ARACHIDONIC ACID SODIUM SALT
- Product Name
- ARACHIDONIC ACID SODIUM SALT
- CAS No.
- 6610-25-9
- Chemical Name
- ARACHIDONIC ACID SODIUM SALT
- Synonyms
- SODIUM ARACHIDONATE;Arachidonicacidsodiumsal;ARACHIDONIC ACID SODIUM SALT;5Z,8Z,11Z,14Z-EICOSATETRAENOIC;5,8,11,14-EICOSATETRAENOIC ACID;Arachidonic acid sodium salt from;EICOSA-5Z,8Z,11Z,14Z-TETRAENOIC ACID;Arachidonic Acid, Fungal sp., Sodium Salt;ARACHIDONIC ACID SODIUM FROM PORCINELIVE R;5,8,11,14-EICOSATETRAENOIC ACID SODIUM SALT
- CBNumber
- CB0461041
- Molecular Formula
- C20H31NaO2
- Formula Weight
- 326.45
- MOL File
- 6610-25-9.mol
ARACHIDONIC ACID SODIUM SALT Property
- Flash point:
- 113℃
- storage temp.
- -20°C
- solubility
- methanol: 50 mg/mL, clear, colorless to faintly yellow
- form
- waxy solid
- color
- white to off-white
- biological source
- Mortierella alpina
- Water Solubility
- water: 5mg/mL
- InChIKey
- DDMGAAYEUNWXSI-XVSDJDOKSA-M
- SMILES
- C(/C/C=C\CCCC([O-])=O)=C/C/C=C\C/C=C\CCCCC.[Na+]
Safety
- Risk Statements
- 19
- WGK Germany
- 3
- RTECS
- JX3874000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML1395
- Product name
- Arachidonic acid sodium salt from
- Purity
- ≥98.5% (GC)
- Packaging
- 5mg
- Price
- $47.8
- Updated
- 2025/07/31
- Product number
- SML1395
- Product name
- Arachidonic acid sodium salt from
- Purity
- ≥98.5% (GC)
- Packaging
- 25mg
- Price
- $185
- Updated
- 2025/07/31
- Product number
- 5.32830
- Product name
- Arachidonic Acid, Fungal sp., Sodium Salt - CAS 6610-25-9 - Calbiochem
- Purity
- Precursor for prostaglandins, prostacyclin, and thromboxane.
- Packaging
- 100MG
- Price
- $242
- Updated
- 2022/05/15
- Product number
- 10006607
- Product name
- Arachidonic Acid (sodium salt)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $50
- Updated
- 2024/03/01
- Product number
- 10006607
- Product name
- Arachidonic Acid (sodium salt)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $94
- Updated
- 2024/03/01
ARACHIDONIC ACID SODIUM SALT Chemical Properties,Usage,Production
Uses
Arachidonic acid is used in assays to measure activity of oxidizing enzymes, such as cyclooxygenase, as well as in assays to determine platelet inhibition in whole blood. Arachidonic acid has been demonstrated to bind to the a subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs), to have a role in the development and progression of prostate cancer, and to enhance formation of lipid bodies in human mast cells.
General Description
Arachidonic acid (AA) is a polyunsaturated ? fatty acid constituent of the phospholipids of cell membranes. Structurally, it is a 20-carbon chain that contains four cis double bonds, which allow the free acid form of AA to be an insoluble oil; this can be converted to the water-soluble sodium salt form within the normal physiological pH range. Arachidonic acid is metabolized by multiple enzymes to yield various metabolites; AA and its metabolites play important roles in a variety of biological processes, including signal transduction, smooth muscle contraction, chemotaxis, cell proliferation and differentiation and apoptosis.
Biochem/physiol Actions
Released arachidonic acid (AA) reacts with molecular oxygen nonenzymatically, through oxidative stress, and enzymatically through the action of oxygenase enzymes. AA is oxidized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via cytochrome p450-catalyzed metabolism. Cellular uptake of arachidonic acid is energy dependent and involves protein-facilitated transport across the plasma membrane.
in vivo
Arachidonic acid sodium salt can be used to induce paw edema models[2].
Administration: 0.5% ? s.c. ? single dose
| Animal Model: | Male Lew rats (4-week-old) induced arthritis[1] |
| Dosage: | 0.07%, 0.15% or 0.32% in diet (w/w) |
| Administration: | 4 weeks |
| Result: | The Arachidonic acid content of phospholipids in the paw was significantly elevated in a dose-dependent manner. |
IC 50
Human Endogenous Metabolite
ARACHIDONIC ACID SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
ARACHIDONIC ACID SODIUM SALT Suppliers
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