ChemicalBook > CAS DataBase List > 2,4,5-Triamino-6-hydroxypyrimidine sulfate
2,4,5-Triamino-6-hydroxypyrimidine sulfate
application- Product Name
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate
- CAS No.
- 35011-47-3
- Chemical Name
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate
- Synonyms
- 2,5,6-Triamino-4(1H)-pyrimidinone sulfate;2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE HYDRATE;TAPOS;4-Hydr;NSC 167378;Folic acid Impurity 69;Folic Acid Impurity 26;Folic Acid Impurity B Sulfate;Folic Acid EP Impurity B Sulfate;4-HYDROXY-2,5,6-TRIAMINOPYRIMIDINE
- CBNumber
- CB0447678
- Molecular Formula
- C4H9N5O5S
- Formula Weight
- 239.21
- MOL File
- 35011-47-3.mol
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2,4,5-Triamino-6-hydroxypyrimidine sulfate Property
- Melting point:
- ≥300 °C(lit.)
- RTECS
- UW7175000
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in DMSO.
- form
- Solid
- color
- Pale Yellow
- InChI
- InChI=1S/C4H7N5O.H2O4S/c5-1-2(6)8-4(7)9-3(1)10;1-5(2,3)4/h5H2,(H5,6,7,8,9,10);(H2,1,2,3,4)
- InChIKey
- RSKNEEODWFLVFF-UHFFFAOYSA-N
- SMILES
- NC1C(N=C(N)NC=1N)=O.S(O)(O)(=O)=O
- CAS DataBase Reference
- 35011-47-3(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHR2001
- Product name
- Folic Acid Impurity B
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 20MG
- Price
- $647
- Updated
- 2024/03/01
TCI Chemical
- Product number
- T0335
- Product name
- 2,4,5-Triamino-6-hydroxypyrimidine Sulfate Hydrate
- Purity
- >90.0%(T)
- Packaging
- 25g
- Price
- $38
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B21989
- Product name
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate, 97%
- Packaging
- 25g
- Price
- $49.65
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B21989
- Product name
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate, 97%
- Packaging
- 100g
- Price
- $152.65
- Updated
- 2024/03/01
TRC
- Product number
- H971250
- Product name
- 6-Hydroxy-2,4,5-triaminopyrimidine,Sulfate
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
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2,4,5-Triamino-6-hydroxypyrimidine sulfate Chemical Properties,Usage,Production
application
6-Hydroxy-2,4,5-triaminopyrimidine, Sulfate (cas# 35011-47-3) is a compound useful in organic synthesis.
Chemical Properties
yellow-beige crystalline powder
Uses
2,4,5-Triamino-6-hydroxypyrimidine Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity.
Uses
2,4,5-Triamino-6-hydroxypyrimidine sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities.
Purification Methods
This salt has very low solubility in H2O. It is best purified by conversion into the dihydrochloride salt, which is then re-converted to the insoluble sulfate salt. The sulfate salt (2.57g, 10mmoles) is suspended in H2O (20mL) containing BaCl2 (10mmoles) and stirred in a boiling water bath for 15minutes. After cooling, the insoluble BaSO4 is filtered off and washed with boiling H2O (10mL). The combined filtrate and washings are made acidic with HCl and evaporated to dryness. The residual hydrochloride salt is recrystallised from H2O by adding conc HCl whereby the dihydrochloride salt separates as clusters which darken at 260o and dec > 300o[darkening > 360o]. [Baugh & Shaw J Org Chem 29 3610 1964, King & Spengley J Chem Soc 2144 1952]. The hydrochloride is then dissolved in H2O, and while hot an equivalent of H2SO4 is added when the sulfate separates as a white microcrystalline solid which is filtered off washed liberally with H2O and dried in vacuum over P2O5. [Albert & Wood J Appl Chem London 3 521 1953, UV: Cavalieri et al. J Am Chem Soc 70 3875 1948; see also Pfleiderer Chem Ber 90 2272 1957, Traube Chem Ber 33 1371 1900.] The hydrochloride has m > 300o. [Beilstein 25 II 384, 25 III/IV 3648.]
2,4,5-Triamino-6-hydroxypyrimidine sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4,5-Triamino-6-hydroxypyrimidine sulfate manufacturers
PNP Biotech Co. Ltd
- Product
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- HPLC>99%
- Supply Ability
- Inquiry
- Release date
- 2022-09-16
Shaanxi Dideu Medichem Co. Ltd
- Product
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50ton
- Release date
- 2020-05-19
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- 2,4,5-Triamino-6-hydroxypyrimidine sulfate 35011-47-3
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2021-11-26
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