-DIBROMO-6-FLUOROPHENOL Bromine

4-BROMO-2-FLUOROPHENOL

2-Fluoro-4-Bromophenol

4-Bromo-2-fluorophenol 98%

4-Bromo-2-fluorophenol98%

4-Bromo-2-fluorophenol, 97+%

4-Bromo-2-fluorophen

4-BroMo-2-fluorophenol, 98% 5GR

2-Fluoro-4-BroMophonel

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2-Fluor-4 bromophenol

Phenol, 4-bromo-2-fluoro-

4-Bromo-2-fluorophenol ISO 9001：2015 REACH

4-Brom-2-Fluorphenol

2-Bromo-2-fluorophenol

2105-94-4

2105-94-9

2015-94-4

2195-94-4

BrC6H3FOH

C6H4BrFO

Building Blocks for Liquid Crystals

Phenols (Building Blocks for Liquid Crystals)

Building Blocks

Organic Building Blocks

Oxygen Compounds

Phenols

alcohol| alkyl bromide|alkyl Fluorine

Building Blocks for Liquid Crystals

Functional Materials

Phenols (Building Blocks for Liquid Crystals)

Organic Building Blocks

Oxygen Compounds

Fluorobenzene

Phenol&Thiophenol&Mercaptan

Bromine Compounds

Fluorine Compounds

Phenols

Aromatic Phenols

Fluorobenzene Series

bc0001