ChemicalBook > CAS DataBase List > Tanomastat

Tanomastat

Product Name
Tanomastat
CAS No.
179545-77-8
Chemical Name
Tanomastat
Synonyms
D03802;TANOMASTAT;Tanomastat (usan/inn);(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid;(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid;1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid;[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
CBNumber
CB0506810
Molecular Formula
C23H19ClO3S
Formula Weight
410.91
MOL File
179545-77-8.mol
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Tanomastat Property

Melting point:
110-110.5°C
Boiling point:
620.1±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
4.01±0.23(Predicted)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
179545-77-8
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19258
Product name
Tanomastat
Purity
≥98%
Packaging
500μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19258
Product name
Tanomastat
Purity
≥98%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
19258
Product name
Tanomastat
Purity
≥98%
Packaging
5mg
Price
$213
Updated
2024/03/01
Cayman Chemical
Product number
19258
Product name
Tanomastat
Purity
≥98%
Packaging
10mg
Price
$388
Updated
2024/03/01
TRC
Product number
T006900
Product name
Tanomastat
Packaging
5mg
Price
$180
Updated
2021/12/16
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Tanomastat Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)

Uses

Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).

Definition

ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.

Tanomastat Preparation Products And Raw materials

Raw materials

Preparation Products

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Tanomastat Suppliers

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179545-77-8, TanomastatRelated Search:

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  • TANOMASTAT
  • BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid
  • (S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid
  • (S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid
  • D03802
  • Tanomastat (usan/inn)
  • (S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
  • [1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
  • 1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
  • 179545-77-8
  • C23H19ClO3S
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds