Tanomastat

Product Name: Tanomastat
CAS No.: 179545-77-8
Chemical Name: Tanomastat
Synonyms: D03802;TANOMASTAT;Tanomastat (usan/inn);(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid;(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid;1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid;[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
CBNumber: CB0506810
Molecular Formula: C23H19ClO3S
Formula Weight: 410.91
MOL File: 179545-77-8.mol

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Tanomastat Property

Melting point:: 110-110.5°C
Boiling point:: 620.1±55.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
pka: 4.01±0.23(Predicted)
form: Solid
color: White to Off-White
CAS DataBase Reference: 179545-77-8

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19258
Product name: Tanomastat
Purity: ≥98%
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 19258
Product name: Tanomastat
Purity: ≥98%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 19258
Product name: Tanomastat
Purity: ≥98%
Packaging: 5mg
Price: $213
Updated: 2024/03/01

Cayman Chemical

Product number: 19258
Product name: Tanomastat
Purity: ≥98%
Packaging: 10mg
Price: $388
Updated: 2024/03/01

TRC

Product number: T006900
Product name: Tanomastat
Packaging: 5mg
Price: $180
Updated: 2021/12/16

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Tanomastat Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)

Uses

Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.

Uses

A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).

Definition

ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.

Tanomastat Preparation Products And Raw materials

Raw materials

Preparation Products

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Tanomastat Suppliers

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179545-77-8, TanomastatRelated Search:

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TANOMASTAT

BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid

(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid

(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid

D03802

Tanomastat (usan/inn)

(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid

[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-

1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-

179545-77-8

C23H19ClO3S

Chiral Reagents

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds