ISOXAFLUTOLE

Product Name: ISOXAFLUTOLE
CAS No.: 141112-29-0
Chemical Name: ISOXAFLUTOLE
Synonyms: MERLIN;BALANCE;Ift cpd;Hsdb 7275;Isoxautole;Exp 31130a;SOXAFLUTOLE;ISOXAFLUTOLE;Isoxaflutole 0;Isoxaflutole [iso]
CBNumber: CB0382227
Molecular Formula: C15H12F3NO4S
Formula Weight: 359.32
MOL File: 141112-29-0.mol

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ISOXAFLUTOLE Property

Melting point:: 138-138.5° (Cain); mp 140°
Boiling point:: 575.1±50.0 °C(Predicted)
Density: 1.59
Flash point:: >130 °C
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform, DCM, Ethyl Acetate, Methanol
pka: -4.29±0.50(Predicted)
form: Solid
color: White
BRN: 8344543
LogP: 2.320
CAS DataBase Reference: 141112-29-0
EPA Substance Registry System: Isoxaflutole (141112-29-0)

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Safety

Hazard Codes: Xn,N
Risk Statements: 50/53-63
Safety Statements: 36/37-60-61
RIDADR: UN3077 9/PG 3
WGK Germany: 3
Hazardous Substances Data: 141112-29-0(Hazardous Substances Data)
Toxicity: LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 46437
Product name: Isoxaflutole
Purity: PESTANAL?, analytical standard
Packaging: 100mg
Price: $147
Updated: 2024/03/01

TRC

Product number: I918140
Product name: Isoxaflutole
Packaging: 10mg
Price: $580
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 71008
Product name: Isoxaflutole
Packaging: 2.5mg
Price: $675
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AGR0000257
Product name: ISOXAFLUTOLE
Purity: 95.00%
Packaging: 5MG
Price: $496
Updated: 2021/12/16

Crysdot

Product number: CD11263309
Product name: (5-Cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone
Purity: 95+%
Packaging: 1g
Price: $89
Updated: 2021/12/16

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ISOXAFLUTOLE Chemical Properties,Usage,Production

Description

Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).

Uses

Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.

Uses

Herbicide.

Definition

ChEBI: Isoxaflutole is a member of the class of isoxazoles that is 1,2-oxazole substituted by a 2-(methanesulfonyl)-4-(trifluoromethyl)benzoyl group and a cyclopropyl group at positions 4 and 5, respectively. It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor which is used as a herbicide for weed control in maize and sugarcane. It has a role as an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor, a proherbicide and an agrochemical. It is a member of cyclopropanes, a member of isoxazoles, an aromatic ketone, a member of (trifluoromethyl)benzenes and a sulfone.

Pharmacology

Isoxaflutole is readily taken up by roots and foliar tissues and then rapidly degraded to a diketonitrile derivative (2-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)- 3-oxo propanenitrile) , which is translocated throughout the plant via xylem and phloem (2,3,6,8). It is this metabolite that inhibits HPPD (7), thereby depleting the plastoquinone pools in developing leaves. Plastoquinone is a cofactor in the desaturation of phytoene, levels of which increase in bleached leaves, concomitant with decreases in colored carotenoids (6). Although bleaching is the primary symptom associated with HPPD inhibition, subsequent growth suppression and necrosis are also believed to be a consequence (8).
Isoxaflutole also degrades to the diketonitrile derivative in the soil (3,8). The half-life of isoxaflutole in soil is dependent on soil type, pH, and moisture, ranging from 12 hours to 3 days under laboratory conditions (8). The physicochemical properties of isoxaflutole and of diketonitrile play an important role in both soil and herbicidal activity and selectivity (8).

ISOXAFLUTOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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ISOXAFLUTOLE Suppliers

China 115 France 1 Germany 2 India 1 Japan 2 Switzerland 1 United States 8 USA 1 Global 131

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
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Aladdin Scientific

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United States Biological

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Riedel-de Haen AG

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AccuStandard Inc

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ChemService Inc.

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A.P.T. Labs, Inc.

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Crescent Chemical Co., Inc.

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ProdList: 4597
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View Lastest Price from ISOXAFLUTOLE manufacturers

Career Henan Chemical Co

Product: ISOXAFLUTOLE 141112-29-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-23

141112-29-0, ISOXAFLUTOLERelated Search:

METHYL ISOXAZOLE-5-CARBOXYLATE 1,2-oxazol-3-ylMethanaMine hydrochloride ISOXAZOLIDIN-3-ONE ISOXAZOLE-5-CARBOXYLIC ACID 5-Isoxazolecarboxylicacid,ethylester(9CI) ISOXAZOLO[5,4-B]PYRIDIN-3-YLAMINE Isoxazol-4-ylmethanamine oxalate Ifosfamide ACIVICIN Clomazone Penoxsulam Fluroxypyr metamifop theta-Cypermethrin Isoxazole 3-AMINOISOXAZOLO[4,5-B]PYRAZINE Isoxazole-4-boronicacid C-ISOXAZOL-5-YL-METHYLAMINE HYDROCHLORIDE

MERLIN

BALANCE

ISOXAFLUTOLE

ISOXAFLUTOLE 45% SOLUTION

5-cyclopropyl-4-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]isoxazole

isoxaflutole (bsi, pa iso)

isoxaflutole (ISO) 5-cyclopropyl-1,2-oxazol-4-yl α,α,α-trifluoro-2-mesyl-p-tolyl ketone

Isoxaflutole 0

Isoxautole

(5-Cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone

Einecs annex I index 606-054-00-7

Exp 31130a

Hsdb 7275

Ift cpd

Isoxaflutole [iso]

Isoxaflutole 100mg [141112-29-0]

(5-Cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone

Isoxaflutole 97% TC

Isoxaflutole pesticide

Isoxautole Solution,100ppm

SOXAFLUTOLE

Isoxaflutole@100 μg/mL in AcCN

Methanone, (5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]-

5-cyclopropyl-4-[2-methanesulfonyl-4-(trifluorome thyl)benzoyl]-1,2-oxazole

Isoxaflutole Solution in Acetonitrile, 1000μg/mL

Isoxaflutole Solution in Methanol

Isoxaflutole Solution in Acetonitrile

Isoxaflutole in Acetone

C14481000 Isoxaflutole

141112-29-0