ChemicalBook > CAS DataBase List > 2-Amino-5-chloro-3-methylbenzoic acid

2-Amino-5-chloro-3-methylbenzoic acid

Product Name
2-Amino-5-chloro-3-methylbenzoic acid
CAS No.
20776-67-4
Chemical Name
2-Amino-5-chloro-3-methylbenzoic acid
Synonyms
2-aMino-3-Methyl-5-chlorobenzoic acid;2-Amino-5-chloro-m-toluic Acid;Chlorantraniliprole intermediate;2-Amino-5-chloro-3-methylbenzene;5-Chloro-3-methylanthranilic Acid;3-METHYL-5-CHLORO-ANTHRANILIC ACID;2-Amino-5-chloro-3-methylbenzoicaci;-Amino-5-chloro-3-methylbenzoic acid;2-AMINO-5-CHLORO-3-METHYLBENZOIC ACID;2-Amino-5-chloro-3-methylbenzoicAcid>
CBNumber
CB0446000
Molecular Formula
C8H8ClNO2
Formula Weight
185.61
MOL File
20776-67-4.mol
More
Less

2-Amino-5-chloro-3-methylbenzoic acid Property

Melting point:
239-243 °C (lit.)
Boiling point:
348.4±42.0 °C(Predicted)
Density 
1.401±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
very slightly in Methanol
form 
powder to crystal
pka
4?+-.0.10(Predicted)
color 
White to Light yellow to Light red
InChI
InChI=1S/C8H8ClNO2/c1-4-2-5(9)3-6(7(4)10)8(11)12/h2-3H,10H2,1H3,(H,11,12)
InChIKey
KOPXCQUAFDWYOE-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(Cl)=CC(C)=C1N
CAS DataBase Reference
20776-67-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
HS Code 
29224999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
643513
Product name
2-Amino-5-chloro-3-methylbenzoic acid
Purity
97%
Packaging
25g
Price
$120.35
Updated
2025/07/31
Sigma-Aldrich
Product number
643513
Product name
2-Amino-5-chloro-3-methylbenzoic acid
Purity
97%
Packaging
5g
Price
$36.8
Updated
2023/06/20
TCI Chemical
Product number
A2399
Product name
2-Amino-5-chloro-3-methylbenzoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$25
Updated
2025/07/31
TCI Chemical
Product number
A2399
Product name
2-Amino-5-chloro-3-methylbenzoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$97
Updated
2025/07/31
TRC
Product number
A617373
Product name
2-Amino-5-chloro-3-methylbenzoic Acid
Packaging
10g
Price
$75
Updated
2021/12/16
More
Less

2-Amino-5-chloro-3-methylbenzoic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow crystalline powder

Uses

2-Amino-5-chloro-3-methylbenzoic Acid is a useful research chemical for the preparation of benzoyl urea containing anthranillic acid groups with insecticidal activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

4389-45-1

20776-67-4

General procedure for the synthesis of 2-amino-5-chloro-3-methylbenzoic acid from 2-amino-3-methylbenzoic acid: In a 100 mL round-bottomed flask, 20 mL of 2-amino-3-methylbenzoic acid, 50 mL of N,N-dimethylformamide (DMF), and 30 mmol of N-chlorosuccinimide (or N-bromosuccinimide) were added. The mixture was stirred under reflux conditions for 3 hours. After the reaction was completed, the reaction solution was poured into ice water. The pH was adjusted to 6 with dilute hydrochloric acid and then filtered. The resulting solid was washed with a small amount of ethanol to give a gray solid 2-amino-5-halogeno-3-methylbenzoic acid (halogen was chlorine or bromine). The yield was 83%.

References

[1] Journal of Agricultural and Food Chemistry, 2012, vol. 60, # 44, p. 10942 - 10951
[2] Australian Journal of Chemistry, 2014, vol. 67, # 10, p. 1491 - 1503
[3] Patent: CN103450154, 2016, B. Location in patent: Paragraph 0063-0065
[4] Patent: CN104031026, 2017, B. Location in patent: Paragraph 0051; 0052; 0053; 0054
[5] Journal of Chemical Research, 2008, # 9, p. 530 - 533

2-Amino-5-chloro-3-methylbenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Amino-5-chloro-3-methylbenzoic acid Suppliers

ANDA CHEM TECH CO., LTD.
Tel
15314272228
Email
321390262@qq.com
Country
China
ProdList
46
Advantage
58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd
Tel
027-027-59308705 18871579363
Fax
027-59308705
Email
1248680011@qq.com
Country
China
ProdList
9850
Advantage
58
Xi'an Synthetize Industrial Co., Ltd.
Tel
18133923743
Email
pengfei@xa-sks.com
Country
China
ProdList
10
Advantage
58
Shandong Nabaichuan Chemical Sales Co., Ltd.
Tel
178-8833-8888
Email
582133786@qq.com
Country
China
ProdList
17
Advantage
58
Zhangjiagang Free Trade Zone Kailite Chemical Co., Ltd.
Tel
18606289633 15862625988
Fax
0512-58813106
Email
sales@clentchem.com
Country
China
ProdList
157
Advantage
60
Dalian Tianchi Jiulong Pharmaceutical Technology Co., Ltd
Tel
0411-84176838 13942036801
Email
info@tianchiorg.com
Country
China
ProdList
52
Advantage
58
Qingdao Baiyi Chemical Co., Ltd
Tel
13053388919; 13053388919
Email
1454485610@qq.com
Country
China
ProdList
195
Advantage
58
Jinan Junhe Pharmaceutical Co., Ltd
Tel
13475558980 13475558980
Email
644535754@qq.com
Country
China
ProdList
319
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
MedicalChem(Yancheng)Manuf.Co.,Ltd
Tel
+86-515-84383180
Fax
+86-515-84383182
Email
sales@medicalchem.com
Country
China
ProdList
80
Advantage
69
More
Less

View Lastest Price from 2-Amino-5-chloro-3-methylbenzoic acid manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
2-amino-5-chloro-3-methylbenzoic acid 20776-67-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-08-22
Shaanxi Dideu New Materials Co. Ltd
Product
2-Amino-5-chloro-3-methylbenzoic acid 20776-67-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Amino-5-chloro-3-methylbenzoic acid 20776-67-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2025-05-07

20776-67-4, 2-Amino-5-chloro-3-methylbenzoic acidRelated Search:


  • 2-aMino-3-Methyl-5-chlorobenzoic acid
  • 2-aMino-3-Methyl-5-chlorobenzoic acid (2-aMino-5-chloro-3-Methylbenzoate)
  • 2-AMino-5-chloro-3-Methylbenzoic acid, 95+%
  • 3-METHYL-5-CHLORO-ANTHRANILIC ACID
  • 2-AMINO-5-CHLORO-3-METHYLBENZOIC ACID
  • BENZOIC ACID, 2-AMINO-5-CHLORO-3-METHYL-
  • 2-Amino-5-chloro-3-methylbenzoicAcid&gt
  • 2-Amino-5-chloro-3-methylbenzoicaci
  • 2-Amino-5-chloro-m-toluic Acid
  • 5-Chloro-3-methylanthranilic Acid
  • 2-Amino-5-chloro-3-methylbenzoic acid USP/EP/BP
  • -Amino-5-chloro-3-methylbenzoic acid
  • Chlorantraniliprole intermediate
  • 2-Amino-5-chloro-3-methylbenzene
  • 20776-67-4
  • 2776-67-4
  • C8H8NO2Cl
  • H2NC6H2ClCH3CO2H
  • Aromatic Amino Acids
  • Peptide Synthesis
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Aromatic Amino Acids
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • 20776-67-4