ChemicalBook > CAS DataBase List > 2-Hydroxyisobutyric acid

2-Hydroxyisobutyric acid

Product Name
2-Hydroxyisobutyric acid
CAS No.
594-61-6
Chemical Name
2-Hydroxyisobutyric acid
Synonyms
2-HYDROXY-2-METHYLPROPANOIC ACID;2-hydroxyisobutyrate;ALPHA-HYDROXYISOBUTYRIC ACID;α-Hydroxyisobutyric acid;|á-Hydroxyisobutyric acid;2-HYDROXY-2-METHYLPROPIONIC ACID;Propanoic acid, 2-hydroxy-2-methyl-;(CH3)2COHCOOH;METHYL LACTIC ACID;RARECHEM AL BO 0199
CBNumber
CB0379920
Molecular Formula
C4H8O3
Formula Weight
104.1
MOL File
594-61-6.mol
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2-Hydroxyisobutyric acid Property

Melting point:
76-80 °C(lit.)
Boiling point:
84 °C1.5 mm Hg(lit.)
Density 
11412
refractive index 
1.4761 (estimate)
Flash point:
114°C/12mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
water: soluble10%, clear to very slightly hazy, colorless
pka
pK1:3.717 (25°C,μ=0.1)
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble in water, ether, alcohol, methanol and hot benzene.
BRN 
1744739
LogP
-0.360
CAS DataBase Reference
594-61-6(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, 2-hydroxy-2-methyl-(594-61-6)
EPA Substance Registry System
Propanoic acid, 2-hydroxy-2-methyl- (594-61-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/37/38
Safety Statements 
26-39-25-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29181980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
323594
Product name
α-Hydroxyisobutyric acid
Purity
99%
Packaging
25g
Price
$56.5
Updated
2024/03/01
Sigma-Aldrich
Product number
164976
Product name
α-Hydroxyisobutyric acid
Purity
98%
Packaging
25g
Price
$41.6
Updated
2024/03/01
TCI Chemical
Product number
M0360
Product name
2-Hydroxyisobutyric Acid
Purity
>98.0%(T)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
M0360
Product name
2-Hydroxyisobutyric Acid
Purity
>98.0%(T)
Packaging
100g
Price
$65
Updated
2024/03/01
Alfa Aesar
Product number
A13146
Product name
2-Hydroxyisobutyric acid, 99% (dry wt.), water <2%
Packaging
25g
Price
$29.65
Updated
2024/03/01
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2-Hydroxyisobutyric acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white needle-like crystals or

Uses

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Uses

α-Hydroxyisobutyric acid was used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Uses

2-Hydroxyisobutyric acid is used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Definition

ChEBI: A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1488, 1958 DOI: 10.1021/jo01104a022

General Description

α-Hydroxyisobutyric acid (2-hydroxyisobutyric acid) is the building block for polymer synthesis. It forms complexes with Eu(III) and has been studied by time resolved fluorescence spectroscopy.

2-Hydroxyisobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Hydroxyisobutyric acid Suppliers

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View Lastest Price from 2-Hydroxyisobutyric acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Hydroxyisobutyric acid 594-61-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-12
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Hydroxyisobutyric acid 594-61-6
Price
US $55.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-21
Hebei Weibang Biotechnology Co., Ltd
Product
2-Hydroxyisobutyric acid 594-61-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-14

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