Azido-PEG7-COOtBu
- Product Name
- Azido-PEG7-COOtBu
- CAS No.
- 2596867-40-0
- Chemical Name
- Azido-PEG7-COOtBu
- Synonyms
- N3-PEG7-COOtBu;Azido-PEG7-COOtBu;Azido-PEG7-tBu Ester;N3-PEG7-CH2CH2COOtBu;tert-butyl 1-azido-3,6,9,12,15,18,21-heptaoxatetracosan-24-oate;4,7,10,13,16,19,22-Heptaoxatetracosanoic acid, 24-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB05478194
- Formula Weight
- 479.57
- MOL File
- 2596867-40-0.mol
Azido-PEG7-COOtBu Chemical Properties,Usage,Production
Uses
Azido-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological Activity
Azido-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Azido-PEG7-COOtBu Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG7-COOtBu Suppliers
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 400-9189898 17359873007
- sales@sinopeg.com
- Country
- China
- ProdList
- 530
- Advantage
- 58
- Tel
- 0371-0371-55153829 18003835034
- 2853979819@qq.com
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 15841022315
- sales@affinitytech.cn
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- SY06@accelachem.com
- Country
- China
- ProdList
- 7551
- Advantage
- 58
- Tel
- 13356310019 13356310019;
- boyu2024@163.com
- Country
- China
- ProdList
- 3247
- Advantage
- 58
- Tel
- 17721070236 15002190549;
- yanfen2023@126.com
- Country
- China
- ProdList
- 1837
- Advantage
- 58
- Tel
- 15666167041
- 15666167041@163.com
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 176345344 7 17634854698
- 1959525201@qq.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 025-58859352 18651614124
- 2881516338@qq.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- +86-0592-7761068 +8617350879715
- changaiwei@sinopeg.com
- Country
- China
- ProdList
- 411
- Advantage
- 58
- Tel
- +86-15680926068
- 1924344760@confluore.cn
- Country
- China
- ProdList
- 2997
- Advantage
- 58
- Tel
- +undefined18143011203
- info@chemextension.com
- Country
- China
- ProdList
- 42056
- Advantage
- 58
View Lastest Price from Azido-PEG7-COOtBu manufacturers
- Product
- tert-butyl 1-azido-3,6,9,12,15,18,21-heptaoxatetracosan-24-oate 2596867-40-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- azido-PEG7-t-Butyl ester 2596867-40-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23