2,6-Dichloropyridin-3-amine
- Product Name
- 2,6-Dichloropyridin-3-amine
- CAS No.
- 62476-56-6
- Chemical Name
- 2,6-Dichloropyridin-3-amine
- Synonyms
- BUTTPARK 43\57-50;3-Amino-2,6-dichL;TIMTEC-BB SBB005502;2,6-dichloro-3-pyridylamine;2,6-Dichloro-3-pyridinamine;2,6-DICHLOROPYRIDIN-3-AMINE;2,6-DICHLORO-3-AMINOPYRIDINE;3-AMINO-2,6-DICHLOROPYRIDINE;2,6-Dichloropyridine-3-amine;3-Pyridinamine, 2,6-dichloro-
- CBNumber
- CB0382676
- Molecular Formula
- C5H4Cl2N2
- Formula Weight
- 163
- MOL File
- 62476-56-6.mol
2,6-Dichloropyridin-3-amine Property
- Melting point:
- 122 °C
- Boiling point:
- 268.76°C (rough estimate)
- Density
- 1.5462 (rough estimate)
- refractive index
- 1.6300 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- -0.01±0.10(Predicted)
- color
- White to Gray to Brown
- InChI
- InChI=1S/C5H4Cl2N2/c6-4-2-1-3(8)5(7)9-4/h1-2H,8H2
- InChIKey
- MJVZSRZTBDMYLX-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(Cl)=CC=C1N
- CAS DataBase Reference
- 62476-56-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 3-Amino-2,6-dichloropyridine(62476-56-6)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-43-41-22
- Safety Statements
- 26-36/37/39-37/39-36-28
- RIDADR
- 2811
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H317May cause an allergic skin reaction
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 706361
- Product name
- 3-Amino-2,6-dichloropyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $80.2
- Updated
- 2022/05/15
- Product number
- A1580
- Product name
- 3-Amino-2,6-dichloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- A1580
- Product name
- 3-Amino-2,6-dichloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $226
- Updated
- 2025/07/31
- Product number
- A576633
- Product name
- 3-Amino-2,6-dichloropyridine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 024847
- Product name
- 3-Amino-2,6-dichloropyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $205
- Updated
- 2021/12/16
2,6-Dichloropyridin-3-amine Chemical Properties,Usage,Production
Chemical Properties
crystal
Uses
2,6-Dichloro-3-pyridinamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Definition
ChEBI: 2,6-Dichloropyridin-3-amine is a chloropyridine.
Synthesis
16013-85-7
62476-56-6
General procedure for the synthesis of 2,6-dichloro-3-aminopyridine from 2,6-dichloro-3-nitropyridine: To a solution of 2,6-dichloro-3-nitropyridine (100 g, 0.518 mol) in acetic acid (1 L) was added powdered iron (86.49 g, 1.555 mol) in batches. The reaction mixture was stirred at room temperature for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) system (petroleum ether/ethyl acetate = 8:2) to confirm the completion of the reaction. After completion of the reaction, the reaction mixture was concentrated under high vacuum. The crude product was dissolved in water (1 L) and ethyl acetate (EtOAc, 2 L). The pH of the aqueous solution was adjusted to 6.5 using sodium carbonate (Na2CO3) powder under stirring.The mixture was filtered through diatomaceous earth (Celite), the organic layer was separated, dried with anhydrous sodium sulfate and concentrated to give 2,6-dichloro-3-aminopyridine (80 g, 95% yield) as a white solid.1H NMR (400 MHz, DMSO-d6) δppm : 7.14-7.20 (2H, m), 5.78 (2H, s).
Purification Methods
Recrystallise it from water. [Beilstein 22 III/IV 4093.]
References
[1] Patent: WO2014/22349, 2014, A1. Location in patent: Paragraph 00221-00222
[2] Molecules, 2007, vol. 12, # 2, p. 218 - 230
[3] Journal of Organic Chemistry, 2011, vol. 76, # 23, p. 9841 - 9844
[4] Patent: WO2016/103097, 2016, A1. Location in patent: Page/Page column 47
[5] Journal of Heterocyclic Chemistry, 1984, vol. 21, # 3, p. 673 - 679
2,6-Dichloropyridin-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dichloropyridin-3-amine Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 2,6-Dichloropyridin-3-amine manufacturers
- Product
- 2,6-Dichloropyridin-3-amine 62476-56-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 2,6-Dichloropyridin-3-amine 62476-56-6
- Price
- US $21.00/KG
- Min. Order
- 1KG
- Purity
- 99.0% min
- Supply Ability
- 100 tons
- Release date
- 2021-04-13
- Product
- 2,6-Dichloropyridin-3-amine 62476-56-6
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08