Palbociclib-025

Product Name: Palbociclib-025
CAS No.: 2174002-16-3
Chemical Name: Palbociclib-025
Synonyms: N-Formyl Palbociclib;Palbociclib E;Palbociclib Impurity 025;1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-;4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity）;Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
CBNumber: CB04883289
Molecular Formula: C25H29N7O3
Formula Weight: 475.54
MOL File: 2174002-16-3.mol

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Palbociclib-025 Property

Boiling point:: 765.3±70.0 °C(Predicted)
Density: 1.389±0.06 g/cm3(Predicted)
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
pka: 5.24±0.10(Predicted)
color: Light Yellow to Very Dark Yellow

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Hazard and Precautionary Statements (GHS)

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Palbociclib-025 Chemical Properties,Usage,Production

Uses

Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-b-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

Palbociclib-025 Preparation Products And Raw materials

Raw materials

Preparation Products

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Palbociclib-025 Suppliers

China 40 India 1 United States 2 Global 43

Daicel Chiral Technologies (China)CO.,LTD

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Beijing Comparison Pharmaceutical Technology Co., Ltd

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Shanghai Kewel Chemical Co., Ltd.

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Nanjing XiZe Biotechnology CO., Ltd.

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ATK CHEMICAL COMPANY LIMITED

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Artis Biotech Co. Ltd.

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Shanghai Chaolan Chemical Technology Center

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Chengdu Novel Biomedical Co., Ltd.

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SHANGHAI FDC-CHEMICAL CO.,LTD

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2174002-16-3, Palbociclib-025Related Search:

4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Palbociclib Impurity N-Oxide 4-[6-[(8-cyclopentyl-6-ethenyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid tert-butyl ester 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Palbociclib Impurity 87 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxy-1-piperazinyl)-2-pyridinyl]amino]-5-methyl- 6-bromo-8-cyclopentyl-5-methyl-Pyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione Palbociclib Impurity 91 Palbociclib Impurity I 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Palbociclib Impurity 37 rac-trans-4-Desfluoro-4-methoxy Paroxetine Hydrochloride Paroxetine Impurity 4 Paroxetine HCl Hemihydrate EP Impurity C HCl

Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde

N-Formyl Palbociclib

1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-

Palbociclib E

Palbociclib Impurity 025

4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity）

2174002-16-3