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Diethyl cyanomethylphosphonate

Product Name
Diethyl cyanomethylphosphonate
CAS No.
2537-48-6
Chemical Name
Diethyl cyanomethylphosphonate
Synonyms
2-Diethoxyphosphorylacetonitrile;cyanomethyL;DEPAN;NSC 407826;Diethyl cyanomethylp;LABOTEST-BB LT00233137;Diethyl cyanomethylphosphote;DIETHYL CYANOMETHYLPHOSPHONATE;(DIETHYLPHOSPHONO)ACETONITRILE;Diethoxyphosphinylacetonitrile
CBNumber
CB0397573
Molecular Formula
C6H12NO3P
Formula Weight
177.14
MOL File
2537-48-6.mol
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Diethyl cyanomethylphosphonate Property

Boiling point:
101-102 °C0.4 mm Hg(lit.)
Density 
1.095 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.434(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
Chloroform (Soluble), Methanol (Slightly)
form 
Liquid
color 
Clear colorless to light yellow
Specific Gravity
1.1261.095
Water Solubility 
Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride.
BRN 
1772981
InChI
InChI=1S/C6H12NO3P/c1-3-9-11(8,6-5-7)10-4-2/h3-4,6H2,1-2H3
InChIKey
KWMBADTWRIGGGG-UHFFFAOYSA-N
SMILES
P(CC#N)(=O)(OCC)OCC
CAS DataBase Reference
2537-48-6(CAS DataBase Reference)
NIST Chemistry Reference
Diethyl cyanomethylphosphonate(2537-48-6)
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Safety

Hazard Codes 
Xi,Xn,C
Risk Statements 
38-36/37/38-20/21/22-34-36/38
Safety Statements 
26-28-36/37/39-23-45-27-36/37-9
RIDADR 
UN 1760 8/PG 2
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29310095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D91705
Product name
Diethyl cyanomethylphosphonate
Purity
98%
Packaging
10g
Price
$84.5
Updated
2024/03/01
Sigma-Aldrich
Product number
D91705
Product name
Diethyl cyanomethylphosphonate
Purity
98%
Packaging
50g
Price
$229
Updated
2024/03/01
TCI Chemical
Product number
C1430
Product name
Diethyl Cyanomethylphosphonate
Purity
>98.0%(GC)
Packaging
5g
Price
$18
Updated
2024/03/01
TCI Chemical
Product number
C1430
Product name
Diethyl Cyanomethylphosphonate
Purity
>98.0%(GC)
Packaging
25g
Price
$67
Updated
2024/03/01
Alfa Aesar
Product number
A10218
Product name
Diethyl cyanomethylphosphonate, 98+%
Packaging
25g
Price
$91.65
Updated
2024/03/01
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Diethyl cyanomethylphosphonate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.

Uses

Wittig reagent.

Biological Functions

Diethyl cyanomethylphosphonate can be used to inhibit and/0r prevent the growth of undesirable algae, bacteria, fungi, yeast, and other microorganisms.

General Description

Diethyl cyanomethylphosphonate is a useful chemical and medical intermediate, which can be used as raw material to synthesize nitrogen-haloamine precursor AEP-ADCT containing triazine-phosphate group

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View Lastest Price from Diethyl cyanomethylphosphonate manufacturers

Hebei Duling International Trade Co. LTD
Product
Diethyl cyanomethylphosphonate 2537-48-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000tons
Release date
2022-10-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Diethyl cyanomethylphosphonate 2537-48-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Diethyl cyanomethylphosphonate 2537-48-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

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  • C6H12NO3P
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  • C-C Bond Formation
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  • 2537-48-6