ChemicalBook > CAS DataBase List > 3-Methylthiopropanol

3-Methylthiopropanol

Product Name
3-Methylthiopropanol
CAS No.
505-10-2
Chemical Name
3-Methylthiopropanol
Synonyms
1-Propanol, 3-(methylthio)-;METHIONOL;3-(METHYLTHIO)-1-PROPANOL;3-(METHYLTHIO)PROPAN-1-OL;3-Methionol;3-(methylsulfanyl)propanol;Methinol;FEMA 3415;Methionol>Methionol ,98%
CBNumber
CB0400208
Molecular Formula
C4H10OS
Formula Weight
106.19
MOL File
505-10-2.mol
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3-Methylthiopropanol Property

Melting point:
-100°C (estimate)
Boiling point:
89-90 °C13 mm Hg(lit.)
Density 
1.03 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.49(lit.)
FEMA 
3415 | 3-(METHYLTHIO)PROPANOL
Flash point:
195 °F
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
14.87±0.10(Predicted)
form 
liquid (estimate)
Specific Gravity
1.03
color 
Clear Colorless to Light Yellow
Odor
at 0.10 % in propylene glycol. sulfurous onion sweet soup vegetable
Odor Type
meaty
biological source
synthetic
JECFA Number
461
LogP
0.40
CAS DataBase Reference
505-10-2(CAS DataBase Reference)
NIST Chemistry Reference
1-Propanol, 3-(methylthio)-(505-10-2)
EPA Substance Registry System
Methionol (505-10-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-24/25-36/37/39
RIDADR 
UN 3334
WGK Germany 
3
TSCA 
Yes
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W341509
Product name
3-(Methylthio)-1-propanol
Purity
≥98%, FG
Packaging
1 unit
Price
$55.5
Updated
2025/07/31
Sigma-Aldrich
Product number
W341509
Product name
3-(Methylthio)-1-propanol
Purity
≥98%, FG
Packaging
1 unit
Price
$55.5
Updated
2025/07/31
Sigma-Aldrich
Product number
W341509
Product name
3-(Methylthio)-1-propanol
Purity
≥98%, FG
Packaging
100g
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
W341509
Product name
3-(Methylthio)-1-propanol
Purity
≥98%, FG
Packaging
1kg
Price
$614
Updated
2025/07/31
Sigma-Aldrich
Product number
W341509
Product name
3-(Methylthio)-1-propanol
Purity
≥98%, FG
Packaging
5kg
Price
$1490
Updated
2025/07/31
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3-Methylthiopropanol Chemical Properties,Usage,Production

Description

3-(Methylthio)propanol has a powerful sweet soup or meat-like odor and flavor in high dilution. May be prepared from propylene chlorhydrin and sodium hydrosulfide.

Chemical Properties

Colorless Liquid

Chemical Properties

3-(Methylthio)propanol has a powerful, sweet, soup or meat-like odor and flavor in high dilution.

Occurrence

Reported found in fermented soy sauce, tomatoes, grape wines, apple, melon, pineapple, asparagus, rye bread, cheeses, cured pork, beer, cognac, malt whiskey, cider, sherry, coffee, litchi, shrimp and apple brandy

Uses

3-(Methylthio)-1-propanol is used in the meat essence composition.

Uses

3-Methylthiopropanol is used in the meat essence composition.It is also used in meat, potato, and cheese flavorings.

Preparation

From propylene chlorhydrin and sodium hydrosulfide

Definition

ChEBI: An alkyl sulfide that is propan-1-ol substituted by a methylsulfanyl group at position 3. It is a volatile compound found in wines and produced during fermentation.

Aroma threshold values

Detection: 0.2 ppb. Aroma characteristics at 1.0%: sulfurous, savory, vegetative raw potato-like, fresh tomato, metallic anchovy-like with some onion and garlic nuances

Taste threshold values

Taste characteristics at 0.5 ppm: metallic, tomato, potato, anchovy-like with savory brothy and malt-like nuances.

Synthesis Reference(s)

Tetrahedron, 48, p. 5933, 1992 DOI: 10.1016/S0040-4020(01)90183-8

General Description

3-(Methylthio)-1-propanol is a volatile sulfur flavor compound mainly found in wine and soy sauce.

Synthesis

3268-49-3

505-10-2

An excess of 10% sodium borohydride (NaBH4), a reducing agent, was slowly added to 30 mL of the selected solvent at 0°C to form a suspension. Subsequently, 10 g of 3-methylthiopropionaldehyde (MMP) was slowly added dropwise to the above suspension at a temperature controlled below 20 °C. After the dropwise addition, the reaction mixture was stirred at room temperature for 3 to 12 hours. Upon completion of the reaction, HCl solution was added to the reaction solution for hydrolysis. After hydrolysis, water was removed from the reaction solution by evaporation under reduced pressure. The reaction solution was filtered to remove the sodium chloride generated by hydrolysis and the residue was washed with 10 mL of cold methanol solution to further extract the product 3-methylthiopropanol. Finally, methanol was removed by evaporation of the combined mixed solution and filtrate to give pure 3-methylthiopropanol. Note: The solvent may be selected from dichloromethane (CH2Cl2), dimethylformamide (DMF), methanol, 3-methylthiopropanol (or a solvent mixture thereof with a diluent, referred to as "3-methylthiopropanol"), tetrahydrofuran (THF), or water (H2O), and the concentration of 3-methylthiopropanal (MMP) is 100 percent .

References

[1] Journal of Organic Chemistry, 2000, vol. 65, # 26, p. 8933 - 8939
[2] Patent: CN107245043, 2017, A. Location in patent: Paragraph 0032; 0033; 0034; 0035; 0036

3-Methylthiopropanol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Methylthiopropanol manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-Methylthiopropanol 505-10-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-27
Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Methylthiopropanol 505-10-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-25
Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Methylthiopropanol 505-10-2
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-11-18

505-10-2, 3-MethylthiopropanolRelated Search:


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