Tanomastat
- Product Name
- Tanomastat
- CAS No.
- 179545-77-8
- Chemical Name
- Tanomastat
- Synonyms
- D03802;TANOMASTAT;Tanomastat (usan/inn);(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid;(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid;1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid;[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
- CBNumber
- CB0506810
- Molecular Formula
- C23H19ClO3S
- Formula Weight
- 410.91
- MOL File
- 179545-77-8.mol
Tanomastat Property
- Melting point:
- 110-110.5°C
- Boiling point:
- 620.1±55.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 4.01±0.23(Predicted)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 179545-77-8
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19258
- Product name
- Tanomastat
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 19258
- Product name
- Tanomastat
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 19258
- Product name
- Tanomastat
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $213
- Updated
- 2024/03/01
- Product number
- 19258
- Product name
- Tanomastat
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $388
- Updated
- 2024/03/01
- Product number
- T006900
- Product name
- Tanomastat
- Packaging
- 5mg
- Price
- $180
- Updated
- 2021/12/16
Tanomastat Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)
Uses
Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).
Definition
ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.