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Tolperisone

Product Name
Tolperisone
CAS No.
728-88-1
Chemical Name
Tolperisone
Synonyms
mydeton;Mideton;Mydetone;AKOS 91983;NSC 107321;TOLPERISONE;dl-Tolperisone;Atmosgen free base;Besnoline free base;Tolperisone USP/EP/BP
CBNumber
CB0393580
Molecular Formula
C16H23NO
Formula Weight
245.36
MOL File
728-88-1.mol
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Tolperisone Property

Melting point:
176.5°C
Boiling point:
388.33°C (rough estimate)
Density 
0.9672 (rough estimate)
refractive index 
1.5500 (estimate)
pka
8.47±0.10(Predicted)
CAS DataBase Reference
728-88-1(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0008765
Product name
TOLPERISONE
Purity
95.00%
Packaging
1KG
Price
$6985.44
Updated
2021/12/16
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Tolperisone Chemical Properties,Usage,Production

Originator

Tolperisone hydrochloride,Shanghai Abochem Chemical Co.

Definition

ChEBI: 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone is an aromatic ketone.

Manufacturing Process

To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.

brand name

Tolperisone Hydrochloride is JAN.

Therapeutic Function

Muscle relaxant, Vasodilator

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 42, p. 1676, 1994 DOI: 10.1248/cpb.42.1676

Tolperisone Preparation Products And Raw materials

Raw materials

Preparation Products

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Tolperisone Suppliers

TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9577
Advantage
60
Foshan DaoQi Biological Co., Ltd.
Tel
18062666947
Fax
18062666959
Email
2355880548@qq.com
Country
China
ProdList
4228
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34553
Advantage
58
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View Lastest Price from Tolperisone manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Tolperisone 728-88-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

728-88-1, TolperisoneRelated Search:


  • AKOS 91983
  • 1-piperidino-2-methyl-3-(p-tolyl)-3-propanone
  • 2,4’-dimethyl-3-piperidino-propiophenon
  • 2-methyl-3-piperidino-1-p-tolylpropan-1-one
  • mydeton
  • TOLPERISONE
  • α,4'-Dimethyl-β-piperidinopropiophenone
  • 2-methyl-1-(4-methylphenyl)-3-piperidin-1-yl-propan-1-one
  • 2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one
  • 2-methyl-1-(4-methylphenyl)-3-piperidino-propan-1-one
  • 1-Propanone, 2-Methyl-1-(4-Methylphenyl)-3-(1-piperidinyl)-
  • 2'4-Dimethyl-3-PiperidylPropiophenone
  • 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)- (9CI)
  • dl-Tolperisone
  • Mideton
  • Mydetone
  • NSC 107321
  • Propiophenone, 2,4'-dimethyl-3-piperidino- (7CI, 8CI)
  • Tolperisone (base and/or unspecified salts)
  • 2,4'-Dimethyl-3-piperidinopropiophenone
  • 2-Methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone
  • Tolperisone USP/EP/BP
  • TolperisoneQ: What is Tolperisone Q: What is the CAS Number of Tolperisone Q: What is the storage condition of Tolperisone Q: What are the applications of Tolperisone
  • 728-88-1 Tolperisone C16H23NO
  • Atmosgen free base
  • Besnoline free base
  • Tolperisone free base
  • 2-methyl-3-(piperidin-1-yl)-1-(p-tolyl)propan-1-one
  • 728-88-1