BENFLUOREX HYDROCHLORIDE
- Product Name
- BENFLUOREX HYDROCHLORIDE
- CAS No.
- 23602-78-0
- Chemical Name
- BENFLUOREX HYDROCHLORIDE
- Synonyms
- s780;s992;S-780;jp992;se780;SE-780;D07192;Minolip;Mediaxal;BENFLUREX
- CBNumber
- CB0497956
- Molecular Formula
- C19H20F3NO2
- Formula Weight
- 351.36
- MOL File
- 23602-78-0.mol
BENFLUOREX HYDROCHLORIDE Property
- Boiling point:
- 420.5±45.0 °C(Predicted)
- Density
- 1.183±0.06 g/cm3(Predicted)
- pka
- 8.23±0.10(Predicted)
Safety
- WGK Germany
- 2
- RTECS
- KL8275000
- Toxicity
- LD50 oral in mouse: 2300mg/kg
N-Bromosuccinimide Price
- Product number
- FB104002
- Product name
- Benfluorex
- Packaging
- 500mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB104002
- Product name
- Benfluorex
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB104002
- Product name
- Benfluorex
- Packaging
- 2g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 0270CA
- Product name
- Benfluorex
- Packaging
- 1g
- Price
- $137
- Updated
- 2021/12/16
- Product number
- FB104002
- Product name
- Benfluorex
- Packaging
- 5G
- Price
- $200
- Updated
- 2021/12/16
BENFLUOREX HYDROCHLORIDE Chemical Properties,Usage,Production
Originator
Mediator,Servier,France,1976
Uses
antihyperlipoproteinemic
Definition
ChEBI: Benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester is a benzoate ester.
Manufacturing Process
To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β-
hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were
added successively 15 parts of 4.7N hydrochloric ether and a solution of 14
parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition
required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from
230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)-
2-(β-benzoyloxyethyl)amino propane hydrochloride
melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts
ether are added, then 10 parts of a concentrated solution of ammonium
hydroxide. The mixture is stirred a few minutes until the salt is dissolved,
then the ethered solution is poured off and dried. After the ether is
eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β-
benzoyloxyethyl)amino propane are obtained; the base is a colorless oil.
Therapeutic Function
Antihyperlipidemic, Cardiovascular
BENFLUOREX HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
BENFLUOREX HYDROCHLORIDE Suppliers
View Lastest Price from BENFLUOREX HYDROCHLORIDE manufacturers
- Product
- BENFLUOREX HYDROCHLORIDE 23602-78-0
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 100g , 1kg, 5kg , 50kg
- Release date
- 2020-01-07