ChemicalBook > CAS DataBase List > 2-AMINO-3-CHLORO-5-NITROPYRIDINE

2-AMINO-3-CHLORO-5-NITROPYRIDINE

Product Name
2-AMINO-3-CHLORO-5-NITROPYRIDINE
CAS No.
22353-35-1
Chemical Name
2-AMINO-3-CHLORO-5-NITROPYRIDINE
Synonyms
3-Chloro-5-nitro-2-pyridinamine;3-chloro-5-nitropyridin-2-amine;2-AMINO-3-CHLORO-5-NITROPYRIDINE;2-amino 5-nitro 3-chloro pyridine;2-Pyridinamine, 3-chloro-5-nitro-;3-Chloro-5-nitro-pyridin-2-ylamine;2-AMINO-3-CHLORO-5-NITROPYRIDINE, 95+%;Pyridine,2-amino-3-chloro-5-nitro- (6CI,8CI);2-AMINO-3-CHLORO-5-NITROPYRIDINE ISO 9001:2015 REACH
CBNumber
CB0425012
Molecular Formula
C5H4ClN3O2
Formula Weight
173.56
MOL File
22353-35-1.mol
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2-AMINO-3-CHLORO-5-NITROPYRIDINE Property

Melting point:
211-213℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
Appearance
Light yellow to yellow Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A595730
Product name
2-Amino-3-chloro-5-nitropyridine
Packaging
500mg
Price
$85
Updated
2021/12/16
TRC
Product number
A595730
Product name
2-Amino-3-chloro-5-nitropyridine
Packaging
1g
Price
$115
Updated
2021/12/16
ChemScene
Product number
CS-W021548
Product name
2-Amino-3-chloro-5-nitropyridine
Packaging
1g
Price
$31
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA55264
Product name
2-Amino-3-chloro-5-nitropyridine
Packaging
500mg
Price
$100
Updated
2021/12/16
ChemScene
Product number
CS-W021548
Product name
2-Amino-3-chloro-5-nitropyridine
Packaging
5g
Price
$129
Updated
2021/12/16
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2-AMINO-3-CHLORO-5-NITROPYRIDINE Chemical Properties,Usage,Production

Synthesis

4214-76-0

22353-35-1

Under argon protection, N-chlorosuccinimide (0.53 g, 3.95 mmol) was slowly added to a solution of 2-amino-5-nitropyridine (0.50 g, 3.59 mmol) in anhydrous toluene (7.18 mL). The reaction mixture was stirred continuously at 80 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and diluted with 15 mL of water. Subsequently, extraction was carried out with ethyl acetate and the organic layer was washed sequentially with saturated sodium bicarbonate solution and brine. The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure, and the resulting crude product was purified by column chromatography (silica gel 60N, gradient elution of n-hexane/ethyl acetate = 80/20 to 60/40) to afford 2-amino-3-chloro-5-nitropyridine (0.40 g, 2.30 mmol, 64% yield) as a yellow solid. The structure of the product was analyzed by nuclear magnetic resonance hydrogen spectrum (1H NMR, 500 MHz, DMSO-d6) δ 8.84 (d, J = 2.5 Hz, 1H), 8.35 (d, J = 2.5 Hz, 1H), 7.91 (brs, 1H); nuclear magnetic resonance carbon spectrum (13C NMR, 125 MHz, DMSO-d6) δ 112.58, 132.14, 135.01, 145.25, 159.75; high-resolution mass spectrometry (HRMS, ESI-TOF, m/z) calculated values of C5H4ClN3O2Na [M + Na]+: 195.9884, 197.9856, measured values: 195.9878, 197.9847 confirmed.

References

[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3853 - 3860
[2] Journal of the Chemical Society, 1951, p. 2590,2593
[3] Zhurnal Obshchei Khimii, 1940, vol. 10, p. 1827,1836
[4] Chem. Zentralbl., 1940, vol. 111, # II, p. 614
[5] Journal of the Chemical Society, 1951, p. 2590,2593

2-AMINO-3-CHLORO-5-NITROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-3-CHLORO-5-NITROPYRIDINE Suppliers

PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
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55
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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62
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
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50
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
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65
China Langchem Inc.
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0086-21-58956006
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0086-21-58956100
Country
China
ProdList
7811
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57
Shanghai Raise Chemical Technology Co.,Ltd
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+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
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55
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2647
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55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
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sales@worldyachem.com
Country
China
ProdList
9476
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Cool Pharm, Ltd
Tel
021-60455363 18019463053
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50966098
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sales@coolpharm.com
Country
China
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12346
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View Lastest Price from 2-AMINO-3-CHLORO-5-NITROPYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-AMINO-3-CHLORO-5-NITROPYRIDINE 22353-35-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-03
Henan Fengda Chemical Co., Ltd
Product
2-AMINO-3-CHLORO-5-NITROPYRIDINE 22353-35-1
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Dideu Industries Group Limited
Product
2-AMINO-3-CHLORO-5-NITROPYRIDINE 22353-35-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-22

22353-35-1, 2-AMINO-3-CHLORO-5-NITROPYRIDINERelated Search:


  • 2-AMINO-3-CHLORO-5-NITROPYRIDINE
  • 3-chloro-5-nitropyridin-2-amine
  • 3-Chloro-5-nitro-2-pyridinamine
  • Pyridine,2-amino-3-chloro-5-nitro- (6CI,8CI)
  • 2-AMINO-3-CHLORO-5-NITROPYRIDINE, 95+%
  • 3-Chloro-5-nitro-pyridin-2-ylamine
  • 2-Pyridinamine, 3-chloro-5-nitro-
  • 2-AMINO-3-CHLORO-5-NITROPYRIDINE ISO 9001:2015 REACH
  • 2-amino 5-nitro 3-chloro pyridine
  • 22353-35-1
  • Boronic Acid
  • Heterocycle-Pyridine series
  • amine| alkyl chloride| nitro-compound
  • Pyridine